scholarly journals Expression of epithelial membrane antigen and cytokeratin among Indian workers exposed to cotton fibre dust in textile industries

Author(s):  
Ashish K. Mehta

Background: In India, around 20 million workers are engaged in the textile industries. However, the prevalence of byssinosis has been little reported. Aims: To determine the prevalence of byssinosis and other respiratory disorders among workers exposed to cotton dust in textile mills in Delhi, India. Methods: Sputum samples were collected from 156 workers employed in 15 cotton textile mills, and expression of epithelial membrane antigen (EMA) and cytokeratin (CK) marker proteins was investigated. Information regarding respiratory symptoms, certain personal characteristics and occupational history was also gathered. Results: Symptoms were observed in 56.41% of the workers. Expression of EMA and CK was observed in 27.5% and 50% of the workers, respectively. Expression of EMA and CK was significantly associated with smoking and duration of employment. Conclusion: Measures are needed to reduce dust levels in the workplace, and to discourage smoking and alcohol consumption among the textile workers.

2003 ◽  
Vol 41 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Yih-Ming SU ◽  
Jenn-Rong SU ◽  
Jia-Yih SHEU ◽  
Ching-Hui LOH ◽  
Saou-Hsing LIOU

1993 ◽  
Vol 23 (2) ◽  
pp. 333-342 ◽  
Author(s):  
David C. Christiani ◽  
David H. Wegman ◽  
Ellen A. Eisen ◽  
Ting-Ting Ye ◽  
Pei-Lian Lu ◽  
...  

2019 ◽  
Author(s):  
Asaad Ahmed Nafees ◽  
Sara De Matteis ◽  
Muhammad Masood Kadir ◽  
Peter Burney ◽  
David Coggon ◽  
...  

Abstract Background In the Pakistani textile industry the prevalence of workplace respiratory illnesses, including byssinosis, is high. This study aims to determine the effectiveness of a multifaceted intervention package in reducing dust levels in cotton mills, decreasing the frequency of respiratory symptoms among cotton textile workers, and improving their lung function. Methods/design We will conduct a cluster-randomized controlled trial at 28 textile mills in Karachi. The intervention will comprise: training in occupational health for all workers and managers backed by regular refresher sessions; the formation of workplace committees to draw up, agree and promote a health and safety plan that includes wet mopping, safe disposal of cotton dust, and the use of simple face masks, as well as further publicity about the risks from cotton dust; and provision of adequate supplies of face masks to support the health and safety plan. Participating mills will be randomized to intervention and control arms following a baseline survey. The impact of the intervention will be determined through follow-up surveys conducted at 3, 12 and 18 months. Data collection in the surveys will include spirometry, questionnaire-based interviews and cotton dust measurements. Discussion If successful, the study may pave the way for simple, low-cost interventions that can help reduce cotton dust levels in textile mills, and improve the respiratory health of textile workers in developing countries such as Pakistan.


CHEST Journal ◽  
1989 ◽  
Vol 95 (5) ◽  
pp. 997-1003 ◽  
Author(s):  
E. Neil Schachter ◽  
Mary C. Kapp ◽  
Gerald J. Beck ◽  
Lucinda R. Maunder ◽  
Theodore J. Witek

2011 ◽  
Vol 29 (2) ◽  
pp. 114-120 ◽  
Author(s):  
Safia Beshir ◽  
Heba Mahdy-Abdallah ◽  
Amal Saad-Hussein

Exposure to cotton dust in industrial environments causes inflammation in the airways of the exposed workers. This may manifest as respiratory complaints and changes in the respiratory functions after work shift and in the baseline of their ventilatory functions. The study aimed to investigate the effect of occupational exposure to cotton dust on respiratory symptoms, ventilatory functions and pro-inflammatory cytokine levels (tumor necrosis factor α, interleukin 6 and interleukin 1β). The study was conducted on 63 textile workers and 65 nonexposed subjects. Both groups were matched for age, socioeconomic status and smoking habit. The respirable dust measured in the workplace did not exceed the permissible values of the Egyptian law 1994. The bacterial counts detected were within the occupational exposure limits of the industrial settings. The results revealed that the percentage of respiratory symptoms was higher in textile workers. Respiratory complaints were chronic cough (33.2%), chronic bronchitis (39.7%) and dyspnea (23.8%) in textile workers compared to (6.2%, 6.2% and 1.5%), respectively, in controls. There was a marked reduction in the ventilatory functions (forced vital capacity and forced expiratory volume in 1 s) in the textile workers compared to the controls. The additive effect of smoking on the ventilatory functions was not apparent. The ventilatory functions of the workers were significantly positively correlated with the duration of exposure. The cytokines were insignificantly higher in the textile workers compared to their controls. The textile workers with respiratory complaints showed significant decline in ventilatory functions and elevation in the cytokine levels compared to the nonsymtomatizing workers with significant difference in interleukin 1β and interleukin 6. In conclusion, the results supported the fact that exposure to cotton dust deteriorates ventilatory functions and elevates proinflammatory cytokine levels. Analysis of the release of cytokines can be used to evaluate the immune responses to organic dust-induced airway inflammation.


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