Trends in seasonal influenza vaccine coverage of target groups in France, 2006/07 to 2015/16: Impact of recommendations and 2009 influenza A(H1N1) pandemic

Background and aims Seasonal influenza vaccination (SIV) uptake (SIVU) rates in France are below target. We (i) describe trends in French SIVU over 10 consecutive seasons among different target groups and (ii) examine the effects of the 2009 influenza A(H1N1) pandemic and the publication of new SIV recommendations in 2011 and 2013. Methods Our study was based on records of vaccines delivered in community pharmacies for a permanent, representative sample of 805,000 beneficiaries of the French National Health Insurance Fund. For the first objective, we analysed SIVU rate trends among ≥ 65 year olds as well as among < 65 year olds with each of the following conditions: diabetes, respiratory, cardiovascular, neuromuscular, or chronic liver disease. For the second goal, we computed segmented log-binomial regression analyses. Results After the 2009 pandemic, except for the target group with liver diseases, where the difference was not statistically significant, SIVU fell significantly in all groups during the 2010/11 season, remaining relatively stable until 2015/16 in groups not targeted by new recommendations. Crude SIVU rates in 2015/16 were 48% (43,950/91,794) for ≥ 65 year olds and between 16% (407/2,565) and 29% (873/3,056) for < 65 year olds depending on their condition. SIVU increased modestly after new recommendations were published, but only in patients newly eligible for a free vaccine voucher. Conclusions Our results suggest: (i) a prolonged confidence crisis in SIV, initially impelled by the 2009 pandemic vaccination campaign; (ii) that new recommendations are ineffective without additional measures. Interventional research in this field is a priority.

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Lessons from the Past: Comparison of the Disease Burden of the Influenza A (H1N1) Pandemic 2009-10 and Seasonal Influenza 2010-2019 in the United States

10.21203/rs.3.rs-198743/v1 ◽

2021 ◽

Author(s):

James A Koziol

Keyword(s):

United States ◽

Influenza A ◽

Disease Burden ◽

Seasonal Influenza ◽

The United States ◽

H1n1 Pandemic ◽

Elderly Adults ◽

The Past ◽

Medical Visits ◽

Influenza A H1n1

Abstract Background Annual influenza outbreaks constitute a major public health concern, both in the United States and worldwide. Comparisons of the health burdens of outbreaks might lead to the identification of specific at-risk populations, for whom public health resources should be marshaled appropriately and equitably. Methods We examined the disease burden of the 2009-10 influenza A (H1N1) pandemic relating to illnesses, medical visits, hospitalizations, and mortality, compared to influenza seasons 2010 to 2019, in the United States, as compiled by the Centers for Disease Control. Results With regard to seasonal influenza, rates of illnesses and medical visits were highest in infants aged 0–4 years, followed by adults aged 50–64 years. Rates of hospitalizations and deaths evinced a starkly different pattern, both dominated by elderly adults aged 65 and over. Youths aged 0 to 17 years were especially adversely affected by the H1N1 pandemic relative to hospitalizations and mortality compared to seasonal influenza; but curiously the opposite pattern was observed in elderly adults (aged 65 and older). Conclusions The disease burden of the 2009-10 influenza A pandemic was strikingly unlike that observed in the subsequent influenza seasons 2010 to 2019, in the United States: the past did not predict the future.

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Trends in influenza vaccination behaviours – results from the CoPanFlu cohort, France, 2006 to 2011

Eurosurveillance ◽

10.2807/1560-7917.es2013.18.45.20628 ◽

2013 ◽

Vol 18 (45) ◽

Cited By ~ 20

Author(s):

A L Caille-Brillet ◽

J Raude ◽

N Lapidus ◽

X De Lamballerie ◽

F Carrat ◽

...

Keyword(s):

Risk Factors ◽

Influenza Vaccination ◽

Pandemic Influenza ◽

Influenza A ◽

Seasonal Influenza ◽

General Trend ◽

Vaccine Coverage ◽

Risk Groups ◽

Influenza A H1n1 ◽

Negative Effect

Controversies over the effectiveness and safety of the pandemic influenza A(H1N1)pdm09 vaccine in 2009/10 may have altered the influenza vaccination coverage in France after the pandemic season. The purpose of this study was to determine whether the pandemic affected seasonal influenza vaccination behaviours in the general population by analysing vaccination behaviours from 2006/07 to 2011/12 among the 1,451 subjects of the Cohort for Pandemic Influenza (CoPanFlu) France. We found that vaccination behaviours in 2010/11 and 2011/12 significantly differed from behaviours before the pandemic, with the notable exception of the targeted risk groups for seasonal influenza-related complications. Among the population with no risk factors, the post-pandemic influenza vaccine coverage decreased, with people aged 15 to 24 years and 45 to 64 years being most likely to abandon vaccination. Therefore, this study documents a moderate negative effect of the 2009/10 pandemic episode on vaccination behaviours in the French metropolitan population that was apparent also in the following two seasons. Moreover, it does not exclude that the general trend of reduced vaccination has also affected certain targeted groups at high risk for complications.

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Risk groups and other target groups – preliminary ECDC guidance for developing influenza vaccination recommendations for the season 2010-11

Eurosurveillance ◽

10.2807/ese.15.12.19525-en ◽

2010 ◽

Vol 15 (12) ◽

Cited By ~ 1

Author(s):

H Nokleby ◽

A Nicoll

Keyword(s):

Influenza Vaccination ◽

Influenza A ◽

Seasonal Influenza ◽

H1n1 Virus ◽

Risk Groups ◽

Evidence Based ◽

Target Groups ◽

Rigorous Approach ◽

Vaccination Recommendations ◽

Influenza A H1n1

Providing guidance on risk and target groups for seasonal influenza immunisation is difficult for the 2010-11 season since there is no experience with the new influenza A(H1N1) virus in its seasonal form. Arguments exist for offering immunisation to people with chronic illness and older people, and also for other risk and target groups including pregnant women. A more rigorous approach is being developed to produce annual evidence-based guidance on risk and target groups for influenza vaccination.

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Lessons from the Past: Methodological Issues Arising from Comparison of the Disease Burden of the Influenza A (H1N1) Pandemic 2009-10 and Seasonal Influenza 2010-2019 in the United States

Journal of Infectious Diseases and Epidemiology ◽

10.23937/2474-3658/1510218 ◽

2021 ◽

Vol 7 (7) ◽

Author(s):

Koziol James A ◽

Schnitzer Jan E

Keyword(s):

United States ◽

Influenza A ◽

Disease Burden ◽

Seasonal Influenza ◽

The United States ◽

H1n1 Pandemic ◽

Methodological Issues ◽

The Past ◽

Influenza A H1n1

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Seasonal influenza vaccination uptake in Quebec, Canada, 2 years after the influenza A(H1N1) pandemic

American Journal of Infection Control ◽

10.1016/j.ajic.2014.01.006 ◽

2014 ◽

Vol 42 (5) ◽

pp. e55-e59 ◽

Cited By ~ 20

Author(s):

Eve Dubé ◽

Dominique Gagnon ◽

Marilou Kiely ◽

Fannie Defay ◽

Maryse Guay ◽

...

Keyword(s):

Influenza Vaccination ◽

Influenza A ◽

Seasonal Influenza ◽

H1n1 Pandemic ◽

Seasonal Influenza Vaccination ◽

Vaccination Uptake ◽

Influenza A H1n1

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(P1-82) Implementation of an Active Vaccination Strategy Increased the Pandemic Influenza A (H1N1) 2009 Vaccine Coverage among Swedish Children

Prehospital and Disaster Medicine ◽

10.1017/s1049023x11004146 ◽

2011 ◽

Vol 26 (S1) ◽

pp. s125-s125

Author(s):

M. Omberg

Keyword(s):

Vaccination Coverage ◽

Pandemic Influenza ◽

Influenza A ◽

Vaccine Coverage ◽

Vaccination Campaign ◽

Vaccination Strategy ◽

Care Providers ◽

Active Vaccination ◽

Influenza A H1n1 ◽

Passive Vaccination

IntroductionThe European Center for Disease Control and Prevention (ECDC) identified young children as a group at higher risk of developing severe pandemic influenza A (H1N1) 2009 infection compared with the general population. Since children have high attack rates and seem essential in augmenting local outbreaks of influenza, vaccination of children was an important objective in the Swedish pandemic influenza A (H1N1) 2009 vaccination campaign. Children < 13 years of age were recommended to take two doses of the pandemic vaccine (Pandemrix®).ObjectiveThe objective of this study was to compare the vaccination coverage among children 1–12 years of age in different councils in the County of Jämtland, Sweden that either implemented an active advocating or a passive vaccination strategy. The active strategy included direct information to parents promoting vaccination, individual appointments, collaboration between different care providers, and visits of vaccination teams to day care centers and schools, whereas no specific measures, except general information in press and media, were undertaken in councils using a passive approach.MethodsAll pandemic vaccinations in the County of Jämtland were registered in a Web-based registration software system. Vaccine coverage was determined by comparing the actual number of children residing in different councils with the number of vaccinated children.ResultsA total of 4,162 of 6,000 children (69.3%) residing in councils using an active vaccination strategy were vaccinated compared with 5,059 of 9,373 children (53.9%) living in councils using a passive vaccination strategy (p < 0.0001)ConclusionsImplementation of an active advocating vaccination strategy during the Swedish pandemic influenza A (H1N1) 2009 vaccination campaign resulted in a significantly higher vaccination coverage rate compared with a passive vaccination strategy.

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Neurologic and Muscular Complications of the 2009 Influenza A (H1N1) Pandemic

Yearbook of Neurology and Neurosurgery ◽

10.1016/j.yneu.2011.05.034 ◽

2011 ◽

Vol 2011 ◽

pp. 129-130

Author(s):

A. Verma

Keyword(s):

Influenza A ◽

H1n1 Pandemic ◽

Influenza A H1n1

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Diagnostic Wrinkles Anticipated in Novel Influenza A (H1N1) Pandemic

Family Practice News ◽

10.1016/s0300-7073(09)70654-1 ◽

2009 ◽

Vol 39 (15) ◽

pp. 22

Author(s):

BRUCE JANCIN

Keyword(s):

Influenza A ◽

H1n1 Pandemic ◽

Influenza A H1n1 ◽

Novel Influenza A

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Progression and Trends in Virus from Influenza A to COVID-19: An Overview of Recent Studies

Viruses ◽

10.3390/v13061145 ◽

2021 ◽

Vol 13 (6) ◽

pp. 1145

Author(s):

Hakimeh Baghaei Daemi ◽

Muhammad Fakhar-e-Alam Kulyar ◽

Xinlin He ◽

Chengfei Li ◽

Morteza Karimpour ◽

...

Keyword(s):

Influenza A ◽

H1n1 Virus ◽

World Health ◽

H1n1 Pandemic ◽

Global Pandemic ◽

First Case ◽

Influenza A H1n1 ◽

The World ◽

Novel Coronavirus ◽

Health Organization

Influenza is a highly known contagious viral infection that has been responsible for the death of many people in history with pandemics. These pandemics have been occurring every 10 to 30 years in the last century. The most recent global pandemic prior to COVID-19 was the 2009 influenza A (H1N1) pandemic. A decade ago, the H1N1 virus caused 12,500 deaths in just 19 months globally. Now, again, the world has been challenged with another pandemic. Since December 2019, the first case of a novel coronavirus (COVID-19) infection was detected in Wuhan. This infection has risen rapidly throughout the world; even the World Health Organization (WHO) announced COVID-19 as a worldwide emergency to ensure human health and public safety. This review article aims to discuss important issues relating to COVID-19, including clinical, epidemiological, and pathological features of COVID-19 and recent progress in diagnosis and treatment approaches for the COVID-19 infection. We also highlight key similarities and differences between COVID-19 and influenza A to ensure the theoretical and practical details of COVID-19.

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