scholarly journals Bilateral corneal ulcer and hypovitaminosis A: a case report

Author(s):  
Chaimae Khodriss ◽  
Ahmed Bennis ◽  
Fouad Chraibi ◽  
Meriem Abdellaoui ◽  
Idriss Benatiya Andaloussi

Vitamin A is a fat-soluble discovered in 1913. Hypo-vitaminosis A can cause blindness by various mechanisms. The aim of this case report is to emphasize the severity of Vitamin A deficiency and its local consequences on the eyes causing corneal ulcerations, abscess and even blindness.

Author(s):  
M.P. Hartley ◽  
R.M. Kirberger ◽  
M. Haagenson ◽  
L. Sweers

Vitamin A deficiency is described in captive lions. Ante mortem diagnosis can either be made by serum analysis or liver biopsy, both of which may be problematic. This study utilised magnetic resonance imaging to identify vitamin A deficiency in lions with relatively mild clinical signs, which could otherwise be attributed to numerous other neurological conditions. Magnetic resonance imaging is a non-invasive, reliable diagnostic tool to demonstrate pathology typically associated with this condition. To accommodate varying lion ages and sizes, a number of cranium and brain measurements were compared with that of the maximum diameter of the occular vitreous humor. Occular ratios of the tentorium cerebelli osseum and occipital bone were most reliable in diagnosing the thickened osseous structures characteristic of hypovitaminosis A. The ratio of maximum : minimum dorsoventral diameter of the C1 spinal cord was also of value.


1987 ◽  
Vol 71 (10) ◽  
pp. 787-790 ◽  
Author(s):  
M. O'Donnell ◽  
J. F. Talbot

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255924
Author(s):  
Martin J. Schmidt ◽  
Gerhard Steenkamp ◽  
Peter Caldwell ◽  
Klaus Failing ◽  
Robert M. Kirberger

Captive cheetahs often demonstrate a high incidence of diseases in which vitamin A imbalances are implicated. These can occur even under controlled and optimised feeding regimens, which is why surveillance of vitamin A status is mandatory in the successful health management of cheetahs. Serum levels of the vitamin do not reflect the true vitamin A status and liver tissue analysis is rather impractical for routine application in large felids. A biomarker for evaluating overt and subclinical vitamin A deficiency in cheetahs is needed. This study evaluates whether increased calvarial bone thickness can be detected on routine skull radiographs of vitamin A deficient cheetahs compared to unaffected animals, and secondly, evaluates whether there is increased bone thickness in clinically sound captive cheetahs in general compared to wild-living controls. Bone thickness in the neuro- and splanchnocranium was measured in 138 skull radiographs. Significant thickening of the parietal bones was found in latero-lateral radiographs of immature cheetahs (< 12 months) with vitamin A deficiency. This finding may allow a presumptive diagnosis of hypovitaminosis A in immature cheetahs. A general difference in skull thickness between free-living and captive cheetahs was not found.


2015 ◽  
Vol 6 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Emma Duignan ◽  
Paul Kenna ◽  
Rosemarie Watson ◽  
Susan Fitzsimon ◽  
Donal Brosnahan

We describe the cases of 2 autistic children with ophthalmic and systemic manifestations of vitamin A deficiency due to food faddism. Although vitamin A deficiency is common in the developing world, reports in developed societies are rare. Our patients presented over a 1-year period. The patients were 14 and 13 years old at the time of presentation and were both found to have marked features of vitamin A deficiency related to unusual dietary habits. Anterior segment signs of xerophthalmia were present in both patients. In addition, patient 1 showed evidence of a rod-predominant retinopathy, which resolved with vitamin A supplementation. Due to its rare occurrence, hypovitaminosis A must be highlighted and anticipated in this cohort.


2021 ◽  
Vol 25 (1) ◽  
pp. 17-19
Author(s):  
Ka-Wai Kam ◽  
Anita LW Li ◽  
Chun-Yue Mak ◽  
Bosco HM Ma ◽  
Alvin L Young

2009 ◽  
Vol 20 (3) ◽  
pp. 397-400 ◽  
Author(s):  
Christine Stroh ◽  
Christian Weiher ◽  
Ulrich Hohmann ◽  
Frank Meyer ◽  
Hans Lippert ◽  
...  

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