scholarly journals The Level Of Knowledge on the Use Of NSAIDs As Analgesic For Dysmenorrhea Case In Faculty of Health Universitas Muhammadiyah Lamongan

2020 ◽  
Vol 12 (2) ◽  
pp. 287
Author(s):  
Primanitha Ria Utami ◽  
Devi Ristian Octavia ◽  
Selly Septi Fandinata

Non-steroidal anti-inflammatory (anti-inflammatory) drugs, or better known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) or NSAIDs are a group that has analgesic (pain reliever), anti-pyretic (fever) properties. to determine the level of knowledge on the use of NSAIDs as anti-pain in cases of dysmenorrhea in the University of Muhammadiyah Lamongan. The research design used in this research is descriptive, in taking the sample using the total sampling technique. Collecting data by distributing questionnaires with data analysis presented in tabular form. The results of this study indicate that of the 266 respondents, almost all respondents know about knowledge of dysmenorrhea well (83.8%). In the results of this study, there were still respondents who did not know the proper use of NSAIDs as analgesic. So in this case the role of pharmaceutical personnel is needed in providing information or education to people who consume NSAIDs, in order to achieve a quality of life for the community and avoid unwanted therapeutic responses. Keywords : NSAID ; dysmenorrhea ; analgesic 

2021 ◽  
Vol 7 (1) ◽  
pp. 27-35
Author(s):  
Ghulam Shabir ◽  
Arif Ahmad ◽  
Imran Shah ◽  
Rana Faizan Ali

Background: Regular feelings of anxiety is a severe life and highly prevalent psychiatric disorder which becomes one of the major cause of death across the globe. Although the exact causes responsible for anxiety are not known only in Pakistan 44 % of the population is facing anxiety problems which leads to many other diseases and low quality of life. Objectives: To investigate whether the youth of Pakistan is facing anxiety problems, what are the major cause of anxiety, how anxiety can be managed, and to study the role of prayers in anxiety management.  Method: The researcher select 400 respondents from two universities of Lahore (the University of Central Punjab and Punjab University) through a systematic random sampling technique. In the first phase, the researcher filters those people who did not face an anxiety problem in the last month. Researchers collect data only from those respondents who can recall and face an anxiety problem in the last month. Results: Rate of anxiety among the youth of Pakistan is alarming, as (71 %) of the respondent said that they face anxiety problems. But there is a very significant relationship between prayers and anxiety management. Conclusion: The researcher concludes that prayers can be used to manage or reduce anxiety.


2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Ricardo da Cruz Lage ◽  
Claudia Diniz Lopes Marques ◽  
Thauana Luiza Oliveira ◽  
Gustavo Gomes Resende ◽  
Charles Lubianca Kohem ◽  
...  

AbstractSpondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis (axSpA). However, the emergence of the immunobiologic agents brought up the discussion about the role of NSAIDs in the management of these patients. The objective of this guideline is to provide recommendations for the use of NSAIDs for the treatment of axSpA. A panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis of randomized clinical trials for 15 predefined questions. The Grading of Recommendations, Assessment, Development and Evaluation methodology to assess the quality of evidence and formulate recommendations were used, and at least 70% agreement of the voting panel was needed. Fourteen recommendations for the use of NSAIDs in the treatment of patients with axSpA were elaborated. The purpose of these recommendations is to support clinicians’ decision making, without taking out his/her autonomy when prescribing for an individual patient.


2020 ◽  
pp. 137-149
Author(s):  
Krzysztof Szewior

The author focuses on the manner and effects of German higher education reforms that have changed the model of university management. The point of reference is the quality of education and its role, how universities ensure it, and how it is verified through evaluation and accreditation. These elements divide the article into two parts: a part about quality and a part about evaluation and accreditation. The analysis includes the impact of global processes and Europeanization. The research approach is characteristic for public policies, sciences of management and quality. The theories used in this article: the theory of systems and neo-institutionalism, as well as perspectives: the university as an active strategic partner, entrepreneurial university, the third role of universities. The publication is based on desk research and on the analysis of processes.


2021 ◽  
Vol 14 (7) ◽  
pp. 692
Author(s):  
Ryldene Marques Duarte da Cruz ◽  
Francisco Jaime Bezerra Mendonça-Junior ◽  
Natália Barbosa de Mélo ◽  
Luciana Scotti ◽  
Rodrigo Santos Aquino de Araújo ◽  
...  

Rheumatoid arthritis, arthrosis and gout, among other chronic inflammatory diseases are public health problems and represent major therapeutic challenges. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most prescribed clinical treatments, despite their severe side effects and their exclusive action in improving symptoms, without effectively promoting the cure. However, recent advances in the fields of pharmacology, medicinal chemistry, and chemoinformatics have provided valuable information and opportunities for development of new anti-inflammatory drug candidates. For drug design and discovery, thiophene derivatives are privileged structures. Thiophene-based compounds, like the commercial drugs Tinoridine and Tiaprofenic acid, are known for their anti-inflammatory properties. The present review provides an update on the role of thiophene-based derivatives in inflammation. Studies on mechanisms of action, interactions with receptors (especially against cyclooxygenase (COX) and lipoxygenase (LOX)), and structure-activity relationships are also presented and discussed. The results demonstrate the importance of thiophene-based compounds as privileged structures for the design and discovery of novel anti-inflammatory agents. The studies reveal important structural characteristics. The presence of carboxylic acids, esters, amines, and amides, as well as methyl and methoxy groups, has been frequently described, and highlights the importance of these groups for anti-inflammatory activity and biological target recognition, especially for inhibition of COX and LOX enzymes.


BMJ ◽  
1992 ◽  
Vol 305 (6858) ◽  
pp. 865-868 ◽  
Author(s):  
L. A. Garcia Rodriguez ◽  
S. Perez Gutthann ◽  
A. M. Walker ◽  
L. Lueck

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