scholarly journals Long-Term Angiographic Results of Recanalization of Small Diameter Coronary Arteries in Patients with Coronary Heart Disease

Author(s):  
E. V. Aksenov ◽  
R. B. Demchenko

One of the most serious problems of modern times are cardiovascular diseases, and these are the leading cause of death worldwide. The main contribution to the structure thereof belongs to coronary heart disease (CHD) which has become the greatest threat to the health of the population all over the world. The aim. To study the results of endovascular procedures in revascularization of small diameter coronary arteries. Materials and methods. The study included 417 patients aged 59 to 78 years with a mean diameter of the true in-ternal lumen of the arteries of 2.75±0.016 mm who underwent revascularization of the myocardium through stenting or percutaneous transluminal balloon coronary angioplasty (PTCA). In patients undergoing stenting of coronary artery (N=269), the mean diameter of the true internal lumen of the arteries was 2.68±0.03 mm. In the group of patients who underwent PTCA (N=148), this indicator was found to be 2.61±0.09 mm. The average degree of stenosis was 81.3±4.07%. The length of the artery stenosis was 12.4±0.71 mm. All the patients had the history of Q wave myocardial infarction (MI) more than 3 months ago, which made it possible to diagnose postinfarction cardiosclerosis. Ischemic history of more than 5 years was noted in 46 patients of this group (11.03% of cases), up to one year in 221 patients (70.2% of cases), from 1 to 2 years in 41 patients (9.83% cases), and 3 to 4 years in 38 people (9.11% of cases). Results and discussion. As a result of the studies, it was found that in patients with eccentric type of stenosis who used balloon angioplasty, restenosis in the remote postoperative period was 21% more frequent compared to a similar contingent of patients with implanted stents. In addition, restenosis of the stenosed area of the coronary artery > 1.5 mm in the distant period was 14.9% more common when PTCA was performed. And the frequency of remote restenosis (with complex morphology of initial damage of the arteries) in the stenting group was 14.2% lower than in the group of PTCA. Additionally, in the group of patients who underwent stenting, neoatherosclerosis in the treated segment was found in 92 patients (34.2 %). Patients with PTCA had a less progress of atherosclerosis (44 patients 29.72%) Conclusions. Restenosis in the remote postoperative period was 25.4 % less frequent in patients with eccentric ste-nosis who underwent stenting than in patients with balloon angioplasty. At the same time, restenosis of the stenosed area of CA >15 mm in the distant period was 10.43% more frequent during PTCA. In the coronary angioplasty group, patients with complicated morphology of basal damage of arteries had a 21.67% higher incidence of restenosis than in the coro-nary stenting group. Thus, we plan to carry out further study and analysis of immediate and long-term results of X-ray and endovascular operations in patients with coronary artery disease and small coronary artery diameter.

2019 ◽  
Vol 3 (12) ◽  
pp. 493-496
Author(s):  
Monitrya Nababan ◽  
Achmad Lefi ◽  
Djohar Nuswantoro

Objective: To determine the relationship of coronary heart disease traditional risk factors to the number of lesioned coronary arteries and calculate the relative risk. Methods: This study used an analytical research design with a retrospective cohort study design using patient catheterization report data. Data analysis was performed using the chi square test and relative risk in 449 individuals. Results: Based on the analysis results obtained p value 0.05 indicating no relationship between risk factors for coronary heart disease with the number of coronary arteries the lesions based on sex, history of hypertension and history of smoking. Conclusion: There is a relationship between age, history of diabetes mellitus, history of dyslipidemia and the number of coronary arteries that are lesions in patients with coronary heart disease and there is no relationship between sex, history of hypertension and smoking history with the number of coronary arteries that are lesions in patients with coronary heart disease. Keywords: single vessel disease; multivessel disease; coronary artery disease; risk factors CAD


2019 ◽  
Vol 90 (7) ◽  
pp. 792-795
Author(s):  
Shadi Yaghi ◽  
Andrew D Chang ◽  
Brittany A Ricci ◽  
Brian MacGrory ◽  
Shawna Cutting ◽  
...  

BackgroundThe aetiology of wall motion abnormalities (WMA) in patients with ischaemic stroke is unclear. We hypothesised that WMAs on transthoracic echocardiography (TTE) in the setting of ischaemic stroke mostly reflect pre-existing coronary heart disease rather than simply an isolated neurocardiogenic phenomenon.MethodsData were retrospectively abstracted from a prospective ischaemic stroke database over 18 months and included patients with ischaemic stroke who underwent a TTE. Coronary artery disease was defined as history of myocardial infarction (MI), coronary intervention or ECG evidence of prior MI. The presence (vs absence) of WMA was abstracted. Multivariable logistic regression was used to determine the association between coronary artery disease and WMA in models adjusting for potential confounders.ResultsWe identified 1044 patients who met inclusion criteria; 139 (13.3%, 95% CI 11.2% to 15.4%) had evidence of WMA of whom only 23 (16.6%, 95% CI 10.4% to 22.8%) had no history of heart disease or ECG evidence of prior MI. Among these 23 patients, 12 had a follow-up TTE after the stroke and WMA persisted in 92.7% (11/12) of patients. In fully adjusted models, factors associated with WMA were older age (OR per year increase 1.03, 95% 1.01 to 1.05, p=0.009), congestive heart failure (OR 4.44, 95% CI 2.39 to 8.33, p<0.001), history of coronary heart disease or ECG evidence prior MI (OR 27.03, 95% CI 14.93 to 50.0, p<0.001) and elevated serum troponin levels (OR 2.00, 95% CI 1.06 to 3.75, p=0.031).ConclusionIn patients with ischaemic stroke, WMA on TTE may reflect underlying cardiac disease and further cardiac evaluation may be considered.


2012 ◽  
Vol 11 (2) ◽  
pp. 39-43
Author(s):  
Z. Kh. Shugushev ◽  
Yu. V. Tarichko ◽  
Yu. A. Vasyuk

Aim. To analyze the results of different tactics of single-stent endovascular treatment among patients with coronary heart disease (CHD) and coronary artery bifurcation lesions (CABL). Material and methods. The study included 135 CHD patients with CABL. All participants were divided into 2 groups: Group I (n=77; 58,3 %) consisted of patients who underwent coronary artery (CA) main branch (MB) stenting and subsequent kissing balloon angioplasty of a CA side branch (SB). Group II (n=55) included patients with “genuine” CABL, who underwent only MB stenting with SB protection, but without SB balloon angioplasty. Results. In all 132 CABL patients, drug-eluting stents were successfully implanted, with technical effectiveness of 100 % and in-hospital survival of 100 %. Clinical outcomes were similar in both groups, with no major cardiovascular events registered. At the same time, such an important angiographic index as SB diameter was significantly higher in Group I, compared to Group II. At later stages, Group II patients required SB angioplasty and demonstrated habitual angina symptoms, ischemic electrocardiographic (ECG) changes, and slow SB blood flow (TIMI grade <III) after CA MB stenting. Conclusion. MB stenting of CA bifurcation without SB kissing balloon angioplasty cannot be recommended to all CABL patients. Development of habitual angina symptoms, ischemic ECG changes, and slow SB blood flow (TIMI grade <III) often requires subsequent SB kissing balloon angioplasty.


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