PREVENTION OF PURULENT-SEPTIC COMPLICATIONS DURING LAPAROSCOPIC SURGERIES ON PELVIC ORGANS WITH THE RISK OF VAGINAL MICROBIOTA CONTAMINATION

2020 ◽  
Vol 16 (71) ◽  
pp. 049
Author(s):  
V. M. Zaporozhan ◽  
I. Z. Gladchuk ◽  
N. M. Rozhkovska ◽  
A. G. Volyanska ◽  
O. I. Shevchenko ◽  
...  
Keyword(s):  
Vaginal Microbiota ◽  
Septic Complications ◽  
Pelvic Organs

Clinical efficiency of correction of the state of vaginal microbiota in women with disorders of reproductive health and the postpartum purulent-septic complications in anamnesis

2018 ◽  
pp. 40-43
Author(s):  
V. Pyrohova ◽  
◽  
Yu. Feita ◽  
S. Shurpyak ◽  
◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Topical Therapy ◽  
Routine Clinical Practice ◽  
Vaginal Microbiota ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Aerobic Vaginitis ◽  
Septic Complications ◽  
Lactic Bacteria ◽  
Observation Results

Vaginal flora plays an important role in the functioning of the reproductive system. The objective: was to evaluate the efficacy and tolerability of vaginal suppositories of Florica (producer «Lekhim-Kharkiv») in maintaining a normal balance of vaginal microbiota to prevent recurrences of bacterial vaginosis, aerobic and mixed vaginal dysbiosis. Materials and methods. 45 women of reproductive age (from 22 to 35 years) with burdened reproductive (miscarriage, premature birth) and obstetric (postpartum purulent-septic diseases) history were under observation. Results. Application to maintain a normal balance of the vaginal microbiota and prevent the development of dysbiotic processes after the completion of the main course of treatment of BV and aerobic vaginitis of vaginal suppositories Florica, which contain a specially treated mass of live lactic bacteria in optimal quantities to maintain a healthy balance of the microflora of the female sexual sphere (5107 Lactobacillus acidophilus and Bifidobacterium) allows to reduce the frequency of recurrence of BV in 2.9 times. Conclusion. The frequency of recurrence of BV in routine clinical practice is 35.0% during 6 months of observation, which indicates the need to develop effective measures to prevent the recurrence of vaginal dysbiotic processes. Key words: vaginal microbiota, vaginal dysbiosis, bacterial vaginosis, aerobic vaginitis, topical therapy.

Analysis of the microbial spectrum in women with purulent-inflammatory diseases of the pelvic organs in the context of the provision of urgent surgical gynecological care, taking into account risk factors

2020 ◽  
pp. 38-41
Author(s):  
E. Grigoriev ◽  
◽  
P. Sytnik ◽  
A. Dyakov ◽  
O. Sytnik ◽  
...  
Keyword(s):  
Risk Factors ◽  
Inflammatory Diseases ◽  
Bacterial Flora ◽  
Termination Of Pregnancy ◽  
Purulent Discharge ◽  
Septic Complications ◽  
Pelvic Organs ◽  
History Of ◽  
Microbial Associations ◽  
Microbial Spectrum

The objective: determination and analysis of the microbial spectrum in women with purulent-inflammatory diseases of the pelvic organs in the conditions of providing urgent surgical gynecological care, taking into account risk factors. Materials and methods. The study was conducted on the basis of City Clinical Hospital № 1 in Odessa during 2015–2019. 47 patients who underwent urgent surgical treatment for purulent-inflammatory diseases of the pelvic organs were examined. The average age of the patients was 38.3±1.5 g. Patients were in the hospital on average 10.5±0.5 days. The analysis was carried out using classical methods with the results of an antibioticogram. Results. Purulent-septic complications were observed in 18 women (38.3%). When conducting intraoperative screening of microflora isolated from abscesses, blood, purulent discharge, drainage and postoperative wounds, 30 (63.8%) patients were obtained and studied. A detailed picture was as follows: Staphylococcus epidermidis – 46.2%, E. сoli – 20.5%, Staphylococcus saprophyticus – 12.8%, Staphylococcus heholiticus – 5.1%, Micrococus – 5.1%, Enterococcus faecalis – 2.6%, Bacillus saprophyticus – 2.6%, Corynebacterium – 2.6%, Streptococcus saprophyticus – 2.6%. By combining staphylococci in one group, it was found that the proportion of Staphylococcus from the entire microflora obtained was 66%. It was found that out of 30 cases of introoperative seeding of bacterial flora, 22 women (73.32%) had a history of artificial termination of pregnancy (OR=1.93). So, in 6 patients (20.0% of the total number of microflora cases) microbial associations of various composition took place, and in 100% of cases the associations included staphylococci. Further analysis revealed a dependence on the presence of microbial association and the presence in the woman’s history of artificial abortions. So with 6 cases of intraoperative registration of microbial associations, 5 women had a history of artificial termination of pregnancy, that is, 83.0% (RR=1.67). Conclusions. 1. According to the bacteriological laboratory of City Clinical Hospital No. 1, the species composition of microflora isolated from abscesses, blood, and purulent discharge was obtained and studied in 30 patients. Thus, the bacterial culture of the total number of patients allocated in 63.8%. 2. Among pathogens of purulent-inflammatory diseases of the pelvic organs and purulent-septic complications, staphylococcus (66%), less often Escherichia coli (20.6%). 3. During the study, it was found that out of 30 patients with a bacterial culture, pathogens in the form of monocultures were isolated in 24 patients (80%), and the presence of bacterial associations was confirmed in 6 (20%) patients. Staphylococci were present in 100% of all cases of microbial associations, and E. coli in 50.0%. 4. The analysis revealed a dependence on the presence in a woman’s history of artificial abortions and registration of the microbial spectrum. So out of 30 cases of intraoperative inoculation of the bacterial flora, 22 women (73.32%) had a history of artificial termination of pregnancy (OR=1.93). And out of 6 cases of registration of microbial associations, 5 women had a history of abortion, that is, 83.0% (RR=1.67). Key words: purulent-inflammatory diseases of the pelvic organs, microbial spectrum, risk factors.

EVALUATION OF HYSTEROSALPINGOGRAPHY VERSUS LAPAROSCOPY IN THE DETERMINATION OF TUBAL FACTORS IN FEMALE INFERTILITY: A HOSPITAL BASED COMPARATIVE STUDY.

2020 ◽  
Vol 4 (9) ◽  
Author(s):  
Richa Choudhary ◽  
Rishikant Sinha
Keyword(s):  
Female Infertility ◽  
Diagnostic Methods ◽  
Panoramic View ◽  
Tubal Patency ◽  
Pelvic Organs ◽  
Clinical Investigations ◽  
Detailed Assessment ◽  
Reproductive Anatomy ◽  
Tubal Pathology

Objectives: Hysterosalpingography and laparoscopy both are the diagnostic methods for assessment of female infertility.  The present study was to compare the evaluation of hysterosalpingography (HSG) versus laparoscopy in determination of tubal factors in female infertility. Methods: Detailed assessment, physical examination and clinical investigations were performed in all 100 infertile female with age 20 years to 40 years. All patients were advised to perform digital HSG. Patients with an abnormal HSG underwent laparoscopy without delay, whereas in patients with a normal HSG, laparoscopy was performed three months after HSG. HSG is best scheduled during the 2nd -5th day interval immediately following the end of menstruation, to minimize risk for infection, avoid interference from intrauterine blood and clot, and to prevent any possibility that the procedure might be performed after conception. Results: Data was analysed by using IBM SPSS version 23 software.  All data was tabulated and percentages were calculated. Mean ± standard deviation was observed. Conclusions: Diagnostic laparoscopy is the gold standard in diagnosing tubal pathology and other intra-abdominal causes of infertility. Other hand, Hysterosalpingography is a frequently utilized diagnostic tool in the assessment of tubal status and detection of uterine anatomical defects in infertility. Hysterosalpingography and laparoscopy are not alternatives but complimentary investigations. But, inadequacy of hysterosalpingography (HSG) in determining the state of tubal patency, emphasizes the need for laparoscopy. Laparoscopy provides both a panoramic view of the pelvic reproductive anatomy and a magnified view of pelvic organs and peritoneal surfaces. Keywords: Female infertility, Tubal patency, HSG, Laparoscopy

Effect of age on outcome in patients with cerebral stroke

2020 ◽  
pp. 41-45
Author(s):  
G. R. Kuchava ◽  
E. V. Eliseev ◽  
B. V. Silaev ◽  
D. A. Doroshenko ◽  
Yu. N. Fedulaev
Keyword(s):  
Ischemic Stroke ◽  
Neurological Deficit ◽  
Neurological Status ◽  
Statistical Correlation ◽  
Multiple Organ ◽  
The Body ◽  
Social Adaptation ◽  
Cerebral Stroke ◽  
Septic Complications ◽  
Risk Of Death

The aim of the study was to assess the course and outcome of cerebral infarction, depending on the age factor and duration of stay in the neuroblock. Materials and methods: a dynamic observation of 494 patients, men and women, aged 38–84 years with acute ischemic stroke of hemispheric localization, which were divided into the three groups depending on age, was performed. Group 1 – younger than 60 years old, group 2–60–70 years old, group 3 – older than 60 years. All patients underwent standard therapy, according to the recommendations for the treatment of ischemic stroke. The patients underwent comprehensive clinical and instrumental monitoring, which included assessment of somatic and neurological status according to the NIH‑NINDS scales at 1st, 3rd, 10th days and at discharge or death; assessment of the level of social adaptation according to the Bartel scale on 1st, 3rd, 10th days and at discharge, clinical and biochemical blood tests, computed tomography of the brain. Assessment of the quality of therapy was carried out according to specially developed maps using methods of statistical correlation analysis. Results: the most pronounced positive dynamics of neurological status was in the 1st group of patients. The regression of neurological deficit in the 2nd group was worse. The minimal dynamics of neurological deficit was in the 3rd group of patients with cerebral stroke. Most often, the death of patients with cerebral stroke occurred from the development of multiple organ disorders. Conclusions: patients over 70 years of age have the greatest risk of death, due to: a decrease in the reactivity of the body, the presence of initially severe concomitant somatic pathology in patients with admission to hospital; accession of secondary somatic and purulent‑septic complications.

Features hormonal hemostasis in patients with benign hyper-plastic processes of breasts

2016 ◽  
pp. 72-74 ◽  
Author(s):  
M. Makarenko ◽  
◽  
D. Govsieiev ◽  
O. Gromova ◽  
L. Martynova ◽  
...  
Keyword(s):  
Luteal Phase ◽  
Reproductive Organs ◽  
Breast Diseases ◽  
Hormonal Changes ◽  
Morphological Investigation ◽  
Fibrocystic Disease ◽  
X Ray ◽  
Pelvic Organs ◽  
Hormone Research ◽  
Gynecological Diseases

The objective: to study the incidence of gynecological diseases, clinical and hormonal parameters of the menstrual cycle in patients with benign hyper-plastic processes of breasts. Patients and methods. 65 women with various forms of mastitis were investigated. The following investigations were conducted: mammologistic and gynecological investigation, mommologistic X-ray investigation, ultrasound of breasts and of the pelvic organs, endometrial aspiration biopsy that was followed by cytology; when it was necessary the diagnostic laparoscopy, colposcopy, hysteroscope with curettage and morphological investigation of the endometrium, hormone research and rectal temperature measurements were conducted. Results. The frequency of the benign breast diseases was set: fibrocystic disease of breast – 32 women (49.2±6.20%), fibrous of breast – 16 women (24.6±5.34%), nodular of breasts – 8 women (12.3±4.07%), fibroadenoma – 6 women (9.2±3.59%), nodular disease of breasts on the background of fibroid changes – 3 women (4.6±2.60%). All in all, 96.9±2.14% of the patients had any gynecological diseases. Thus, the average age of the ‘debut’ of mastitis was 31.4±1.09 years; the hyper-plastic processes in the uterus was 35.2±1.17 years. Anovulation was detected in 17 (47.2±8.3%) patients, the lack of the luteal phase (NLF) was detected in 11 (30.6±7.6) patients. Conclusions. Identified hormonal changes are typical for patients with the hyper-plastic processes of the reproductive organs with different localization (breasts, uterus, ovaries). Due to the commonality of the hormone changes in most cases mastitis is combined with the various gynecological diseases (96.9±2.14%). Key words: gynecological pathology, hormonal changes, breast, factors of risk.

Clinical and microbiological aspects of vaginal microbiota at pregnant with threat of late miscarriages during treatment with vaginal gestagens forms

2017 ◽  
pp. 68-73
Author(s):  
I.P. Polishchuk ◽  
Keyword(s):  
Pregnant Women ◽  
Therapeutic Effect ◽  
Local Treatment ◽  
Vaginal Microbiota ◽  
Control Group ◽  
Before And After ◽  
Low Efficiency ◽  
Late Miscarriage ◽  
Microbiological Aspects ◽  
Micronized Progesterone

The objective: was to examine the effectiveness of treatment of late miscarriage threat by micronized form of progesterone for 100 mg – 3 times a day in the form of gelatin pills and vaginal tablets with lactose. Patients and methods. Under our supervision there were 70 pregnant women with normocenosis of vagina (NCV) without extragenital pathology, which were not performed systemic or local treatment with antibacterial drugs in the last 4 weeks. Among them 25 pregnant women with TLSM treated by gelatin tablets of micronized progesterone (GTP) (group 1); 25 pregnant women with TLSM, treated by vaginal micronized progesterone tablets (VPT) (2nd group) and 20 healthy women with physiological pregnancy – PV (control group). The distribution of women in the group adhered to the principles of randomization. The age of examined women ranged from 19 to 32 years, most pregnant women were aged under 30 years (89.02%). General clinical examination was carried out according to the standard scheme according to the Order MH of Ukraine № 620. Results. During the research we have determined the colpocytologcal dynamics and state of vaginal microbiota in pregnant women with threatened late miscarriage with initial vaginal normocenosis before and after treatment whit vaginal forms of progesterone. Conclusion. The received results showed low efficiency of micronized progesterone gelatin dragee at threat of the late miscarriage that at small therapeutic effect has led to the development of vaginal dysbiosis in all surveyed. In contrast, the use of micronized progesterone vaginal tablets – the maximally rapid therapeutic effect without disturbance of vaginal normocenosis. Key words: the threat of a late miscarriage, vaginal micronized forms of progesterone.

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