scholarly journals Hepatoprotective effect of pomegranate (Punica granatum l.) in a rabbit model of steatohepatitis

2021 ◽  
Author(s):  
Durmuş Fatih BAŞER ◽  
Esra KÜPELİ AKKOL ◽  
Mehmet BOZKURT ◽  
İpek SÜNTAR ◽  
Turan CİVELEK
Keyword(s):  
Rabbit Model ◽  
Punica Granatum ◽  
Hepatoprotective Effect ◽  
Punica Granatum L

PHYTOCHEMICAL CONSTITUENTS, ANTIOXIDANT ACTIVITY AND ACUTE ORAL TOXICITY OF POMEGRANATE (PUNICA GRANATUM L.) FRUIT PEEL EXTRACT

2019 ◽  
pp. 7-14
Author(s):  
Hai Trieu Ly ◽  
Tuan Anh Vo ◽  
Viet Hong Phong Nguyen ◽  
Thi My Sa Pham ◽  
Bich Thao Lam ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Gallic Acid ◽  
Radical Scavenging ◽  
Dry Weight ◽  
Punica Granatum ◽  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
Fruit Peel ◽  
Total Polyphenol ◽  
Punica Granatum L

Background: The natural antioxidants have an important role in the prevention of many diseases. The aim of study is to investigate phytochemical components, antioxidant activity and acute oral toxicity of Pomegranate (Punica granatum L.) fruit peel (PFP) extract. Materials and methods: Phytochemicals of PFP were determined by qualitative chemical tests, thin layer chromatography, total polyphenol and flavonoid contents. The PFP extract was evaluated for antioxidant activity by DPPH assay and MDA assay. In vivo acute oral toxicity test was conducted using Karber-Behrens method to determine LD50. Results: Results illustrated that PFP mainly contains flavonoids, alkaloids, tannins, triterpenes, saponins, and coumarins. PFP extract exhibited the total polyphenol and flavonoid contents with 189.97 mg gallic acid equivalent/g dry weight and 9.42 mg quercetin equivalent/g dry weight, respectively. The DPPH free radical scavenging and anti-lipid peroxidation activities of PFP extract were expressed with IC50 value of 4.80 μg/mL and 0.38 μg/ mL, sequentially. Simultaneously, the Dmax (the maximum dose administered to mice that no toxicity was observed) of PFP extract was determined to be 21.28 g/kg, equivalent to 35.64 g dried herb. Conclusion: The PFP extract is relatively safe and revealed high antioxidant activity. Key words: Punica granatum L.; polyphenols; flavonoids; gallic acid; quercetin; antioxidant activity; acute oral toxicity

Anti-Stress Effect of Punica granatum L. Extract against Sleep Deprivation-Induced Impairment

2016 ◽  
Vol 45 (11) ◽  
pp. 1533-1543
Author(s):  
Ju-Ryun Na ◽  
Sunoh Kim ◽  
Ara Jo ◽  
Donghyuck Bae ◽  
Kyo-Nyeo Oh ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Punica Granatum ◽  
Stress Effect ◽  
Punica Granatum L

Identification of punicalagin as the bioactive compound behind the antimicrobial activity of pomegranate (Punica granatum L.) peels

2021 ◽  
Vol 352 ◽  
pp. 129396
Author(s):  
Clarisse Gosset-Erard ◽  
Minjie Zhao ◽  
Sonia Lordel-Madeleine ◽  
Saïd Ennahar
Keyword(s):  
Antimicrobial Activity ◽  
Bioactive Compound ◽  
Punica Granatum ◽  
Punica Granatum L

Enhancing pomegranate (Punica granatum L.) plant health through the intervention of a Streptomyces consortium

2020 ◽  
pp. 1-13
Author(s):  
P. Panneerselvam ◽  
G. Selvakumar ◽  
A. N. Ganeshamurthy ◽  
Debasis Mitra ◽  
Ansuman Senapati
Keyword(s):  
Punica Granatum ◽  
Plant Health ◽  
Punica Granatum L
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