Peer review reduces spin in PCORI research reports
BACKGROUNDThe Patient-Centered Outcomes Research Institute (PCORI) is obligated to peer review and to post publicly “Final Research Reports” of all funded projects. Peer review emphasizes adherence to PCORI’s Methodology Standards. As part of meeting these standards, reviewers and editors seek to minimize “spin,” defined elsewhere as “reporting practices that distort the interpretation of results and mislead readers.” METHODSTwo independent raters assessed the prevalence of spin in reports submitted for PCORI peer review by April 2018. We then assessed whether authors addressed comments about spin received during peer review. Because investigators who submit research reports before publishing journal articles might incorporate PCORI’s feedback in their journal articles, we also assessed whether spin identified during PCORI peer review was present in related journal articles.RESULTSWe included 64 projects funded by PCORI. Spin was identified during peer review in 55/64 (86%) submitted research reports. Types of spin included reporting bias (46/55; 84%), inappropriate interpretation (40/55; 73%), inappropriate extrapolation of results (15/55; 27%), and inappropriate attribution of causality (5/55; 9%). Authors addressed comments about spin in 47/55 (85%) of the revised and accepted research reports.Journal articles associated with 21/55 (38%) research reports contained spin that was also identified in the research report. PCORI comments about spin were potentially applicable to 44/110 journal articles with results. Of these, 27/44 (61%) contained spin that was also identified in the PCORI research report. The proportion of articles with spin was similar for those accepted before and after PCORI peer review.DISCUSSIONMost reports submitted to PCORI included spin, which was mitigated during peer review. We found no evidence that peer review of PCORI research reports affected spin in journal articles. Some journal articles contained spin even when authors removed spin from their PCORI research reports.When both are available, PCORI research reports might be more useful to systematic reviewers and other stakeholders compared with journal articles about the same study because they include less reporting bias and other types of spin.