Extreme prematurity or pulmonary hypoplasia: The inevitable consequences of second trimester premature rupture of membranes?

1993 ◽  
Vol 13 (5) ◽  
pp. 320-328 ◽  
Author(s):  
P. J. Robson ◽  
M. Smid ◽  
S. Bannerjee ◽  
J. S. Wigglesworth ◽  
U. Nicolini
Keyword(s):  
Pulmonary Hypoplasia ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Extreme Prematurity

Risk factors for pulmonary hypoplasia in second-trimester premature rupture of membranes

1994 ◽  
Vol 170 (5) ◽  
pp. 1359-1364 ◽  
Author(s):  
Patrizia Vergani ◽  
Alessandro Ghidini ◽  
Anna Locatelli ◽  
Maria Cavallone ◽  
Ivana Ciarla ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Hypoplasia ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture

Risk factors for pulmonary hypoplasia in second-trimester premature rupture of membranes

1994 ◽  
Vol 170 (5) ◽  
pp. 1359-1364 ◽  
Author(s):  
Patrizia Vergani ◽  
Alessandro Ghidini ◽  
Anna Locatelli ◽  
Maria Cavallone ◽  
Ivana Ciarla ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Hypoplasia ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture

scholarly journals Lactobacillus iners Is Associated with Vaginal Dysbiosis in Healthy Pregnant Women: A Preliminary Study

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Nengneng Zheng ◽  
Renyong Guo ◽  
Yinyu Yao ◽  
Meiyuan Jin ◽  
Yiwen Cheng ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Vaginal Microbiota ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Third Trimester ◽  
Premature Rupture ◽  
Significant Difference ◽  
Bacterial Marker ◽  
Preliminary Study ◽  
Adverse Pregnancy

Vaginal dysbiosis has been identified to be associated with adverse pregnancy outcomes, such as preterm delivery and premature rupture of membranes. However, the overall structure and composition of vaginal microbiota in different trimesters of the pregnant women has not been fully elucidated. In this study, the physiological changes of the vaginal microbiota in healthy pregnant women were investigated. A total of 83 healthy pregnant participants were enrolled, who are in the first, second, or third pregnancy trimester. Quantitative real-time PCR was used to explore the abundant bacteria in the vaginal microbiota. No significant difference in the abundance of Gardnerella, Atopobium, Megasphaera, Eggerthella, Leptotrichia/Sneathia, or Prevotella was found among different trimesters, except Lactobacillus. Compared with the first pregnancy trimester, the abundance of L. iners decreased in the second and third trimester while the abundance of L. crispatus was increased in the second trimester. Moreover, we also found that vaginal cleanliness is correlated with the present of Lactobacillus, Atopobium, and Prevotella and leukocyte esterase is associated with Lactobacillus, Atopobium, Gardnerella, Eggerthella, Leptotrichia/Sneathia, and Prevotella. For those whose vaginal cleanliness raised or leukocyte esterase became positive, the richness of L. iners increased, while that of L. crispatus decreased significantly. Our present data indicated that the altered vaginal microbiota, mainly Lactobacillus, could be observed among different trimesters of pregnancy and L. iners could be considered as a potential bacterial marker for evaluating vaginal cleanliness and leukocyte esterase.

scholarly journals Inhaled Nitric Oxide for Preterm Premature Rupture of Membranes, Oligohydramnios, and Pulmonary Hypoplasia

2008 ◽  
Vol 26 (04) ◽  
pp. 317-322 ◽  
Author(s):  
Valerie Chock ◽  
Krisa Van Meurs ◽  
Susan Hintz ◽  
Richard Ehrenkranz ◽  
James Lemons ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Hypoplasia ◽  
Inhaled Nitric Oxide ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture

scholarly journals Maternal exposure to ambient fine particulate matter and risk of premature rupture of membranes in Wuhan, Central China: a cohort study

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Kun Wang ◽  
Yu Tian ◽  
Huabo Zheng ◽  
Shengshuai Shan ◽  
Xiaofang Zhao ◽  
...  
Keyword(s):  
Cohort Study ◽  
Additive Model ◽  
Final Analysis ◽  
First Trimester ◽  
Maternal Exposure ◽  
Central China ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Third Trimester ◽  
Premature Rupture

Abstract Background The associations between maternal exposure to ambient PM2.5 during pregnancy and the risk of premature rupture of membranes (PROM) and preterm premature rupture of membranes (PPROM) are controversial. And no relevant study has been conducted in Asia. This study aimed to determine the association between maternal exposure to ambient PM2.5 during pregnancy and the risk of (P)PROM. Methods A cohort study including all singleton births in a hospital located in Central China from January 2015 through December 2017 was conducted. Multivariable logistic regression models, stratified analysis, generalized additive model, and two-piece-wise linear regression were conducted to evaluate how exposure to ambient PM2.5 during pregnancy is associated with the risks of PROM and PPROM. Results A total of 4364 participants were included in the final analysis, where 11.71 and 2.34% of births were complicated by PROM and PPROM, respectively. The level of PM2.5 exhibited a degree of seasonal variation, and its median concentrations were 63.7, 59.3, 55.8, and 61.8 μg/m3 for the first trimester, second trimester, third trimester, and the whole duration of pregnancy, respectively. After adjustment for potential confounders, PROM was positively associated with PM2.5 exposure (per 10 μg/m3) [Odds Ratio (OR) = 1.14, 95% Confidence Interval (CI), 1.02–1.26 for the first trimester; OR = 1.09, 95% CI, 1.00–1.18 for the second trimester; OR = 1.13, 95% CI, 1.03–1.24 for the third trimester; OR = 1.35, 95% CI, 1.12–1.63 for the whole pregnancy]. PPROM had positive relationship with PM2.5 exposure (per 10 μg/m3) (OR = 1.17, 95% CI, 0.94–1.45 for first trimester; OR = 1.11, 95% CI, 0.92–1.33 for second trimester; OR = 1.19, 95% CI, 0.99–1.44 for third trimester; OR = 1.53, 95% CI, 1.03–2.27 for the whole pregnancy) Positive trends between the acute exposure window (mean concentration of PM2.5 in the last week and day of pregnancy) and risks of PROM and PPROM were also observed. Conclusions Exposure to ambient PM2.5 during pregnancy was associated with the risk of PROM and PPROM.

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