Site-Specific Formation of Gastric Ulcers by the Electric Stimulation of the Left or Right Gastric Branch of the Vagus Nerve in the Rat

1990 ◽  
Vol 25 (8) ◽  
pp. 834-840 ◽  
Author(s):  
T. Okumura ◽  
A. Uehara ◽  
K. Okamura ◽  
M. Namiki
Keyword(s):  
Vagus Nerve ◽  
Electric Stimulation ◽  
Gastric Ulcers ◽  
Site Specific ◽  
Stimulation Of

Localization of Spontaneous Respiratory Neuronal Activities in the Medulla Oblongata of the Cat: A New Location of the Expiratory Center

1957 ◽  
Vol 190 (2) ◽  
pp. 350-355 ◽  
Author(s):  
Edgar Haber ◽  
Kurt W. Kohn ◽  
S. H. Ngai ◽  
D. A. Holaday ◽  
S. C. Wang
Keyword(s):  
Vagus Nerve ◽  
Reticular Formation ◽  
Medulla Oblongata ◽  
Electric Stimulation ◽  
The Other ◽  
Drug Induced ◽  
Other Hand ◽  
Twin Beam ◽  
New Location ◽  
Stimulation Of

Medulla oblongata of 80 vagotomized cats was explored with microelectrodes. Spontaneous respiratory neuronal activities and chest movements were recorded simultaneously with a twin beam cathode ray oscilloscope. It was found that inspiratory discharges are concentrated in the reticular formation between 3 mm rostral and 1 mm caudal to the level of the obex, which corresponds approximately to the inspiratory region of Pitts, Magoun and Ranson. On the other hand, expiratory discharges are not obtained in Pitts' expiratory area, but are found in a circumscribed region in the reticular formation from the level of the obex to 3 mm caudally. Electric stimulation of this region has been found recently by Ngai and Wang to yield marked expiratory spasm. It is concluded that the expiratory center is located caudally to the inspiratory center in the cat. The spontaneous respiratory neuronal discharges continue with no alterations of pattern of firing during drug-induced respiratory paralysis, and are increased both in number and in frequency during CO2 inhalation. Stimulation of the vagus nerve with 50 shocks/sec. reduces inspiratory discharges and prolongs the duration of expiratory discharges.

scholarly journals Electric stimulation of the vagus nerve reduced mouse neuroinflammation induced by lipopolysaccharide

2016 ◽  
Vol 13 (1) ◽  
Author(s):  
G. Meneses ◽  
M. Bautista ◽  
A. Florentino ◽  
G. Díaz ◽  
G. Acero ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Electric Stimulation ◽  
Stimulation Of

Trophic maintenance of the diaphragm by various nerves

1959 ◽  
Vol 197 (3) ◽  
pp. 511-514 ◽  
Author(s):  
N. C. Jefferson ◽  
T. Ogawa ◽  
J. Toman ◽  
W. Scruggs ◽  
H. Necheles
Keyword(s):  
Vagus Nerve ◽  
Phrenic Nerve ◽  
Respiratory Function ◽  
Electric Stimulation ◽  
Spontaneous Respiration ◽  
Histologic Study ◽  
Stimulation Of

In dogs, the central end of the cut phrenic or vagus nerve was anastomosed to the distal end of the phrenic nerve. After phreno-phrenic anastomosis, slight atrophy of the muscle and nerve elements of the diaphragm occurred up to 7–8 weeks, followed by regeneration. At that time, electric stimulation of the nerve above the anastomosis produced contraction of the diaphragm, although respiratory function was absent. Ten to eleven weeks after anastomosis, spontaneous respiration recurred. In the case of vagophrenic anastomosis, spontaneous respiration did not reappear within 58 weeks, but stimulation of the vagus above the anastomosis produced contraction of the diaphragm, and histologic study showed regeneration of muscle and nerve elements. It is concluded, that trophic maintenance of the diaphragm depends on the presence of functionable innervation, not necessarily on functioning innervation.

scholarly journals Electrical Stimulation of Injected Muscles to Boost Botulinum Toxin Effect on Spasticity: Rationale, Systematic Review and State of the Art

Toxins ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 303
Author(s):  
Alessandro Picelli ◽  
Mirko Filippetti ◽  
Giorgio Sandrini ◽  
Cristina Tassorelli ◽  
Roberto De Icco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Electrical Stimulation ◽  
Botulinum Toxin ◽  
Current Literature ◽  
Electric Stimulation ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Botulinum Toxins ◽  
Stimulation Of

Botulinum toxin type A (BoNT-A) represents a first-line treatment for spasticity, a common disabling consequence of many neurological diseases. Electrical stimulation of motor nerve endings has been reported to boost the effect of BoNT-A. To date, a wide range of stimulation protocols has been proposed in the literature. We conducted a systematic review of current literature on the protocols of electrical stimulation to boost the effect of BoNT-A injection in patients with spasticity. A systematic search using the MeSH terms “electric stimulation”, “muscle spasticity” and “botulinum toxins” and strings “electric stimulation [mh] OR electrical stimulation AND muscle spasticity [mh] OR spasticity AND botulinum toxins [mh] OR botulinum toxin type A” was conducted on PubMed, Scopus, PEDro and Cochrane library electronic databases. Full-text articles written in English and published from database inception to March 2021 were included. Data on patient characteristics, electrical stimulation protocols and outcome measures were collected. This systematic review provides a complete overview of current literature on the role of electrical stimulation to boost the effect of BoNT-A injection for spasticity, together with a critical discussion on its rationale based on the neurobiology of BoNT-A uptake.

scholarly journals Selective stimulation of the ferret abdominal vagus nerve with multi-contact nerve cuff electrodes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jonathan A. Shulgach ◽  
Dylan W. Beam ◽  
Ameya C. Nanivadekar ◽  
Derek M. Miller ◽  
Stephanie Fulton ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Nerve Fibers ◽  
The Body ◽  
Evoked Responses ◽  
Gi Tract ◽  
Selective Stimulation ◽  
Nerve Cuff ◽  
Cuff Electrodes ◽  
Nerve Cuff Electrodes ◽  
Stimulation Of

AbstractDysfunction and diseases of the gastrointestinal (GI) tract are a major driver of medical care. The vagus nerve innervates and controls multiple organs of the GI tract and vagus nerve stimulation (VNS) could provide a means for affecting GI function and treating disease. However, the vagus nerve also innervates many other organs throughout the body, and off-target effects of VNS could cause major side effects such as changes in blood pressure. In this study, we aimed to achieve selective stimulation of populations of vagal afferents using a multi-contact cuff electrode wrapped around the abdominal trunks of the vagus nerve. Four-contact nerve cuff electrodes were implanted around the dorsal (N = 3) or ventral (N = 3) abdominal vagus nerve in six ferrets, and the response to stimulation was measured via a 32-channel microelectrode array (MEA) inserted into the left or right nodose ganglion. Selectivity was characterized by the ability to evoke responses in MEA channels through one bipolar pair of cuff contacts but not through the other bipolar pair. We demonstrated that it was possible to selectively activate subpopulations of vagal neurons using abdominal VNS. Additionally, we quantified the conduction velocity of evoked responses to determine what types of nerve fibers (i.e., Aδ vs. C) responded to stimulation. We also quantified the spatial organization of evoked responses in the nodose MEA to determine if there is somatotopic organization of the neurons in that ganglion. Finally, we demonstrated in a separate set of three ferrets that stimulation of the abdominal vagus via a four-contact cuff could selectively alter gastric myoelectric activity, suggesting that abdominal VNS can potentially be used to control GI function.

Electrical Stimulation of the Vagus Nerve Modulates the Development of Oxygen Epilepsy in Rabbits

2017 ◽  
Vol 47 (3) ◽  
pp. 345-351
Author(s):  
S. Yu. Zhilyaev ◽  
A. N. Moskvin ◽  
T. F. Platonova ◽  
I. T. Demchenko
Keyword(s):  
Electrical Stimulation ◽  
Vagus Nerve ◽  
Stimulation Of
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