The prediction of CSF gusher in cochlear implants with inner ear abnormality

2012 ◽  
Vol 132 (12) ◽  
pp. 1271-1274 ◽  
Author(s):  
Liu Hongjian ◽  
Wang Guangke ◽  
Ma Song ◽  
Ding Xiaoli ◽  
Zhang Daoxing
Keyword(s):  
Inner Ear ◽  
Cochlear Implants

Cochlear implants for congenital deformities

1992 ◽  
Vol 106 (11) ◽  
pp. 967-970 ◽  
Author(s):  
P. D. Phelps
Keyword(s):  
High Resolution ◽  
Inner Ear ◽  
Cochlear Implants ◽  
Thin Section ◽  
High Resolution Ct ◽  
Congenital Deformities ◽  
Vestibular Aqueduct ◽  
Ct Studies

AbstractThere have been few accounts of multi-channel cochlear implants in patients with congenital structural deformities of the inner ear which are associated with severe and sometimes progressive deafness. These malformations can now be recognized easily on 2 plane thin section high resolution CT studies which are mandatory for the pre-implantation assessment. However, no attempt seems to have been made to describe which of these malformations would be suitable for an implant or for which would this procedure be contra-indicated. True Mondini deformity of both the cochlea and dilated vestibular aqueduct type would appear suitable for a multi channel implant, but this type of implant should not be used for a primitive otocyst, severe labyrinthine dysplasia or the characteristic X-linked deformity.

Review paper: Cochlear Implants and Inner Ear Based Therapy

2009 ◽  
Vol 2 (2) ◽  
Author(s):  
Ciorba A. ◽  
Astolfi L. ◽  
Jolly C. ◽  
Martini A.
Keyword(s):  
Inner Ear ◽  
Cochlear Implants ◽  
Review Paper

scholarly journals Cochlear Implant Outcomes and Genetic Mutations in Children with Ear and Brain Anomalies

2015 ◽  
Vol 2015 ◽  
pp. 1-19 ◽  
Author(s):  
Micol Busi ◽  
Monica Rosignoli ◽  
Alessandro Castiglione ◽  
Federica Minazzi ◽  
Patrizia Trevisi ◽  
...  
Keyword(s):  
Cochlear Implant ◽  
Inner Ear ◽  
Cochlear Implants ◽  
Cochlear Implantation ◽  
Developmental Disorders ◽  
Statistical Tests ◽  
Study Group ◽  
Brain Abnormalities ◽  
Brain Anomalies ◽  
Ear Malformations

Background. Specific clinical conditions could compromise cochlear implantation outcomes and drastically reduce the chance of an acceptable development of perceptual and linguistic capabilities. These conditions should certainly include the presence of inner ear malformations or brain abnormalities. The aims of this work were to study the diagnostic value of high resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) in children with sensorineural hearing loss who were candidates for cochlear implants and to analyse the anatomic abnormalities of the ear and brain in patients who underwent cochlear implantation. We also analysed the effects of ear malformations and brain anomalies on the CI outcomes, speculating on their potential role in the management of language developmental disorders.Methods. The present study is a retrospective observational review of cochlear implant outcomes among hearing-impaired children who presented ear and/or brain anomalies at neuroimaging investigations with MRI and HRCT. Furthermore, genetic results from molecular genetic investigations (GJB2/GJB6and, additionally, in selected cases,SLC26A4or mitochondrial-DNA mutations) on this study group were herein described. Longitudinal and cross-sectional analysis was conducted using statistical tests.Results. Between January 1, 1996 and April 1, 2012, at the ENT-Audiology Department of the University Hospital of Ferrara, 620 cochlear implantations were performed. There were 426 implanted children at the time of the present study (who were <18 years). Among these, 143 patients (64 females and 79 males) presented ear and/or brain anomalies/lesions/malformations at neuroimaging investigations with MRI and HRCT. The age of the main study group (143 implanted children) ranged from 9 months and 16 years (average = 4.4; median = 3.0).Conclusions. Good outcomes with cochlear implants are possible in patients who present with inner ear or brain abnormalities, even if central nervous system anomalies represent a negative prognostic factor that is made worse by the concomitant presence of cochlear malformations. Common cavity and stenosis of the internal auditory canal (less than 2 mm) are negative prognostic factors even if brain lesions are absent.

B097 Results in treatment of inner ear malformations with cochlear implants and brainstem implants

2011 ◽  
Vol 75 ◽  
pp. 27-28
Author(s):  
M. Manrique ◽  
J. De Abajo ◽  
R. Manrique ◽  
A. Huarte ◽  
C. Morera ◽  
...  
Keyword(s):  
Inner Ear ◽  
Cochlear Implants ◽  
Inner Ear Malformations ◽  
Ear Malformations

scholarly journals Severe and persistent facial nerve stimulation after cochlear implantation in a patient with cochlear–facial dehiscence: a case report

2021 ◽  
Vol 49 (11) ◽  
pp. 030006052110578
Author(s):  
Jingyuan Chen ◽  
Biao Chen ◽  
Lifang Zhang ◽  
Yongxin Li
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Facial Nerve ◽  
Inner Ear ◽  
Cochlear Implants ◽  
Nerve Stimulation ◽  
Cochlear Implantation ◽  
Computed Tomography Images ◽  
Ear Malformations ◽  
Facial Nerve Stimulation

Generally, cochlear implants (CIs) are effective in helping patients improve their hearing performance; however, some patients have poor hearing performance owing to facial nerve stimulation (FNS), which is often associated with cochlear anomalies. We report a case with a normal cochlea and severe and persistent FNS owing to cochlear–facial dehiscence (CFD) that affected the CI outcomes. Preoperatively, a careful review of the computed tomography images before CI surgery is necessary not only for patients with otosclerosis and inner ear malformations but also for patients with normal cochlear structures because facial nerve anomalies could be present.

Review paper Cochlear Implants and Inner Ear Based Therapy

nano Online ◽  
2016 ◽  
Author(s):  
A. Ciorba ◽  
L. Astolfi ◽  
C. Jolly ◽  
A. Martini ◽  
Alessandro Martini
Keyword(s):  
Inner Ear ◽  
Cochlear Implants ◽  
Review Paper

scholarly journals Toward steerable electrodes. An overview of concepts and current research.

2017 ◽  
Vol 3 (2) ◽  
pp. 765-769 ◽  
Author(s):  
Thomas S. Rau ◽  
Silke Hügl ◽  
Thomas Lenarz ◽  
Omid Majdani
Keyword(s):  
Inner Ear ◽  
Cochlear Implants ◽  
Basilar Membrane ◽  
Clinical Success ◽  
Electrode Array ◽  
Surrounding Tissue ◽  
Clinical Implementation ◽  
The Past ◽  
The Individual ◽  
Insertion Process

AbstractRestoration of hearing is a demanding surgical task which requires the insertion of a cochlear implant electrode array into the inner ear while preserving the delicate basilar membrane inside the cochlea for an atraumatic insertion. Already shortly after the first clinical success with early versions of cochlear implants the desire for a controlled insertion of the electrode array arose. Such a steerable electrode should be in its shape adaptable to the individual path of the helical inner ear in order to avoid any contact between the implant and the surrounding tissue. This article provides a short overview of concepts and actuator mechanisms investigated in the past and present with the objective of developing a steerable electrode array for an individualized insertion process. Although none of these concepts has reached clinical implementation, there are promising experimental results indicating that insertion forces can be reduced up to 60% compared to straight and not steerable electrodes. Finally, related research topics are listed which require considerable further improvements until steerable electrodes will reach clinical applicability.

scholarly journals Characteristics and clinical use of ocular and cervical vestibular evoked myogenic potentials for evaluating paediatric candidates for cochlear implants

2016 ◽  
Vol 131 (1) ◽  
pp. 56-63 ◽  
Author(s):  
X-D Xu ◽  
J Hu ◽  
Q Zhang ◽  
Y Zhang ◽  
X-T Zhang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cochlear Implant ◽  
Inner Ear ◽  
Temporal Bone ◽  
Cochlear Implants ◽  
Bone Structure ◽  
Vestibular Evoked Myogenic Potentials ◽  
Vestibular Evoked Myogenic Potential ◽  
Myogenic Potential ◽  
Ear Malformations

AbstractObjective:This study aimed to define the characteristics and use of ocular and cervical vestibular evoked myogenic potentials for evaluating paediatric cochlear implant candidates.Methods:Ocular and cervical vestibular evoked myogenic potentials of 34 paediatric cochlear implant candidates were analysed. All patients also underwent a routine audiological examination, including computed tomography.Results:In all, 27 patients with normal inner-ear structures had absent or impaired vestibular evoked myogenic potential responses. In paediatric candidates with inner-ear malformations, ocular and cervical vestibular evoked myogenic potentials had lower thresholds and higher amplitudes. Vestibular evoked myogenic potential responses in this cohort were classified into three groups. There was significant concordance between vestibular evoked myogenic potentials and temporal bone computed tomography findings.Conclusion:Ocular and cervical vestibular evoked myogenic potential waveforms were different in paediatric candidates with normal and abnormal inner-ear structures. Therefore, vestibular evoked myogenic potential responses can indicate temporal bone structure.

scholarly journals Microimaging of a novel intracochlear drug delivery device in combination with cochlear implants in the human inner ear

2021 ◽  
Author(s):  
Eric Lehner ◽  
Matthias Menzel ◽  
Daniel Gündel ◽  
Stefan K. Plontke ◽  
Karsten Mäder ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Inner Ear ◽  
Cochlear Implants ◽  
Drug Carrier ◽  
Drug Application ◽  
Scala Tympani ◽  
Carrier System ◽  
Temporal Bones ◽  
Drug Carrier System ◽  
Human Inner Ear

AbstractThe effective delivery of drugs to the inner ear is still an unmet medical need. Local controlled drug delivery to this sensory organ is challenging due to its location in the petrous bone, small volume, tight barriers, and high vulnerability. Local intracochlear delivery of drugs would overcome the limitations of intratympanic (extracochlear) and systemic drug application. The requirements for such a delivery system include small size, appropriate flexibility, and biodegradability. We have developed biodegradable PLGA-based implants for controlled intracochlear drug release that can also be used in combination with cochlear implants (CIs), which are implantable neurosensory prosthesis for hearing rehabilitation. The drug carrier system was tested for implantation in the human inner ear in 11 human temporal bones. In five of the temporal bones, CI arrays from different manufacturers were implanted before insertion of the biodegradable PLGA implants. The drug carrier system and CI arrays were implanted into the scala tympani through the round window. Implanted temporal bones were evaluated by ultra-high-resolution computed tomography (µ-CT) to illustrate the position of implanted electrode carriers and the drug carrier system. The µ-CT measurements revealed the feasibility of implanting the PLGA implants into the scala tympani of the human inner ear and co-administration of the biodegradable PLGA implant with a CI array. Graphical abstract

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