Impact of a mindfulness stress management program on stress, anxiety, depression and quality of life in women with polycystic ovary syndrome: a randomized controlled trial

Stress ◽  
2014 ◽  
Vol 18 (1) ◽  
pp. 57-66 ◽  
Author(s):  
Charikleia Stefanaki ◽  
Flora Bacopoulou ◽  
Sarantis Livadas ◽  
Anna Kandaraki ◽  
Athanasios Karachalios ◽  
...  
2017 ◽  
Author(s):  
Mina Amiri ◽  
Fatemeh Nahidi ◽  
Davood Khalili ◽  
Razieh Bidhendi-Yarandi ◽  
Fahimeh Ramezani Tehrani

BACKGROUND Oral contraceptives (OCs) have been used as a first-line option for medical treatment in women with polycystic ovary syndrome (PCOS). Despite theoretical superiority of products containing antiandrogenic progestins compared to OCs containing levonorgestrel (LNG), the clinical advantage of these compounds remains unclear. OBJECTIVE The aim of this study was to compare the effects of OCs containing LNG with products containing antiandrogenic progestins including cyproterone acetate, drospirenone, and desogestrel on clinical, hormonal, and metabolic parameters and quality of life in women with PCOS. METHODS We conducted a 6-arm crossover randomized controlled trial with each arm including OCs containing LNG and one of those 3 OCs containing antiandrogenic progestins. The anthropometric and clinical manifestations and hormonal and biochemical parameters of participants were assessed at 6 time points including baseline, after washout period, and 3 and 6 months after intervention. RESULTS The study is ongoing and follow-up of recruited women will continue until 2018. CONCLUSIONS This study will provide scientific evidence on comparability of OCs with the various progesterones that will assist in decision making taking into account cost effectiveness. CLINICALTRIAL Iranian Registry of Clinical Trials IRCT201702071281N2; http://www.irct.ir/searchresult.php? keyword=&id=1281&number=2&prt=12869&total=10&m=1 (Archived by WebCite at http://www.webcitation.org/6tSP8FNWo)


2016 ◽  
Vol 26 (2) ◽  
pp. 222-230 ◽  
Author(s):  
Roy A. Willems ◽  
Catherine A. W. Bolman ◽  
Ilse Mesters ◽  
Iris M. Kanera ◽  
Audrey A. J. M. Beaulen ◽  
...  

2020 ◽  
Author(s):  
Mimi Mun Yee Tse ◽  
Yajie LI ◽  
Shuk Kwan Tang ◽  
Shamay Sheung Mei Ng ◽  
Xue Bai ◽  
...  

Abstract Background Chronic pain is common among nursing home residents and they may have difficulty seeking out pain management strategies. Due to the limitation of healthcare resources, peer support model was proved with promising effect in managing chronic conditions. Methods It is a clustered randomized controlled trial. Peer-led pain management program was provided for the experimental group. Pain situation, depression, quality of life, non-drug strategies used and pain knowledge were measured. Results Totally 262 participants joined the study. Their overall pain score was 6.36. Leg was the most frequently reported site of pain and walking ability was interfered. Depression was also reported by the participants. The score for quality of life was 32.65 for physical component and 51.58 for mental component. The mean score for pain knowledge was 46.81 out of 100. No significant difference was shown between two groups at baseline. Discussion Severe pain intensity and low self-efficacy among the participants indicated it is necessary to provide pain management programs especially for this population. The frequency with strategies applied were significantly correlated with pain intensity, pain interference, depression, and quality of life. Pain knowledge also correlated significantly with some strategies.


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