scholarly journals Synthesis, characterization and photostability study of triazole derivatives

2021 ◽  
Vol 9 (2) ◽  
pp. 066-072
Author(s):  
Shahad Muhammad ◽  
Ahmed Ahmed
Keyword(s):  
Schiff Base ◽  
Infrared Spectroscopy ◽  
1H Nmr ◽  
13C Nmr ◽  
Uv Light ◽  
Alkyl Halide ◽  
Triazole Ring ◽  
Phenacyl Bromide ◽  
Heterocyclic Derivative ◽  
Triazole Derivatives

heterocyclic derivative contain triazole ring was synthesized and characterized the product and their structures by infrared spectroscopy, 1H-NMR, 13C-NMR and instrumental techniques. Compound (4) was synthesized by reacting of Schiff base (3) with an three moles of alkyl halide (p-phenyl phenacyl bromide). Final product played an important role in photostabilizer of polymer (PS), and showed the activity as a photostabilizer when exposed to UV light (300 hours).

Synthesis and Spectral Characterization of New S-Alkylated 1,2,4-Triazoles as Potential Biological Agents

2017 ◽  
Vol 68 (10) ◽  
pp. 2436-2439
Author(s):  
Stefania Felicia Barbuceanu ◽  
Laura Ileana Socea ◽  
Constantin Draghici ◽  
Elena Mihaela Pahontu ◽  
Theodora Venera Apostol ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Spectral Data ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Ethyl Bromide ◽  
Spectral Characterization ◽  
Basic Medium ◽  
Phenacyl Bromide

In the work we presented the behavior of 5-(4-(4-X-phenylsulfonyl)phenyl)-4-(n-propyl)-2H-1,2,4-triazole-3(4H)-thiones (X= Cl or Br) with some alkylation agents. Thus, new S-alkylated 1,2,4-triazole derivatives were synthesized by reaction of the corresponding 1,2,4-triazole-3-thione derivatives with different �-halogenated compounds (ethyl bromide, ethyl chloroacetate or phenacyl bromide), in basic medium. The structures of synthesized compounds were elucidated by spectral data (1H-NMR, 13C-NMR, mass spectrometry) and elemental analysis.

scholarly journals SYNTHESIS AND BIOLOGICAL ACTIVITIES EVALUATION OF SOME NEW SPIRO 1,2,4-TRIAZOLE DERIVATIVES HAVING SULFONAMIDE MOIETY

2015 ◽  
Vol 23 (23) ◽  
pp. 49-59
Author(s):  
Hany M. Dalloul ◽  
Khaled El-nwairy ◽  
Ali Z. Shorafa ◽  
Ahmed Abu Samaha
Keyword(s):  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Sulfonic Acid ◽  
Spectroscopic Data ◽  
Biological Activities ◽  
Cyclic Ketones ◽  
Triazole Derivatives ◽  
Toluene Sulfonic Acid

A series of new spiro 1,2,4-triazoles V-IXa-j were synthesized by the reaction of appropriate amidrazones IV with cyclic ketones in the presence of p-toluene sulfonic acid as a catalyst. The structures of the synthesized compounds have been confirmed by the elemental analysis and spectroscopic data (IR, 1H NMR, 13C NMR and MS). The microbial features of the synthesized compounds were studied using well-established methods from the literature.

scholarly journals Synthesis and Characterization of some new Formazan Derivatives from 2-Amino-4-Hydroxy-6-Methyl Pyrimidine and Study the Biological Activity (Anti-Bacteria and Anti-Cancer)

2020 ◽  
Vol 11 (01) ◽  
pp. 53-59
Author(s):  
Shaimaa Adnan ◽  
Abdullah Shakir
Keyword(s):  
Fourier Transform ◽  
Biological Activity ◽  
Schiff Base ◽  
Infrared Spectroscopy ◽  
13C Nmr ◽  
Synthesis And Characterization ◽  
Compound A ◽  
Anti Cancer ◽  
Base Derivative

This study involves a synthesis of some formazan derivatives starting from react chloro acetyl chlorid with 2-amino-4-hydroxy-6-methyl pyrimidine to gate compound (a), (a) react with hydrazine hydrate to give compound (b) also (b) react with 3-4-dimethoxy benzaldehyd to product Schiff base derivative (c) then (c) react with deferent amin derivatives to get formazan derivatives. All these compounds characterized by 13C-NMR, fourier transform infrared spectroscopy (FTIR), 1HMNR. After that, we study the biological activity for all formazan derivatives toward two different kinds of bacteria and anti-cancer.

scholarly journals S-Alkylated 1,2,4-Triazoles Derivatives Synthesis, spectral analysis and cytotoxicity evaluation

2019 ◽  
Vol 70 (1) ◽  
pp. 13-17
Author(s):  
Stefania-Felicia Barbuceanu ◽  
Octavian Tudorel Olaru ◽  
Laura-Ileana Socea ◽  
Constantin Draghici ◽  
Gabriel Saramet ◽  
...  
Keyword(s):  
Spectral Analysis ◽  
Daphnia Magna ◽  
1H Nmr ◽  
13C Nmr ◽  
Nmr Spectra ◽  
Ethyl Bromide ◽  
Phenacyl Bromide ◽  
13C Nmr Spectra ◽  
Ethyl Chloroacetate ◽  
Cytotoxicity Assessment

This paper presents synthesis, characterization and cytotoxicity assessment of six S-alkylated 1,2,4-triazoles derivatives that were obtained by treatment of some 1,2,4-triazole-3-thiones containing in the molecule phenylsulfonylphenyl and propyl or 4-bromophenylsulfonylphenyl and 4-methoxyphenyl fragments with different alkylation agents (ethyl bromide, ethyl chloroacetate or phenacyl bromide) in basic media. The synthesized compounds were physico-chemically characterized and the IR, 1H-NMR, 13C-NMR spectra were consistent with the assigned structures. The cytotoxicity of S-alkylated derivatives was evaluated on Daphnia magna crustacean.

scholarly journals New S-alkylated 1,2,4-triazoles incorporating diphenyl sulfone moieties with potential antibacterial activity

2009 ◽  
Vol 74 (10) ◽  
pp. 1041-1049 ◽  
Author(s):  
Stefania Barbuceanu ◽  
Gabriela Almajan ◽  
Ioana Saramet ◽  
Constantin Draghici ◽  
Radu Socoteanu ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Ethyl Bromide ◽  
Phenacyl Bromide ◽  
Antibacterial Effects ◽  
Ethyl Chloroacetate ◽  
Diphenyl Sulfone ◽  
New Compounds

Alkylation of the 5-{4-[(4-bromophenyl)sulfonyl]phenyl}-4-(3/4-methylphenyl)- 2,4-dihydro-3H-1,2,4-triazole-3-thiones 3a,b with various alkylation agents, i.e., ethyl bromide, phenacyl bromide and ethyl chloroacetate, afforded the S-substituted 1,2,4-triazoles 4-6a,b. The structures of these new compounds were elucidated by elemental analysis and IR, UV, 1H-NMR, 13C-NMR and MS spectroscopy. The newly synthesized products were tested for their antibacterial effects.

scholarly journals Nickel(II)-salen Schiff Base Complex as Anion Receptor

2014 ◽  
Vol 8 (3) ◽  
Author(s):  
Salasiah Endud ◽  
Wong Wen Yee
Keyword(s):  
Fourier Transform ◽  
Schiff Base ◽  
Infrared Spectroscopy ◽  
Fourier Transform Infrared Spectroscopy ◽  
Binding Affinity ◽  
1H Nmr ◽  
Diffuse Reflectance ◽  
Schiff Base Complex ◽  
Anion Receptor ◽  
Salen Complex

The Schiff base salen was incorporated to nickel(II) ion to afford nickel(II) diethylamino-substituted salen complex. The diethylamino-substituted salen l salen complex were characterized by Fourier Transform Infrared Spectroscopy (FTIR), diffuse reflectance ultravisible spectroscopy (DR UV-Vis) and 1H (1H-NMR). The binding affinity of the nickel(II) diethylamino-substituted salen complex towards specific anion in dichloromethane was investigated by us

Fused triazolotriazine bearing gem–dinitro group – a promising high energy density material

2021 ◽  
Author(s):  
Shaoqing Wang ◽  
Congcong Li ◽  
Tian Lu ◽  
Guilong Wang ◽  
Hongquan Yin ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Energy Density ◽  
1H Nmr ◽  
13C Nmr ◽  
High Energy ◽  
High Energy Density ◽  
Energetic Compounds ◽  
Fused Ring ◽  
Group A ◽  
High Energy Density Material

Six energetic compounds bearing the dinitromethyl group and based on the triazolotriazine fused ring skeleton were achieved. All structures were confirmed using infrared spectroscopy (IR), 1H NMR and 13C NMR...

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