Diabetes is a serious chronic disease that occurs because the pancreas does not produce enough insulin. Quality of life is very important to get serious attention, because the quality of life is something that is closely related to a person's health condition, the severity of the disease, the duration of healing, and can even aggravate the condition of the disease to death if a person has a poor quality of life. This study aims to determine the relationship between family support and stress with the quality of life of the elderly with type II diabetes mellitus in the Sekupang Health Center, Batam City, 2020. Data collection usedthe questionnaire brought by the researcher to the population elderly people with Type II Diabetes Mellitusin Batam City in 2020. The inclusion criteria are elderly who are willing to be respondents, elderly who suffer from Diabetes Mellitus Type II, elderly who are ≥60 years old, elderly who can communicate well, and elderly who do not experience cognitive impairment. Research respondents involved in this study were 64 respondents. Chi-Square statistical test results obtained value (p value = 0.000 <0.05), indicating that H0 is rejected and Ha is accepted. Conclusion: there is a significant relationship between family support and stress with the quality of life of the elderly with type II diabetes mellitus in the Sekupang Health Center, Batam City, 2020.