Structures and Strategies for General Practice Research in the United Kingdom

1993 ◽  
Vol 11 (sup2) ◽  
pp. 10-12
Author(s):  
Roger Jones
2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Hershel Jick ◽  
Dean S. MacLaughlin ◽  
Pascal Egger ◽  
Peter Wiggins

Background. Initially the course of the 2009 swine flu pandemic was uncertain and impossible to predict with any confidence. An effective prospective data resource exists in the United Kingdom (UK) that could have been utilized to describe the scope and extent of the swine flu outbreak as it unfolded. We describe the 2009 swine flu outbreak in the UK as recorded daily by general practitioners and the potential use of this database for real-time tracking of flu outbreaks. Methods. Using the General Practice Research Database, a real-time general practice, electronic database, we estimated influenza incidence from July 1998 to September 2009 according to age, region, and calendar time. Results. From 1998 to2008, influenza outbreaks regularly occurred yearly from October to March, but did not typically occur from April to September until the swine flu outbreak began in April 2009. The weekly incidence rose gradually, peaking at the end of July, and the outbreak had largely dissipated by early September. Conclusions. The UK swine flu outbreak, recorded in real time by a large group of general practitioners, was mild and limited in time. Simultaneous online access seemed feasible and could have provided additional clinical-based evidence at an early planning stage of the outbreak.


2002 ◽  
Vol 63 (9) ◽  
pp. 758-762 ◽  
Author(s):  
Cynthia J. Kornegay ◽  
Catherine Vasilakis-Scaramozza ◽  
Hershel Jick

2008 ◽  
Vol 137 (1) ◽  
pp. 38-47 ◽  
Author(s):  
A. GAUTHIER ◽  
J. BREUER ◽  
D. CARRINGTON ◽  
M. MARTIN ◽  
V. RÉMY

SUMMARYRecent information on epidemiology and management of herpes zoster (HZ) and post-herpetic neuralgia (PHN), a painful complication of HZ, is scarce. The objective of this study was to document the burden of HZ and PHN in the United Kingdom. This retrospective analysis of the UK General Practice Research Database aimed to estimate HZ incidence and proportion of HZ patients developing PHN and to assess management costs in immunocompetent individuals aged ⩾50 years. A cohort of 27 225 HZ patients was selected, corresponding to an incidence of 5·23/1000 person-years. Respectively 19·5% and 13·7% of patients developed PHN at least 1 and 3 months after HZ diagnosis. Mean direct cost was £103 per HZ patient and £341 and £397 per PHN episode (1- and 3-month definition respectively). Both HZ and PHN costs increased markedly with pain severity. This study confirms that HZ and PHN are frequent and costly diseases in the United Kingdom.


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