Relationship between quality-of-life after 1-year follow-up and severity of traumatic brain injury assessed by computerized tomography

Brain Injury ◽  
2016 ◽  
Vol 30 (4) ◽  
pp. 441-451 ◽  
Author(s):  
Miguel Angel Prieto-Palomino ◽  
Emilio Curiel-Balsera ◽  
Maria Dolores Arias-Verdú ◽  
Monica Delange-Van Der Kroft ◽  
Alfonso Muñoz-López ◽  
...  
2008 ◽  
Vol 2 (4) ◽  
pp. 240-249 ◽  
Author(s):  
Jay Jagannathan ◽  
David O. Okonkwo ◽  
Hian Kwang Yeoh ◽  
Aaron S. Dumont ◽  
Dwight Saulle ◽  
...  

Object The management strategies and outcomes in pediatric patients with elevated intracranial pressure (ICP) following severe traumatic brain injury (TBI) are examined in this study. Methods This study was a retrospective review of a prospectively acquired pediatric trauma database. More than 750 pediatric patients with brain injury were seen over a 10-year period. Records were retrospectively reviewed to determine interventions for correcting ICP, and surviving patients were contacted prospectively to determine functional status and quality of life. Only patients with 2 years of follow-up were included in the study. Results Ninety-six pediatric patients (age range 3–18 years) were identified with a Glasgow Coma Scale score < 8 and elevated ICP > 20 mm Hg on presentation. The mean injury severity score was 65 (range 30–100). All patients were treated using a standardized head injury protocol. The mean time course until peak ICP was 69 hours postinjury (range 2–196 hours). Intracranial pressure control was achieved in 82 patients (85%). Methods employed to achieve ICP control included maximal medical therapy (sedation, hyperosmolar therapy, and paralysis) in 34 patients (35%), ventriculostomy in 23 patients (24%), and surgery in 39 patients (41%). Fourteen patients (15%) had refractory ICP despite all interventions, and all of these patients died. Seventy-two patients (75%) were discharged from the hospital, whereas 24 (25%) died during hospitalization. Univariate and multivariate analysis revealed that the presence of vascular injury, refractory ICP, and cisternal effacement at presentation had the highest correlation with subsequent death (p < 0.05). Mean follow-up was 53 months (range 11–126 months). Three patients died during the follow-up period (2 due to infections and 1 committed suicide). The mean 2-year Glasgow Outcome Scale score was 4 (median 4, range 1–5). The mean patient competency rating at follow-up was 4.13 out of 5 (median 4.5, range 1–4.8). Univariate analysis revealed that the extent of intracranial and systemic injuries had the highest correlation with long-term quality of life (p < 0.05). Conclusions Controlling elevated ICP is an important factor in patient survival following severe pediatric TBI. The modality used for ICP control appears to be less important. Long-term follow-up is essential to determine neurocognitive sequelae associated with TBI.


2021 ◽  
Author(s):  
Muhammad Zafrullah Arifin ◽  
Yulius Hermanto ◽  
Agung Budi Sutiono

Abstract Introduction Traumatic brain injury (TBI) is the main cause of death in motor-vehicle accidents. Investigation on the quality of life in patients with TBI would provide essential information for the society and policy makers in seeking the optimum ways to manage this devastating injury. Methods A total 178 of patients were involved in this study, consists of 97 patients with TBI and 81 non-TBI patients. The patients’ quality of life was evaluated by using Euroqol 5D (EQ-5D) up to 3 months of follow up. Then, the results of EQ-5D were analyzed. ResultsImpairment in mobility was more profound in patients with TBI compared to non-TBI patients (23.38% vs 9.38%, p = 0.0414). In line with the impaired mobility, impairment of self-care was also more frequently observed in patients with TBI compared to non-TBI patients (25.97% vs 12.50%, p = 0.0459). Meanwhile, the other dimensions of EQ-5D were not distinct between patients with TBI and non-TBI patients (p > 0.05). There was a trend of quality of life improvement in patients with TBI during the follow up. ConclusionPatients with TBI are more likely to experience impairment in mobility and self-care compared to non-TBI patients. Hence, TBI potentially affect quality of life.


Brain Injury ◽  
2012 ◽  
Vol 26 (2) ◽  
pp. 183-187 ◽  
Author(s):  
Xue-Bin Hu ◽  
Zhe Feng ◽  
Yu-Cong Fan ◽  
Zhi-Yong Xiong ◽  
Qi-Wei Huang

2013 ◽  
Vol 119 (6) ◽  
pp. 1566-1575 ◽  
Author(s):  
Stephen Honeybul ◽  
Courtney Janzen ◽  
Kate Kruger ◽  
Kwok M. Ho

Object The object of this study was to assess the long-term outcome and quality of life of patients who have survived with severe disability following decompressive craniectomy for severe traumatic brain injury (TBI). Methods The authors assessed outcome beyond 3 years among a cohort of 39 patients who had been adjudged either severely disabled or in vegetative state 18 months after decompressive craniectomy for TBI. Assessments performed included the Extended Glasgow Outcome Scale, modified Barthel Index (mBI), Zarit Burden Interview, and 36-Item Short-Form Health Survey (SF-36). The issue of retrospective consent for surgery was also assessed. Results Of the 39 eligible patients, 7 died, 12 were lost to follow-up, and 20 patients or their next of kin consented to participate in the study. Among those 20 patients, 5 in a vegetative state at 18 months remained so beyond 3 years, and the other 15 patients remained severely disabled after a median follow-up of 5 years. The patients' average daily activity per the mBI (Pearson correlation coefficient [r] = −0.661, p = 0.01) and SF-36 physical score (r = −0.543, p = 0.037) were inversely correlated with the severity of TBI. However, the SF-36 mental scores of the patients were reasonably high (median 46, interquartile range 37–52). The majority of patients and their next of kin believed that they would have provided consent for surgical decompression even if they had known the eventual outcome. Conclusions Substantial physical recovery beyond 18 months after decompressive craniectomy for severe TBI was not observed; however, many patients appeared to have recalibrated their expectations regarding what they believed to be an acceptable quality of life.


2019 ◽  
Author(s):  
Katrin Rauen ◽  
Lara Reichelt ◽  
Philipp Probst ◽  
Barbara Sch&auml;pers ◽  
Friedemann M&uuml;ller ◽  
...  

2017 ◽  
Vol 32 (5) ◽  
pp. 692-704 ◽  
Author(s):  
Camille Chesnel ◽  
Claire Jourdan ◽  
Eleonore Bayen ◽  
Idir Ghout ◽  
Emmanuelle Darnoux ◽  
...  

Objective: To evaluate the patient’s awareness of his or her difficulties in the chronic phase of severe traumatic brain injury (TBI) and to determine the factors related to poor awareness. Design/Setting/Subjects: This study was part of a larger prospective inception cohort study of patients with severe TBI in the Parisian region (PariS-TBI study). Intervention/Main measures: Evaluation was carried out at four years and included the Brain Injury Complaint Questionnaire (BICoQ) completed by the patient and his or her relative as well as the evaluation of impairments, disability and quality of life. Results: A total of 90 patient-relative pairs were included. Lack of awareness was measured using the unawareness index that corresponded to the number of discordant results between the patient and relative in the direction of under evaluation of difficulties by the patient. The only significant relationship found with lack of awareness was the subjective burden perceived by the relative (Zarit Burden Inventory) ( r = 0.5; P < 0.00001). There was no significant relationship between lack of awareness and injury severity, pre-injury socio-demographic data, cognitive impairments, mood disorders, functional independence (Barthel index), global disability (Glasgow Outcome Scale), return to work at four years or quality of life (Quality Of Life after Brain Injury scale (QOLIBRI)). Conclusion: Lack of awareness four years post severe TBI was not related to the severity of the initial trauma, sociodemographic data, the severity of impairments, limitations of activity and participation, or the patient’s quality of life. However, poor awareness did significantly influence the weight of the burden perceived by the relative.


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