scholarly journals Histopathological spectrum of lesions in nephrectomy specimens: Five years’ experience in a private lab.

2021 ◽  
Vol 28 (12) ◽  
pp. 1824-1828
Author(s):  
Shireen Hamid ◽  
Shazia Aslam ◽  
Hafiza Azka Iqbal ◽  
Hafsa Tariq ◽  
Rafique Cheema ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Malignant Tumor ◽  
Clear Cell ◽  
Renal Diseases ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Cell Renal Cell Carcinoma ◽  
Neoplastic Lesion ◽  
Time Period ◽  
Study Setting

Objective: The aim of this study was to evaluate the histopathological changes in the nephrectomy specimens. Study Design: Retrospective study. Setting: Private Lab, Located in Faisalabad. Period: January 2015 to December 2019. Material & Methods: A total of 113 cases were included in the study. In this study paraffin blocks and previous slides along with clinical data were analyzed according to standard protocols. Patient age, sex and histological diagnosis were noted and compared. Results: In this study we analyzed 113 cases, received during a five year time period. Out of which 60 (53%) were males and 53 (47%) were females. Most common age group ranges from 51 to 60 years and the least common affected group was 71 to 80 years. The neoplastic cases were 66 (58%) and nonneoplastic cases were 47(42%). Neoplastic were further sub- divided in to 3(5%) benign cases and 63(95%) malignant cases.  Most common neoplastic lesion was clear cell renal cell carcinoma, 49 (74%) cases and most common non- neoplastic condition was chronic pyelonephritis, 37 (78%) cases. Conclusion: Nephrectomy is the ultimate surgical procedure for the treatment of renal diseases. The 5th to 6th decade is the most common age group of patients affected by non- neoplastic conditions leading to non-functioning kidney. Malignant tumor like clear cell carcinoma is the most common malignant tumor in our society. Early clinical, radiological and histopathological diagnosis of renal diseases will help out patients for proper management. Thus every nephrectomy specimen should be evaluated through clinico –pathological correlation.

scholarly journals Percutaneous Biopsy under Simultaneous Ultrasound and Computer Tomography Guidance in Diagnosis of Isolated Pancreatic Metastasis of Clear Cell Renal Cell Carcinoma

2019 ◽  
pp. 290-294
Author(s):  
Chorąży M ◽  
Kubera A ◽  
Wodołażski A
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Pancreatic Metastasis ◽  
Cancer Site ◽  
Histopathological Diagnosis ◽  
Cell Renal Cell Carcinoma ◽  
Guided Biopsy

Cancers of the kidney are a various group of tumors, most of which are of epithelial origin and malignant. Renal cell carcinoma (RCC) classically referred to as clear cell carcinoma is the most common kidney cancer (70- 80% of all kidney cancers). The most common primary cancer site resulting in pancreatic metastases is liver, followed by colorectal cancer, melanoma, breast cancer, lung carcinoma and sarcoma. 65 year old man six years after nephrectomy due to clear cell renal cell carcinoma (ccRCC), attended regular abdominal CT examination, which revealed 28.9 mm focal lesion located in pancreatic tail. No other pathological lesions were detected. Patient underwent US guided biopsy preceded by CT pre-biopsy planning. Histopathological analysis of the obtained material confirmed clear cell carcinoma. The authors being aware of other than renal possible sites of clear cell carcinoma origin, additional tests such as membranous immunoreactivity with renal cell carcinoma (RCC), and immunohistochemical staining applied to identify the cellular origin and confirm the renal origin of the metastasis. This innovative, combined method of US guided biopsy supported by CT pre-biopsy planning can be helpful in the diagnosis of atypically located metastases of RCC. Our described case shows that in contrast to other well-known biopsy methods, our assay enables to obtain material for complete histopathological diagnosis and consequently start treatment. Moreover, presented method is based on diagnostic tools that are routinely available in every hospital such as US and CT. The only required modification is the installation of programme that enables to upload CT images containing marked planned needle path to the biopsy room, and simultaneous display of both - static CT image and US image performed in real time.

scholarly journals Rare Case of Clear Cell Renal Cell Carcinoma Metastasizing to Contralateral Kidney and Ipsilateral Parotid more than five Years following Nephrectomy

2019 ◽  
Vol 23 (2) ◽  
pp. 108-111
Author(s):  
Guy Sydney ◽  
Kalliopi Ioakim ◽  
Nayia Kara ◽  
George Pantelas
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Rare Case ◽  
Clear Cell ◽  
Histopathological Diagnosis ◽  
Cell Renal Cell Carcinoma ◽  
Contralateral Kidney ◽  
History Of ◽  
Patient’S History

Summary Backgroung/Aim: Salivary gland malignancies are rare, with only a fraction due to metastases. We report a rare case of the Clear Cell Renal Cell Carcinoma (CCRCC), a subtype of the Renal Cell Carcinoma (RCC), metastasizing to the parotid gland more than five years following nephrectomy. Case report: A 75-year-old female presented with a unilateral left parotid mass that was growing over the period of 18 months. After clinical and laboratory examinations, the patient underwent left partial superficial parotidectomy with preservation of the facial nerve. The significance of the patient’s history of the CCRCC was pivotal to the histopathological diagnosis of a metastatic CCRCC to the parotid. Conclusions: The unpredictable nature of the RCC results in the need for a long period of follow-up, as well as having a high degree of suspicion of metastasis in a patient presenting with a medical history of the RCC and a parotid mass.

638: Macroscopic Tumor Necrosis is a Prognostic Indicator for Non-Metastatic Clear Cell Renal Cell Carcinoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 214-214
Author(s):  
Sung Kyu Hong ◽  
Byung Kyu Han ◽  
In Ho Chang ◽  
June Hyun Han ◽  
Ji Hyung Yu ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Tumor Necrosis ◽  
Clear Cell ◽  
Prognostic Indicator ◽  
Cell Renal Cell Carcinoma ◽  
Macroscopic Tumor

Rare localization of renal cell carcinoma metastases in the paranasal sinuses and breast: a case report

2019 ◽  
Vol 22 (6) ◽  
pp. 13-22
Author(s):  
E. V. Kryaneva ◽  
N. A. Rubtsova ◽  
A. V. Levshakova ◽  
A. I. Khalimon ◽  
A. V. Leontyev ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Paranasal Sinuses ◽  
Renal Cell ◽  
Clinical Case ◽  
Clear Cell ◽  
Malignant Tumors ◽  
Metastatic Potential ◽  
Cell Renal Cell Carcinoma ◽  
Metastatic Lesions

This article presents a clinical case demonsratinga high metastatic potential of clear cell renal cell carcinoma combined with atypical metastases to breast and paranasal sinuses. The prevalence of metastatic lesions to the breast and paranasal sinuses in various malignant tumors depending on their morphological forms is analyzed. The authors present an analysis of data published for the last 30 years. The optimal diagnostic algorithms to detect the progression of renal cell carcinoma and to evaluate the effectiveness of the treatment are considered.

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