scholarly journals Conceptual design and optimization of self microemulsifying drug delivery systems for dapsone by using Box-Behnken design

2021 ◽  
Vol 25(2) (25(2)) ◽  
pp. 179-195
Author(s):  
Jayashri MAHORE-Aniket SHELAR-Sanjeevani DESHKAR
Keyword(s):  
Drug Delivery ◽  
Conceptual Design ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Box Behnken Design ◽  
Design And Optimization

Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

2021 ◽  
Vol 61 ◽  
pp. 102241
Author(s):  
Kantaporn Kheawfu ◽  
Surachai Pikulkaew ◽  
Thomas Rades ◽  
Anette Müllertz ◽  
Louise von Gersdorff Jørgensen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Clove Oil ◽  
Design And Optimization

Formulation by design of felodipine loaded liquid and solid self nanoemulsifying drug delivery systems using Box–Behnken design

2013 ◽  
Vol 40 (10) ◽  
pp. 1358-1370 ◽  
Author(s):  
Samridhi Verma ◽  
Sandeep Kumar Singh ◽  
Priya Ranjan Prasad Verma ◽  
Mohd Neyaz Ahsan
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Box Behnken Design

scholarly journals Design and optimization of self-nanoemulsifying drug delivery systems (SNEDDS) for enhanced dissolution of gemfibrozil

2012 ◽  
Vol 431 (1-2) ◽  
pp. 161-175 ◽  
Author(s):  
Ana Maria Sierra Villar ◽  
Beatriz Clares Naveros ◽  
Ana Cristina Calpena Campmany ◽  
Monserrat Aróztegui Trenchs ◽  
Coloma Barbé Rocabert ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Design And Optimization ◽  
Enhanced Dissolution

Design and optimization of MEMS based piezoelectric actuator for drug delivery systems

2019 ◽  
Vol 26 (5) ◽  
pp. 1671-1679 ◽  
Author(s):  
K. Srinivasa Rao ◽  
Md. Hamza ◽  
P. Ashok Kumar ◽  
K. Girija Sravani
Keyword(s):  
Drug Delivery ◽  
Piezoelectric Actuator ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Design And Optimization

scholarly journals Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform

2021 ◽  
Vol 2021 ◽  
pp. 1-21
Author(s):  
Pengyu Gao ◽  
Dan Zou ◽  
Ansha Zhao ◽  
Ping Yang
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Cell Function ◽  
Survival Rates ◽  
Circulatory System ◽  
Delivery Systems ◽  
Therapeutic Effects ◽  
Design And Optimization ◽  
Targeting Efficiency ◽  
Blood Circulatory System

Achievement of high targeting efficiency for a drug delivery system remains a challenge of tumor diagnoses and nonsurgery therapies. Although nanoparticle-based drug delivery systems have made great progress in extending circulation time, improving durability, and controlling drug release, the targeting efficiency remains low. And the development is limited to reducing side effects since overall survival rates are mostly unchanged. Therefore, great efforts have been made to explore cell-driven drug delivery systems in the tumor area. Cells, particularly those in the blood circulatory system, meet most of the demands that the nanoparticle-based delivery systems do not. These cells possess extended circulation times and innate chemomigration ability and can activate an immune response that exerts therapeutic effects. However, new challenges have emerged, such as payloads, cell function change, cargo leakage, and in situ release. Generally, employing cells from the blood circulatory system as cargo carriers has achieved great benefits and paved the way for tumor diagnosis and therapy. This review specifically covers (a) the properties of red blood cells, monocytes, macrophages, neutrophils, natural killer cells, T lymphocytes, and mesenchymal stem cells; (b) the loading strategies to balance cargo amounts and cell function balance; (c) the cascade strategies to improve cell-driven targeting delivery efficiency; and (d) the features and applications of cell membranes, artificial cells, and extracellular vesicles in cancer treatment.

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