scholarly journals Understanding the characteristics and mechanisms underlying suicide clusters: a comparison of cluster detection methods in Australian youth

2020 ◽  
Author(s):  
Nicole Hill ◽  
Lay San Too ◽  
Matt Spittal ◽  
Jo Robinson

Aims:There is currently no gold-standard definition or method for identifying suicide clusters, resulting in considerable heterogeneity in the types of suicide clusters that are detected. This study sought to identify the characteristics, mechanisms, and parameters of suicide clusters using three cluster detection methods. Specifically, the study aimed to: 1) determine the overlap in suicide clusters among each method; 2) compare the spatial and temporal parameters associated with different suicide clusters; and 3) identify the demographic characteristics and rates of exposure to suicide among cluster and non-cluster members.Methods: Suicide data were obtained from the National Coronial Information System. N=3027 Australians, aged 10-24 who died by suicide in 2006-2015 were included. Suicide clusters were determined using: 1) poisson scan statistics; 2) a systematic search of coronial inquests; and 3) descriptive network analysis. These methods were chosen to operationalise three different definitions of suicide clusters, namely clusters that are: 1) statistically significant; 2) perceived to be significant; and 3) characterised by social links among three or more suicide descendents. For each method, the demographic characteristics and rates of exposure to suicide were identified, in addition to the maximum duration of suicide clusters, the geospatial overlap between suicide clusters, and the overlap of individual cluster members. Results: Eight suicide clusters (69 suicides) were identified from the scan statistic, seven (40 suicides) from coronial inquests; and 11 (37 suicides) from the descriptive network analysis. Of the eight clusters detected using the scan statistic, two overlapped with clusters detected using the descriptive network analysis and one with clusters identified from coronial inquests. Of the seven clusters from coronial inquests, four overlapped with clusters from the descriptive network analysis and one with clusters from the scan statistic. Overall, 9.2% (12 suicides) of individuals were identified by more than one method. Prior exposure to suicide was 10.1% (N=7) in clusters from the scan statistic; 32.5% (N=13) in clusters from coronial inquest; and 56.8% (N=21) in clusters from the descriptive network analysis.Conclusion: Each method identified markedly different suicide clusters. Evidence of social links between cluster members was largely limited to clusters detected using the descriptive network analysis. However, these data were limited to the availability information collected as part of the police and coroner investigation. Communities tasked with detecting and responding to suicide clusters may benefit from using the spatial and temporal parameters revealed in descriptive studies to inform analyses of suicide clusters using inferential methods.

Author(s):  
N.T.M. Hill ◽  
L.S. Too ◽  
M.J. Spittal ◽  
J. Robinson

Abstract Aims There is currently no gold-standard definition or method for identifying suicide clusters, resulting in considerable heterogeneity in the types of suicide clusters that are detected. This study sought to identify the characteristics, mechanisms and parameters of suicide clusters using three cluster detection methods. Specifically, the study aimed to: (1) determine the overlap in suicide clusters among each method, (2) compare the spatial and temporal parameters associated with different suicide clusters and (3) identify the demographic characteristics and rates of exposure to suicide among cluster and non-cluster members. Methods Suicide data were obtained from the National Coronial Information System. N = 3027 Australians, aged 10–24 who died by suicide in 2006–2015 were included. Suicide clusters were determined using: (1) poisson scan statistics, (2) a systematic search of coronial inquests and (3) descriptive network analysis. These methods were chosen to operationalise three different definitions of suicide clusters, namely clusters that are: (1) statistically significant, (2) perceived to be significant and (3) characterised by social links among three or more suicide descendants. For each method, the demographic characteristics and rates of exposure to suicide were identified, in addition to the maximum duration of suicide clusters, the geospatial overlap between suicide clusters, and the overlap of individual cluster members. Results Eight suicide clusters (69 suicides) were identified from the scan statistic, seven (40 suicides) from coronial inquests; and 11 (37 suicides) from the descriptive network analysis. Of the eight clusters detected using the scan statistic, two overlapped with clusters detected using the descriptive network analysis and one with clusters identified from coronial inquests. Of the seven clusters from coronial inquests, four overlapped with clusters from the descriptive network analysis and one with clusters from the scan statistic. Overall, 9.2% (12 suicides) of individuals were identified by more than one method. Prior exposure to suicide was 10.1% (N = 7) in clusters from the scan statistic, 32.5% (N = 13) in clusters from coronial inquest and 56.8% (N = 21) in clusters from the descriptive network analysis. Conclusion Each method identified markedly different suicide clusters. Evidence of social links between cluster members typically involved clusters detected using the descriptive network analysis. However, these data were limited to the availability information collected as part of the police and coroner investigation. Communities tasked with detecting and responding to suicide clusters may benefit from using the spatial and temporal parameters revealed in descriptive studies to inform analyses of suicide clusters using inferential methods.


F1000Research ◽  
2018 ◽  
Vol 6 ◽  
pp. 1819
Author(s):  
Wongsa Laohasiriwong ◽  
Nattapong Puttanapong ◽  
Amornrat Luenam

Background: The Centers for Disease Control and Prevention reported that deaths from chronic respiratory diseases (CRDs) in Thailand increased by almost 13% in 2010, along with an increased burden related to the disease. Evaluating the geographical heterogeneity of CRDs is important for surveillance. Previous studies have indicated that socioeconomic status has an effect on disease, and that this can be measured with variables such as night-time lights (NTLs) and industrial density (ID). However, there is no understanding of how NTLs and ID correlate with CRDs. We compared spatial heterogeneity obtained by using local cluster detection methods for CRDs and by correlating NTLs and ID with CRDs. Methods: We applied the spatial scan statistic in SaTScan, as well as local indices of spatial association (LISA), Getis and Ord’s local Gi*(d) statistic, and Pearson correlation. In our analysis, data were collected on gender, age, household income, education, family size, occupation, region, residential area, housing construction materials, cooking fuels, smoking status and previously diagnosed CRDs by a physician from the National Socioeconomic Survey, which is a cross-sectional study conducted by the National Statistical Office of Thailand in 2010. Results: According to our findings, the spatial scan statistic, LISA, and the local Gi*(d) statistic revealed similar results for areas with the highest clustering of CRDs. However, the hotspots for the spatial scan statistic covered a wider area than LISA and the local Gi*(d) statistic. In addition, there were persistent hotspots in Bangkok and the perimeter provinces. NTLs and ID have a positive correlation with CRDs. Conclusions: This study demonstrates that all the statistical methods used could detect spatial heterogeneity of CRDs. NTLs and ID can serve as new parameters for determining disease hotspots by representing the population and industrial boom that typically contributes to epidemics.


F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1819 ◽  
Author(s):  
Wongsa Laohasiriwong ◽  
Nattapong Puttanapong ◽  
Amornrat Luenam

Background: The Centers for Disease Control and Prevention reported that deaths from chronic respiratory diseases (CRDs) in Thailand increased by almost 13% in 2010, along with an increased burden related to the disease. Evaluating the geographical heterogeneity of CRDs is important for surveillance. Previous studies have indicated that socioeconomic status has an effect on disease, and that this can be measured with variables such as night-time lights (NTLs) and industrial density (ID). However, there is no understanding of how NTLs and ID correlate with CRDs. We compared spatial heterogeneity obtained by using local cluster detection methods for CRDs and by correlating NTLs and ID with CRDs. Methods: We applied the spatial scan statistic in SaTScan, as well as local indices of spatial association (LISA), Getis and Ord’s local Gi*(d) statistic, and Pearson correlation. In our analysis, data were collected on gender, age, household income, education, family size, occupation, region, residential area, housing construction materials, cooking fuels, smoking status and previously diagnosed CRDs by a physician from the National Socioeconomic Survey, which is a cross-sectional study conducted by the National Statistical Office of Thailand in 2010. Results: According to our findings, the spatial scan statistic, LISA, and the local Gi*(d) statistic revealed similar results for areas with the highest clustering of CRDs. However, the hotspots for the spatial scan statistic covered a wider area than LISA and the local Gi*(d) statistic. In addition, there were persistent hotspots in Bangkok and the perimeter provinces. NTLs and ID have a positive correlation with CRDs. Conclusions: This study demonstrates that all the statistical methods used could detect spatial heterogeneity of CRDs. NTLs and ID can serve as new parameters for determining disease hotspots by representing the population and industrial boom that typically contributes to epidemics.


2015 ◽  
Vol 4 (1) ◽  
pp. 367-384 ◽  
Author(s):  
Hensley Mariathas ◽  
Rhonda Rosychuk

2009 ◽  
Vol 41 (01) ◽  
pp. 13-37 ◽  
Author(s):  
Zakhar Kabluchko ◽  
Evgeny Spodarev

Let n points be chosen independently and uniformly in the unit cube [0,1] d , and suppose that each point is supplied with a mark, the marks being independent and identically distributed random variables independent of the location of the points. To each cube R contained in [0,1] d we associate its score defined as the sum of marks of all points contained in R. The scan statistic is defined as the maximum of taken over all cubes R contained in [0,1] d . We show that if the marks are nonlattice random variables with finite exponential moments, having negative mean and assuming positive values with nonzero probability, then the appropriately normalized distribution of the scan statistic converges as n → ∞ to the Gumbel distribution. We also prove a corresponding result for the scan statistic of a Lévy noise with negative mean. The more elementary cases of zero and positive mean are also considered.


2017 ◽  
Author(s):  
Barbara Więckowska ◽  
Justyna Marcinkowska

When searching for epidemiological clusters, an important tool can be to carry out one’s own research with the incidence rate from the literature as the reference level. Values exceeding this level may indicate the presence of a cluster in that location. This paper presents a method of searching for clusters that have significantly higher incidence rates than those specified by the investigator. The proposed method uses the classic binomial exact test for one proportion and an algorithm that joins areas with potential clusters while reducing the number of multiple comparisons needed. The sensitivity and specificity are preserved by this new method, while avoiding the Monte Carlo approach and still delivering results comparable to the commonly used Kulldorff’s scan statistics and other similar methods of localising clusters. A strong contributing factor afforded by the statistical software that makes this possible is that it allows analysis and presentation of the results cartographically.


2012 ◽  
Vol 49 (01) ◽  
pp. 199-209 ◽  
Author(s):  
James C. Fu ◽  
Tung-Lung Wu ◽  
W.Y. Wendy Lou

The distributions for continuous, discrete, and conditional discrete scan statistics are studied. The approach of finite Markov chain imbedding, which has been applied to random permutations as well as to runs and patterns, is extended to compute the distribution of the conditional discrete scan statistic, defined from a sequence of Bernoulli trials. It is shown that the distribution of the continuous scan statistic induced by a Poisson process defined on (0, 1] is a limiting distribution of weighted distributions of conditional discrete scan statistics. Comparisons of rates of convergence as well as numerical comparisons of various bounds and approximations are provided to illustrate the theoretical results.


2014 ◽  
Vol 20 (1) ◽  
pp. 250-253 ◽  
Author(s):  
Andry Alamsyah ◽  
Budi Rahardjo ◽  
. Kuspriyanto

2009 ◽  
Vol 138 (6) ◽  
pp. 873-883 ◽  
Author(s):  
J. STELLING ◽  
W. K. YIH ◽  
M. GALAS ◽  
M. KULLDORFF ◽  
M. PICHEL ◽  
...  

SUMMARYAntimicrobial resistance is a priority emerging public health threat, and the ability to detect promptly outbreaks caused by resistant pathogens is critical for resistance containment and disease control efforts. We describe and evaluate the use of an electronic laboratory data system (WHONET) and a space–time permutation scan statistic for semi-automated disease outbreak detection. In collaboration with WHONET-Argentina, the national network for surveillance of antimicrobial resistance, we applied the system to the detection of local and regional outbreaks of Shigella spp. We searched for clusters on the basis of genus, species, and resistance phenotype and identified 19 statistical ‘events’ in a 12-month period. Of the six known outbreaks reported to the Ministry of Health, four had good or suggestive agreement with SaTScan-detected events. The most discriminating analyses were those involving resistance phenotypes. Electronic laboratory-based disease surveillance incorporating statistical cluster detection methods can enhance infectious disease outbreak detection and response.


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