Dried Molasses as a Direct Compression Matrix for Oral Controlled Release Drug Delivery II: Release Mechanism and Characteristics of Theophylline from a Molasses-Hpmc Matrix

The term control release means the release of the molecules from any reservoir in very precise and constant amounts and following zero-order or near-to-zero-order release kinetics. This type of formulation and device has a huge market over the medical world. The basic foundation of sustained release drug delivery system enhances the biopharmaceutical and pharmacodynamics pharmacokinetic properties of a drug in such a way that its usefulness is exploited, side-effects are reduced, and cure of the disease is attained easily. The international controlled-release drug delivery technology market has been divided on the basis of technology, application, release mechanism, and geography. This chapter describes these topics: metered dose inhalers, transdermal and ocular patches, drug eluting stents, activation-modulated drug delivery systems, polymer coating systems microelectromechanical technology, implants, micro reservoir partition controlled drug delivery systems, hydrophilic polymer matrix systems, targeted delivery, enzyme activated device.

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Chitosan based Controlled Release Drug Delivery of Mycophenolate Mofetil Loaded in Nanocarriers System: Synthesis and in-vitro evaluation

Drug Development and Industrial Pharmacy ◽

10.1080/03639045.2021.1892739 ◽

2021 ◽

pp. 1-18

Author(s):

Muhammad Zaman ◽

Asma Iqbal ◽

Syed Farhan Haider Rizvi ◽

Muhammad Ajaz Hussain ◽

Talha Jamshaid ◽

...

Keyword(s):

Drug Delivery ◽

Mycophenolate Mofetil ◽

Controlled Release ◽

In Vitro Evaluation ◽

System Synthesis ◽

Release Drug

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Carrier-Free Microspheres of an Anti-Cancer Drug Synthesized via a Sodium Catalyst for Controlled-Release Drug Delivery

Materials ◽

10.3390/ma11020281 ◽

2018 ◽

Vol 11 (2) ◽

pp. 281 ◽

Cited By ~ 5

Author(s):

Yong Xie ◽

Xinxin Ma ◽

Xujie Liu ◽

Qingming Long ◽

Yu Wang ◽

...

Keyword(s):

Drug Delivery ◽

Controlled Release ◽

Cancer Drug ◽

Release Drug ◽

Anti Cancer ◽

Carrier Free

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Optimizing Oral Controlled Release Drug Delivery Systems Using Experimental Designs

Intellectual Property Rights Open Access ◽

10.4172/2375-4516.1000142 ◽

2015 ◽

Vol 03 (02) ◽

Author(s):

Sahilhusen I Jethara ◽

Mukesh R Patel

Keyword(s):

Drug Delivery ◽

Controlled Release ◽

Drug Delivery Systems ◽

Delivery Systems ◽

Experimental Designs ◽

Release Drug

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PREPARATION AND EVALUATION OF CHITOSAN SODIUM ALGINATE CARBAMAZEPINE MICROSPHERES

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i3.16145 ◽

2017 ◽

Vol 10 (3) ◽

pp. 271 ◽

Cited By ~ 1

Author(s):

Sreeja C Nair ◽

Karthika Ramesh ◽

Krishnapriya M ◽

Asha Paul

Keyword(s):

Drug Delivery ◽

Particle Size ◽

Controlled Release ◽

Sodium Alginate ◽

Physical Parameters ◽

Effective Management ◽

Release Drug ◽

Conventional Drug ◽

Preparation And Evaluation ◽

Evaluation Parameters

ABSTRACTObjective: The objective behind our study is that a mucoadhesive rectal hydrogel chitosan sodium alginate carbamazepine (CBZ) microspheres forthe purpose of controlled release for the treatment of epilepsy to avoid the possible side effects.Methods: The study was conducted to formulate controlled release chitosan sodium alginate CBZ microspheres with the dispersion of CBZ into thenatural polymers chitosan and sodium alginate forming microspheres conducting along with their evaluation studies.Results: The formulated microspheres were subjected to various evaluation parameters, and all the physical parameters examined are within theacceptable limits. Further, the optimized microsphere formulation (CM5) was characterized. Hence, the developed optimized microsphere formulation(CM5) seems to be a viable substitute to conventional drug delivery system for the effective management of epilepsy.Conclusion: The prepared formulation also provides a desired CBZ loaded sodium alginate microspheres with the controlled release drug delivery.Keywords: Carbamazepine, Sodium alginate microspheres, Particle size.

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