Optical density of bone tissue in the dynamics of therapy of professionally caused osteopathies of the shoulder joint

Author(s):  
V. N. Druzhinin ◽  
V. G. Suvorov ◽  
A. E. Shelekhova

Optical density index can be a criterion of bone mineral saturation, both at the stage of primary diagnosis and in the dynamics of observation of patients with shoulder periarthrosis and osteoarthritis of the shoulder joint.

2020 ◽  
Vol 224 ◽  
pp. 04012
Author(s):  
A V Litvinovich ◽  
O Yu Pavlova ◽  
A V Lavrishchev ◽  
A. A. Belimov

The composition of organo-mineral complexes (OMC) migrating from the arable horizon limed by Umbric Albeluvisol Abruptic was studied. The carbon content in organic-mineral complexes (OMC) ranged from 5.5 to 5.7%. The optical density index (Esmg/ml) varied in the range of values from 2.7 to 3.1, characteristic for fulvic acids (FA). It was established that FAs averaged with bases retain the ability to exert a destructive effect on soil minerals, transferring a significant amount of Al, Mn, and Fe into solution. According to their ability to migrate as part of OMC, the elements studied in the experiment with dolomite particles at a dose of 7.35 t/ha were arranged in the following decreasing sequence: Mn > Al > Fe. In the experiment with conversion chalk (CC) at a dose of 20.25 t/ha, this sequence was Al > Mn > Fe.


2015 ◽  
Vol 54 (3) ◽  
pp. 795-797 ◽  
Author(s):  
Isabel Spriet ◽  
Katrien Lagrou ◽  
Johan Maertens ◽  
Ludo Willems ◽  
Alexander Wilmer ◽  
...  

False-positive galactomannan (GM) results have been reported in patients treated with gluconate-containing solutions, such as Plasmalyte. The GM optical density index was tested on 33 distinct batches of Plasmalyte and was found to be negative in all of the batches, confirming that Plasmalyte is no longer a cause of false-positive GM results.


Author(s):  
S. T. Havryltsiv

There is a signifi cant scientifi c and practical interest in the study of bone mineral density in the jaw destructive processes caused by tumors in patients without bone remodeling disorders on the background of osteoporosis.The aim of the study – to conduct a comparative evaluation of jaw bone optical density in areas adjacent to radicular cysts depending on the osteoregenerating status of patients.Materials and Methods. 45 patients (20 males and 25 females) aged 20 to 70 years with radicular jaw cysts who were on an outpatient treatment at the Surgical Department of the Medical Stomatological Center of Danylo Halytskyi Lviv National Medical University were examined. Determination of bone mineral density (BMD) in patients was conducted by ultrasound bone densitometer Achilles (LUNAR Corp. (USA)) by measuring the time of ultrasonic waves pass through the calcaneus. Bone mineral density in patients was analyzed for the Z criterion. All patients underwent standard orthopantomograms on an X-ray apparatus Orthophos XG (Sirona). For the qualitative characteristics of mandibular cortical layer we used MCI index (mandibular cortical index) by Klemetti E. et al. (1994). According to published data, the index serves as an indicator of MCI systematic reduction of mineral density of the facial skeleton. Digital orthopantomograms analyzed by using the ImageJ software, which allows measuring the optical density of bone tissue at any selected jawbone area in standard brightness units in grayscale from 0 to 256 (the minimum values correspond to the background of the radiographs). The optical density of bone tissue was determined in a region directly adjacent to the shell of the radicular cyst, and compared with the intact bone on the symmetrical side of the jaw. Statistical analysis of the research results was carried out by a computer program of statistical calculation Statistica 8.Results and Discussion. As a result of ultrasound densitometry of the calcaneus in 17 women aged 45 to 60 years, we found signs of osteopenia and osteoporosis. Indicators of BMD within the age norm were detectedin 6 surveyed women who were younger than 45 years. Among the surveyed men of all ages signs of age norms were found much more frequently – in 11 cases. The MCI mandible index is in 87 % of cases directly correlated with state of bone mineral density determined by ultrasound densitometry, which is being consisted with literature data. In the absence of systemic disorders of mineral metabolism, the parameters of optical density in areas adjacent to the shells of the radicular cysts were higher compared to intact bones (p <0.05), which, in our opinion, testifi es about the compensatory reaction of the bone tissue that is subjected to pathological infl uence (compression) from the side of the cyst shell. On the background of systemic osteoporosis, optic density of jaw bones in the area of injury compared to intact sides is decreased.Conclusions. Determination of the optical density of the jaw bones adjacent to the radicular cysts can be used as a screening test for the study of osteo-regenerative potential in patients and should be taken into account when choosing surgical treatment methods.


2017 ◽  
Vol 61 (3) ◽  
pp. 357-362 ◽  
Author(s):  
Ewa Tomaszewska ◽  
Piotr Dobrowolski ◽  
Siemowit Muszyński ◽  
Krzysztof Kostro ◽  
Iwona Taszkun ◽  
...  

AbstractIntroduction: The aim of the study was to investigate the mechanical and geometric properties as well as bone tissue and mineral density of long bones in mink dams exposed to deoxynivalenol (DON) since one day after mating, throughout gestation (ca. 46 d) and lactation to pelt harvesting. Material and Methods: Thirty clinically healthy multiparous minks (Neovison vison) of the standard dark brown type were used. After the mating, the minks were randomly assigned into two equal groups: nontreated control group and DON group fed wheat contaminated naturally with DON at a concentration of 1.1 mg·kg-1of feed. Results: The final body weight and weight and length of the femur did not differ between the groups. However, DON contamination decreased mechanical endurance of the femur. Furthermore, DON reduced the mean relative wall thickness and vertical wall thickness of the femur, while vertical cortical index, midshaft volume, and cross-sectional moment of inertia increased. Finally, DON contamination did not alter bone tissue density, bone mineral density, or bone mineral content, but decreased the values of all investigated structural and material properties. Conclusion: DON at applied concentration probably intensified the process of endosteal resorption, which was the main reason for bone wall thinning and the weakening of the whole bone.


2018 ◽  
Vol 63 (2) ◽  
pp. 41-46 ◽  
Author(s):  
А. Рыжков ◽  
A. Ryzhkov ◽  
А. Крылов ◽  
A. Krylov ◽  
А. Блудов ◽  
...  

Purpose: To determine the diagnostic capabilities of body scan (BS) and SPECT/CT in the diagnosis of various variants of bone metastases (BM). Material and methods: The data of 37 patients with BM of breast cancer (20 patients), prostate cancer (7 patients) and other tumors various localization (10 patients) were analyzed. The study was carried out in two stages: first, BS was performed, 3 hours after intravenous introduction of an osteotropic radiopharmaceutical labeled with 99mTc (technephor or phosphotech), followed by SPECT/CT of the selected zone of interest. All studies were performed on a combined system Symbia T2 (Siemens) with a 2-slice low dose CT. Results: With BS the foci of the tumor lesion were identified in 33 cases, and in SPECT/CT in 37 cases. There were detected 159 BM (21 sites: 0.4–0.9, 59 sites: 1.0–1.9, 79 sited: 2.0–4.5 cm). The total detectable incidence of metastases with BS was 66.0 % (105 BM) of all metastases detected in comparison with SPECT/CT (159 BM). Detectability with BS increased with increasing size of detectable foci. Foci less than 1 cm are detected in isolated case (1 from 21 cases). Metastases measuring from 1 cm to 1.9 cm are detected only in 52.5 % of cases (31 from 59 cases). The detectability of large metastases (2 cm or more) with BS (92.4 %) approaches the SPECT/CT (100 %) – 73 from 79 cases. There were detected with BS 27 osteoblastic BM in comparison 56 BM with SPECT/CT (48.2 %). The detectability with BS of mixed BM (76.3 %) and octeolitic BM (75.4 %) showed no differences. Firstly it can be explained by a predominance of smaller osteoblastic foci, and secondly reparative processes in metastases, accompanied by reduction of the radiopharmaceutical. The correction of the conclusion of the BS was required just in 24 cases: in 8 cases, when the BS was marked overdiagnosis, 16 – underdiagnosis. However, BS does not lose its value as a screening. In one case, even if BS has been revealed metastasis, it is not yet accompanied by destruction of bone tissue. Despite such significant differences in diagnostic accuracy of BS and SPECT/CT, BS proved to be uninformative only in 2 cases: when undetected metastases without primary tumor identified, and in the case of the screening of metastasis the accumulation of the radiopharmaceutical in the bladder. In 2 other cases, the lack of accumulation of the radiopharmaceutical was determined by the reparation that can only be considered conditionally uninformative. However, SPECT/CT shows clear advantages in the visualization of bone metastases due to computed tomography, allowing to estimate the structure of bone tissue. In 9 cases even to SPECT-slices metastases were not accompanied by pathological accumulation of the radiopharmaceutical. Conclusion: SPECT/CT is a highly informative method for detecting bone metastases, the use of which allows reducing the time of examination and dose irradiation of patients due to the rejection of additional radiological procedures. In addition, SPECT/CT at the same time allows differential diagnosis of structural and metabolic bone changes, which increases both the accuracy of primary diagnosis and control of treatment.


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