scholarly journals Determination of the Parameters Effective in Traffic Accidents with Fixed Objects by Factorial Design Method

Author(s):  
Ali Akgüngör ◽  
Merve Burçin Cenikli
Toxics ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 111
Author(s):  
Maria Mihăilescu ◽  
Adina Negrea ◽  
Mihaela Ciopec ◽  
Petru Negrea ◽  
Narcis Duțeanu ◽  
...  

Gold is one of the precious metals with multiple uses, whose deposits are much smaller than the global production needs. Therefore, extracting maximum gold quantities from industrial diluted solutions is a must. Am-L-GA is a new material, obtained by an Amberlite XAD7-type commercial resin, functionalized through saturation with L-glutamic acid, whose adsorption capacity has been proved to be higher than those of other materials utilized for gold adsorption. In this context, this article presents the results of a factorial design experiment for optimizing the gold recovery from residual solutions resulting from the electronics industry using Am-L-GA. Firstly, the material was characterized using atomic force microscopy (AFM), to emphasize the material’s characteristics, essential for the adsorption quality. Then, the study showed that among the parameters taken into account in the analysis (pH, temperature, initial gold concentration, and contact time), the initial gold concentration in the solution plays a determinant role in the removal process and the contact time has a slightly positive effect, whereas the pH and temperature do not influence the adsorption capacity. The maximum adsorption capacity of 29.27 mg/L was obtained by optimizing the adsorption process, with the control factors having the following values: contact time ~106 min, initial Au(III) concentration of ~164 mg/L, pH = 4, and temperature of 25 °C. It is highlighted that the factorial design method is an excellent instrument to determine the effects of different factors influencing the adsorption process. The method can be applied for any adsorption process if it is necessary to reduce the number of experiments, to diminish the resources or time consumption, or for expanding the investigation domain above the experimental limits.


2013 ◽  
Vol 16 (5) ◽  
pp. 1122-1127 ◽  
Author(s):  
Lindiane Bieseki ◽  
Francine Bertell ◽  
Helen Treichel ◽  
Fabio G. Penha ◽  
Sibele B. C. Pergher

2021 ◽  
Vol 11 (5) ◽  
pp. 13089-13101

In this study, a sustainable HPLC-UV-DAD method was developed and validated for the determination of allopurinol in tablets and optimization of the dissolution test using factorial design. The separation of the analyte from the sample matrix was achieved in 3.01 minutes in a C8 column (4.6 mm X 150 mm X 5 μm), using mobile phase 0.1 mol L-1 HCl (25%) + ethanol (50%) + ultrapure water (25%) by UV detection at 249 nm. The method presented satisfactory analytical parameters of validation (specificity, selectivity, linearity, stability, precision, accuracy, and robustness), showing no matrix effects. The dissolution test was optimized by complete factorial design 23 and, the optimal conditions were: HCl 0.001 mol L-1, apparatus II (paddle) and 75 rpm. The analytical procedures and dissolution tests were applied to allopurinol tablets marketed in Bahia, Brazil, to evaluate the dissolution studies. The pharmaceuticals had similar dissolution profiles and first-order dissolution kinetics. This new and sustainable HPLC-UV-DAD method is friendly to the environment and can be used for the routine pharmaceutical analysis of allopurinol in fixed dosage forms.


2021 ◽  
Vol 1 (1) ◽  
pp. 15-21
Author(s):  
Pande Putu Dwi Novigga Artha

Density of Surabaya city affects the physical and psychological health of the people. Productive activities accompanied by a dense environment mean that people rarely have time to exercise. To increase the awareness and interest of the people of the city of Surabaya to exercise, it is necessary to have a sports facility with a special approach. Biophilic theory, especially the natural shapes and form approach, can be a solution to these problems. The return of nature's essence into the building can provide positive benefits for human physical and physical health. Previous research has discussed the determination of fitness center design criteria with the natural shapes and forms approach in Surabaya. In this follow-up journal, we will discuss the final result or application of the design criteria into an architectural work. The design method used is the force based framework method. The force in the design of this building in addition to the surrounding natural environment is the natural perception of the community which is transformed into architectural forms. It aims to increase interest in training and restoring the user's physical and psychological health without having to go far out of town to look for nature.


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