scholarly journals Features of the action of anxiolytics of natural and synthetic origin on inbred and outbred mice

Author(s):  
O. N. Savanets ◽  
E. V. Kravchenko ◽  
P. T. Petrov
2015 ◽  
Vol 45 (7) ◽  
pp. 1319-1326 ◽  
Author(s):  
Mariana de Araújo Etchepare ◽  
Juliano Smanioto Barin ◽  
Alexandre José Cichoski ◽  
Eduardo Jacob-Lopes ◽  
Roger Wagner ◽  
...  

The consumption of probiotics is constantly growing due to the numerous benefits conferred on the health of consumers. In this context, Microencapsulation is a technology that favors the viability of probiotic cultures in food products, mainly by the properties of protection against adverse environmental conditions and controlled release. Currently there are different procedures for microencapsulation using polymers of various types of natural and synthetic origin. The use of sodium alginate polymers is one of the largest potential application in the encapsulation of probiotics because of their versatility, biocompatibility and toxicity exemption. The aim of this review is to present viable encapsulation techniques of probiotics with alginate, emphasizing the internal ionic gelation and external ionic gelation, with the possibility of applying, as well as promising for improving these techniques.


Polymers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1114 ◽  
Author(s):  
Paola Franco ◽  
Iolanda De Marco

Polyvinylpyrrolidone (PVP) is a hydrophilic polymer widely employed as a carrier in the pharmaceutical, biomedical, and nutraceutical fields. Up to now, several PVP-based systems have been developed to deliver different active principles, of both natural and synthetic origin. Various formulations and morphologies have been proposed using PVP, including microparticles and nanoparticles, fibers, hydrogels, tablets, and films. Its versatility and peculiar properties make PVP one of the most suitable and promising polymers for the development of new pharmaceutical forms. This review highlights the role of PVP in drug delivery, focusing on the different morphologies proposed for different polymer/active compound formulations. It also provides detailed information on active principles and used technologies, optimized process parameters, advantages, disadvantages, and final applications.


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