scholarly journals EFFECTS OF CONTOMIN (CHLORPROMAZINE) AND GLUCOSE ON THE PROPAGATION OF THE GDVII STRAIN OF MOUSE ENCEPHALOMYELITIS VIRUS IN THE BRAIN TISSUE CULTURE

1955 ◽  
Vol 2 (3) ◽  
pp. 167-175
Author(s):  
YOH NAKAGAWA ◽  
MASAO MARUOKA ◽  
YUKISHIGE KANDA
Keyword(s):  
Tissue Culture ◽  
Brain Tissue ◽  
Encephalomyelitis Virus ◽  
Brain Tissue Culture ◽  
The Brain

Understanding the Physiology of the Blood-Brain Barrier: In Vitro Models

Physiology ◽  
1998 ◽  
Vol 13 (6) ◽  
pp. 287-293 ◽  
Author(s):  
Gerald A. Grant ◽  
N. Joan Abbott ◽  
Damir Janigro
Keyword(s):  
Central Nervous System ◽  
Tissue Culture ◽  
Nervous System ◽  
Blood Brain Barrier ◽  
In Vitro Models ◽  
Brain Barrier ◽  
Blood Brain ◽  
Brain Tissue Culture ◽  
The Brain

Endothelial cells exposed to inductive central nervous system factors differentiate into a blood-brain barrier phenotype. The blood-brain barrier frequently obstructs the passage of chemotherapeutics into the brain. Tissue culture systems have been developed to reproduce key properties of the intact blood-brain barrier and to allow for testing of mechanisms of transendothelial drug permeation.

Slow spontaneous signals from brain tissue culture

1970 ◽  
Vol 26 (1) ◽  
pp. 13-16 ◽  
Author(s):  
A. W. B. Cunningham ◽  
A. E. Hamilton ◽  
M. F. King ◽  
R. R. Rojas-Corona ◽  
G. F. Songster
Keyword(s):  
Tissue Culture ◽  
Brain Tissue ◽  
Brain Tissue Culture

Evoked dopamine release in primary brain tissue culture

1985 ◽  
Vol 13 (1) ◽  
pp. 172-173 ◽  
Author(s):  
OLGA BAROCHOVSKY ◽  
H. F. BRADFORD
Keyword(s):  
Tissue Culture ◽  
Brain Tissue ◽  
Dopamine Release ◽  
Brain Tissue Culture

scholarly journals STUDIES ON EASTERN EQUINE ENCEPHALOMYELITIS

1939 ◽  
Vol 69 (5) ◽  
pp. 675-690 ◽  
Author(s):  
Lester S. King
Keyword(s):  
Brain Tissue ◽  
Guinea Pigs ◽  
Blood Stream ◽  
Serial Sections ◽  
Satisfactory Explanation ◽  
Anatomical Relationship ◽  
Encephalomyelitis Virus ◽  
Random Distributions ◽  
Topographical Analysis ◽  
The Brain

After inoculation with equine encephalomyelitis virus by various routes, guinea pigs were sacrificed at early stages, before symptoms were apparent. The brains were studied histologically, with serial sections; all lesions were noted, and subjected to topographical analysis. Nine cases are presented in detail. With any given mode of inoculation the distribution of lesions varied very widely from one instance to another. In some cases, affected regions bore a striking and definite anatomical relationship to each other. These distributions can be explained only by the assumption that the anatomical pathways played some rôle in the spread of the virus. In other instances lesions were present in areas, the anatomical connections of which were entirely normal. Attention is called to the frequency of lesions in the neocortex, with intact subcortical centers. Such distribution is held to render nerve spread extremely improbable. The only satisfactory explanation of such random distributions is by direct passage of virus from the blood stream into the brain tissue. There is no histological difference between lesions which result from blood spread and those resulting from nerve spread.

Melatonin neutralizes neurotoxicity induced by quinolinic acid in brain tissue culture

2005 ◽  
Vol 39 (3) ◽  
pp. 266-275 ◽  
Author(s):  
Ignacio Vega-Naredo ◽  
Burkhard Poeggeler ◽  
Veronica Sierra-Sanchez ◽  
Beatriz Caballero ◽  
Cristina Tomas-Zapico ◽  
...  
Keyword(s):  
Tissue Culture ◽  
Brain Tissue ◽  
Quinolinic Acid ◽  
Brain Tissue Culture

scholarly journals AUTOSENSITIZATION REACTION IN VITRO

1962 ◽  
Vol 116 (4) ◽  
pp. 467-476 ◽  
Author(s):  
Hilary Koprowski ◽  
Mario V. Fernandes
Keyword(s):  
Tissue Culture ◽  
Lymph Node ◽  
Guinea Pig ◽  
Inbred Strain ◽  
Brain Tissue ◽  
Glial Cells ◽  
Agglutination Test ◽  
Lymph Node Cells ◽  
Brain Tissue Culture

Lymph node cells were obtained from an inbred strain of Lewis rats injected with guinea pig cord tissue in Freund's adjuvant. These cells, when added to tissue culture monolayers of puppy brain, aggregated on or around the glial elements. This reaction, called contactual agglutination, was followed by the specific destruction of glial cells, leaving cultures consisting only of fibroblasts. No such reaction was noted when lymph node cells obtained either from normal rats or those injected with adjuvant alone were used. Absorption of serum obtained from rats injected with guinea pig cord tissue by non-sensitized lymph node cells made them reactive in brain tissue culture. The contactual agglutination test seems to provide an opportunity for investigation of sensitization reaction in tissue culture systems.

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