The Relationship between Coronary Artery Calcification as Assessed by Multi-Detector Computed Tomography and Arterial Stiffness

2011 ◽  
Vol 33 (8) ◽  
pp. 501-505 ◽  
Author(s):  
Jin-Sun Park ◽  
Un-Jung Choi ◽  
Hong-Seok Lim ◽  
Byoung-Joo Choi ◽  
So-Yeon Choi ◽  
...  
2009 ◽  
Vol 16 (3) ◽  
pp. 181
Author(s):  
Mi Ra Cho ◽  
Young Eun Park ◽  
Seung Hoon Baek ◽  
Joung Wook Lee ◽  
Geun Tae Kim ◽  
...  

2018 ◽  
Vol 17 (1) ◽  
pp. 92-98
Author(s):  
Salvatore Cappabianca ◽  
Maria Paola Belfiore ◽  
Alfonso Reginelli ◽  
Raffaella Capasso ◽  
Alessandra Del Prete ◽  
...  

Background: Coronary Artery Calcifications (CACs) are associated with coronary atherosclerosis and Cardiovascular (CV) events. In “non-cardiovascular” settings, CACs can be easily detected on chest Multi-Detector Computed Tomography (MDCT). Their evaluation may help to better stratify CV risk in the general population, especially for primary prevention. </P><P> Aims: We retrospectively evaluated the relationship between CAC distribution and CV risk, determined by Framingham Risk Score (FRS), in a cohort of patients who underwent chest MDCT performed for several clinical indications. </P><P> Method: We retrospectively recruited 305 patients (194 men, 111 women; mean age 70.5 years) from 3 different Italian centres. Patients with coronary stent, pacemaker and/or CV devices were excluded from the study. Circumflex Artery (LCX), Left Main Coronary Artery (LMCA), left Anterior Descending artery (LAD) and right coronary artery (RCA) were analysed. </P><P> Results: From a total population of 305 patients, 119 (39%) had low FRS (<10%), 115 (38%) had intermediate FRS (10-20%), and 71 (23%) had high FRS (>20%). The study identified 842 CACs located in decreasing order as follows: RCA (34.5%), LAD (32.3%), LCX (28%) and LMCA (13%). Statistical two-step analysis subdivided patients into two clusters according to FRS (risk threshold = 12.38%): cluster I (mean 9.34) and cluster II (mean 15.09). A significant association between CAC distribution and cluster II was demonstrated. CACs were mostly detected in patients with intermediate FRS. All patients (100%) with the highest CV risk showed intermediate RCA and LMCA involvement. </P><P> Conclusion: Radiologists can note the distribution of CACs on a chest MDCT and should mandatorily record them in their reports. Depending on CAC presence and location, these findings may have important clinical implications, mostly in asymptomatic patients with intermediate FRS. This information may reclassify a patients’ CV risk and improve clinical management.


Medicina ◽  
2021 ◽  
Vol 57 (8) ◽  
pp. 807
Author(s):  
Chien-Chih Chen ◽  
Wei-Chien Hsu ◽  
Han-Ming Wu ◽  
Jiun-Yi Wang ◽  
Pei-Yu Yang ◽  
...  

Background and Objectives: There are limited data on the association between severity of non-alcoholic fatty liver disease (NAFLD) and coronary artery calcification. This study investigated sonographic diagnosed NAFLD and coronary artery calcium score (CAC) as detected by cardiac multidetector computed tomography in general populations. Materials and Methods: A total of 545 patients were enrolled in this study. NAFLD was diagnosed by ultrasonography examination and CAC score were evaluated by cardiac multidetector computed tomography. The association between NAFLD and artery calcium score stage was determined by logistic regression analysis and Spearman correlation coefficient analysis. Results: Of all the participants, 437 (80.2%) had ultrasonography-diagnosed NAFLD and 242 (44%) had coronary artery calcification (CAC > 0). After adjustment for cardiovascular risk factors, the risk of developing coronary artery calcification was 1.36-fold greater in the patients with different severity of NAFLD compared to those without NAFLD (OR = 1.36, 95% CI = 1.07–1.77, p = 0.016). The highest OR for separate coronary artery calcification was 1.98 (OR = 1.98, 95% CI = 1.37–2.87, p < 0.001) in the left main artery, and the risk was still 1.71-fold greater after adjustments (OR = 1.71, 95% CI = 1.16–2.54, p = 0.007). Conclusions: This cross-sectional study demonstrated that the severity of NAFLD was associated with the presence of significant coronary artery calcification, especially in the left main coronary artery, suggesting increasing the cardiovascular risk.


2012 ◽  
Vol 53 (4) ◽  
pp. 685 ◽  
Author(s):  
Jae Hyun Chang ◽  
Ji Yoon Sung ◽  
Ji Yong Jung ◽  
Hyun Hee Lee ◽  
Wookyung Chung ◽  
...  

2011 ◽  
Vol 22 (2) ◽  
pp. 206-208
Author(s):  
Deane L. S. Yim ◽  
Mark C. K. Hamilton ◽  
Robert M. R. Tulloh

AbstractWe report the case of an adolescent who was presented with long-standing exertional symptoms, and was diagnosed with an anomalous right coronary arterial origin arising above the commissural junction between the left and right aortic sinus, with inter-arterial and intramural compression. The precise origin of this lesion outside the aortic sinuses is unusual, and multi-detector computed tomography gave excellent definition and spatial resolution of the anomalous origin and course. It is crucial to have a high index of suspicion of exertional symptoms, as sudden death may be the first manifestation of an anomalous coronary artery.


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