scholarly journals Relationship Between Risk Factors of Coronary Heart Disease on The Amount of Lesioned Coronary Artery

2019 ◽  
Vol 3 (12) ◽  
pp. 493-496
Author(s):  
Monitrya Nababan ◽  
Achmad Lefi ◽  
Djohar Nuswantoro

Objective: To determine the relationship of coronary heart disease traditional risk factors to the number of lesioned coronary arteries and calculate the relative risk. Methods: This study used an analytical research design with a retrospective cohort study design using patient catheterization report data. Data analysis was performed using the chi square test and relative risk in 449 individuals. Results: Based on the analysis results obtained p value 0.05 indicating no relationship between risk factors for coronary heart disease with the number of coronary arteries the lesions based on sex, history of hypertension and history of smoking. Conclusion: There is a relationship between age, history of diabetes mellitus, history of dyslipidemia and the number of coronary arteries that are lesions in patients with coronary heart disease and there is no relationship between sex, history of hypertension and smoking history with the number of coronary arteries that are lesions in patients with coronary heart disease. Keywords: single vessel disease; multivessel disease; coronary artery disease; risk factors CAD

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Desire Sutrisno ◽  
Agnes L. Panda ◽  
Jeffrey Ongkowijaya

Abstract: Coronary Heart Disease is a heart disease caused by the narrowing of the coronary arteries, which then disturbs the flow of blood to the myocardium. The result of SKRT done by the Health Department Republic of Indonesia showed that deaths due to CHD kept increasing throughout the years, and this had made CHD as the first most common cause of death. This study aimed to find out about the overview of lipid profile in coronary heart disease patients who had consumed statin and who had not. This was a descriptive method, based on the secondary data that were attained directly from patients in CVBC and Irina F Cardiology Department Prof. Dr. R.D. Kandou Hospital. The population in this study were patients with coronary heart disease recorded in medical records inn December 2014 and met the inclusion criteria. The results showed that male CHD patients who consumed statin were 64.7% and non-statin 75.0%; the 36-45 age group and >55 were most commonly found in statins group (35.3%), and age of 36-45 (33.3%) in non-statin group. Smoking history in statin group and non-statin were 52.9% and 62.5%; history of hypertension in statin group and non-statin were 76.5% and 62.5%; history of diabetes mellitus in statin group and non-statin group are 11.8% and 33.3%; familial history of heart disease in statin group and non-statin group were 70.6% and 54.2%; the increase total cholesterol in statin group and non-statin group were 52.9% and 54.2%; the increase of triglycerides in statin group and non-statin groups were 0% and 8,3%; the increase in LDL cholesterol in statin group and non-statin group were 29.4% and 25.0%; the decrease of HDL in statin group and non-statin group were 0% and 25.0%; suffered dyslipidemia in statin group and non-statin are 52.9% and 62.5%, high non-HDL level in statin group and non-statin group were 52.9% and 58.3%; history of uric acid in statin group and non-statin group were 64.7% and 62.5%; type of CHD most commonly found in statin group ATS wre 70.6% and non-statin group NSTEMI 45.8%. Based on the results of this study, the CHD risk factors such as smoking, hypertension, family history of heart disease, dyslipidemia, non-HDL levels, uric acid affected the incidence of CHD more than the diabetes mellitus risk factor.Keywords: coronary heart disease, risk factors, lipid profileAbstrak:Penyakit jantung koroner adalah penyakit jantung yang disebabkan oleh adanya penyempitan pada arteri koronaria, sehingga aliran darah ke otot jantung menjadi terganggu. Hasil survei kesehatan rumah tangga (SKRT) departemen kesehatan Republik Indonesia menunjukkan bahwa dari tahun ke tahun kematian yang disebabkan Penyakit Jantung Koroner makin meningkat dan saat ini menduduki urutan pertama. Penelitian ini bertujuan untuk mengetahui gambaran profil lipid pada pasien penyakit jantung koroner yang telah menggunakan obat statin dan belum menggunakan obat statin. Metode yang digunakan bersifat deskriptif berdasarkan data sekunder yang didapatkan secara langsung pada pasien yang berada di CVBC dan irina F Jantung RSUP Prof. Dr. R.D.Kandou. Populasi pada penelitian ini yaitu penderita Penyakit Jantung Koroner yang tercatat di rekam medik pada 420Sutrisno, Panda, Ongkowijaya: Gambaran profil lipid...bulan Desember 2014 dan memenuhi kriteria inklusi. Penelitian ini menunjukan bahwa pasien PJK berjenis kelamin laki-laki pengguna statin sebesar 64,7% dan non-statin 75,0%. Pada kelompok statin terbanyak umur 36-45 dan 56 ke-atas serta non-statin pada umur 36-45. Riwayat merokok pada pengguna statin dan non-statin sebesar 52,9% dan 62,5%. Riwayat hipertensi pada pengguna statin dan non-statin sebesar 76,5% dan 62,5%. Pasien PJK yang memiliki riwayat diabetes mellitus pada pengguna statin dan non-statin sebesar 11,8% dan 33,3%, yang memiliki riwayat penyakit jantung dalam keluarga pada pengguna statin dan non statin sebesar 70,6% dan 54,2%, peningkatan kolesterol total pada pengguna statin dan non-statin sebesar 52,9% dan 54,2%, peningkatan trigliserida pada pengguna statin dan non-statin sebesar 0% dan 8,3%, peningkatan kolesterol LDL pada pengguna statin dan non-statin sebesar 29,4% dan 25,0%, penurunan HDL pada pengguna statin dan non-statin sebesar 0% dan 25,0%, yang menderita dislipidemia pada pengguna statin dan non-statin sebesar52,9% dan 62,5%, kadar non-HDL yang tinggi pada pengguna statin dan non-statin sebesar 52,9% dan 58,3%, riwayat asam urat pada pengguna statin dan non-statin sebesar 64,7% dan 62,5%. Jenis PJK terbanyak pada pengguna statin ATS sebesar 70,6% dan non-statin NSTEMI sebesar 45,8%. Kesimpulan dalam penelitian ini yaitu faktor resiko seperti merokok, hipertensi, riwayat penyakit jantung dalam keluarga, dislipidemia, kadar non-HDL, asam urat lebih mempengaruhi terjadinya PJK dibandingkan dengan faktor resiko diabetes melitus.Kata kunci: penyakit jantung koroner, faktor risiko, profil lipid


2020 ◽  
Vol 1 (1) ◽  
pp. 21-30
Author(s):  
Deviana Widayanti ◽  
Chatarina Setya Widyastuti

Background: Coronary Heart Disease (CHD) Is a condition when the arteries that supply blood to the heart wall experience hardening and narrowing. It is estimated that 30% of coronary heart disease causes death worldwide. Objective: This study aims to determine the risk factors for CHD in Panti Rapih Hospital. Methods: This descriptive study aims to determine the risk factors for CHD in outpatients at Panti Rapih Hospital. The population is patients who have been diagnosed with coronary heart disease and the sample was taken by 50 respondents with non-random accidental sampling technique. This research take the data use questionnaire and make univariat analysis. Results: Risk factors for CHD are a number of factors that cannot be changed: family history of 42%, age = 40 years 95% in men and 95% age = 65 years in women. Factors that can be changed are: Smoking 78%, history of hypertension 68%, history of diabetes mellitus 28%, dyslipidemic 90%, excess body weight42% and lack of exercise 38%. Conclusion: Risk factors for CHD that cannot be changed: family history of 42%, age = 40 years 95% in men and 95% age = 65 years in women. Factors that can be changed are: Smoking 78%, history of hypertension 68%, history of diabetes mellitus 28%, dyslipidemic 90%, excess body weight 42% and lack of exercise 38%.     Keywords: coronary heart disease, risk factors


Author(s):  
E. V. Aksenov ◽  
R. B. Demchenko

One of the most serious problems of modern times are cardiovascular diseases, and these are the leading cause of death worldwide. The main contribution to the structure thereof belongs to coronary heart disease (CHD) which has become the greatest threat to the health of the population all over the world. The aim. To study the results of endovascular procedures in revascularization of small diameter coronary arteries. Materials and methods. The study included 417 patients aged 59 to 78 years with a mean diameter of the true in-ternal lumen of the arteries of 2.75±0.016 mm who underwent revascularization of the myocardium through stenting or percutaneous transluminal balloon coronary angioplasty (PTCA). In patients undergoing stenting of coronary artery (N=269), the mean diameter of the true internal lumen of the arteries was 2.68±0.03 mm. In the group of patients who underwent PTCA (N=148), this indicator was found to be 2.61±0.09 mm. The average degree of stenosis was 81.3±4.07%. The length of the artery stenosis was 12.4±0.71 mm. All the patients had the history of Q wave myocardial infarction (MI) more than 3 months ago, which made it possible to diagnose postinfarction cardiosclerosis. Ischemic history of more than 5 years was noted in 46 patients of this group (11.03% of cases), up to one year in 221 patients (70.2% of cases), from 1 to 2 years in 41 patients (9.83% cases), and 3 to 4 years in 38 people (9.11% of cases). Results and discussion. As a result of the studies, it was found that in patients with eccentric type of stenosis who used balloon angioplasty, restenosis in the remote postoperative period was 21% more frequent compared to a similar contingent of patients with implanted stents. In addition, restenosis of the stenosed area of the coronary artery > 1.5 mm in the distant period was 14.9% more common when PTCA was performed. And the frequency of remote restenosis (with complex morphology of initial damage of the arteries) in the stenting group was 14.2% lower than in the group of PTCA. Additionally, in the group of patients who underwent stenting, neoatherosclerosis in the treated segment was found in 92 patients (34.2 %). Patients with PTCA had a less progress of atherosclerosis (44 patients 29.72%) Conclusions. Restenosis in the remote postoperative period was 25.4 % less frequent in patients with eccentric ste-nosis who underwent stenting than in patients with balloon angioplasty. At the same time, restenosis of the stenosed area of CA >15 mm in the distant period was 10.43% more frequent during PTCA. In the coronary angioplasty group, patients with complicated morphology of basal damage of arteries had a 21.67% higher incidence of restenosis than in the coro-nary stenting group. Thus, we plan to carry out further study and analysis of immediate and long-term results of X-ray and endovascular operations in patients with coronary artery disease and small coronary artery diameter.


2018 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
David Rubiyaktho ◽  
Cholid Tri Tjahjono

Background: According to Framingham Study, independent risk factors for coronary heart disease (CHD) are diabetes, hypertension, smoking, dyslipidemia, family history of CHD and obesity. Previous study reported cut-off value of Duke Treadmill Score (DTS) < -0.5 represents a significant coronary lesion with positive predictive value 88.4%. Objective: To compare the incidence of predicted significant coronary lesions by DTS among various risk factors for coronary heart disease. Methods: A cross sectional study was done on 292 patients age 18 to 74 years old who had positive exercise testing for CAD screening during period of June 1st 2016 until May 30th 2017. DTS was calculated from treadmill test as: exercise time - (5 x ST deviation in mm) - (4 x exercise angina). A coronary lesion was predicted significant with DTS cut off value < -0.5. Results: Subjects mean age was 57 years old, male were 60.4%. The risk factors for CHD were found sequentially from the most frequent were hypertension 51.9%, smoking 35.3%, diabetes mellitus 23.1%, dyslipidemia 11.9%, obesity 4.2% and family history of CHD 6.3%. It was found that diabetes was significantly different from its effect on DTS value with p value = 0.021, while hypertension, obesity, dyslipidemia and family history CHD had no significant effect. Logistic regression found consistently that diabetes was significant (p=0.019). Conclusion: Predicted significant coronary lesions by DTS developed more frequent in diabetes compared to, hypertension, smoking, dyslipidemia, obesity and family history of coronary heart disease.


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