scholarly journals A Rare Association of Idiopathic Gingival Enlargement with Plasma Cell Gingivitis and Generalized Chronic Periodontitis

2021 ◽  
Vol 5 (3) ◽  
pp. 119-121
Author(s):  
Meera Mathai ◽  
◽  
V Menaka ◽  
Nusrat Siddiqui ◽  
Karthik Shunmugavelu ◽  
...  
Keyword(s):  
Plasma Cell ◽  
Chronic Periodontitis ◽  
Rare Case ◽  
Separate Entity ◽  
Older Patient ◽  
Gingival Overgrowth ◽  
Rare Association ◽  
Gingival Enlargement ◽  
Gingival Fibromatosis ◽  
Functional Problems

Gingival fibromatosis is a clinical condition that is characterized by gingival overgrowth. It is often caused due to medication, hereditary reasons and other local factors. When the etiology is unknown, they are referred as Idiopathic gingival enlargement (IGE). IGE is a rare and is often occurs as a manifestation of an underlying syndrome or as a separate entity. They clinically appear as gingival overgrowth with firm consistency with both deciduous and permanent dentition equally affected and worsens during adolescence. IGE is a slowly growing benign growth affecting all anatomic parts of the gingiva leading to esthetic and functional problems with difficulty in speech, mastication and deglutition. This leads to plaque accumulation which complicates the previous gingival enlargements. There are many cases reporting the idiopathic gingival enlargement in the literature, but here we report a rare case of non-syndromic association of IGE, chronic periodontitis and plasma cell gingivitis in an older patient.

scholarly journals Idiopathic gingival fibromatosis with massive gingival overgrowth: A rare case report

2020 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
AjoyKumar Shahi ◽  
Swati Sharma ◽  
VirendraKumar Prajapati ◽  
Bishnupati Singh
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Gingival Overgrowth ◽  
Rare Case Report ◽  
Gingival Fibromatosis

Idiopathic Gingival Enlargement and its Management: A Case Report

2015 ◽  
Vol 7 (2) ◽  
pp. 61-65
Author(s):  
Mohammad- Taghi Chitsazi ◽  
Adileh Shirmohammadi ◽  
Abouzar Moradi ◽  
Zahra goharfar
Keyword(s):  
Case Report ◽  
Chief Complaint ◽  
Gingival Overgrowth ◽  
Psychological Disturbances ◽  
Gingival Enlargement ◽  
Grade Ii ◽  
Gingival Fibromatosis ◽  
Interdental Papilla ◽  
Grade Iii

Idiopathic or hereditary gingival fibromatosis (HGF) is a relatively rare disease characterized by the enlargement of the gingiva, resulting in functional, esthetics and psychological disturbances. The degree of gingival overgrowth can be defined as: grade 0: no sign of gingival enlargement; grade I: enlargement confined to interdental papilla; grade II: enlargement involves papilla and marginal gingiva; and grade III: enlargement covers three quarters or more of the crown. This case report describes the case of a 16-year-old girl suffering from HGF with chief complaint of gingival swelling. Intraoral examination exhibited diffuse and grade III gingival enlargement in both jaws and also in both surfaces of buccal and lingual/palatal. Treatment included surgery (internal and external gingivectomy) in six sessions, and prescription of antibiotics and 0.2% chlorhexidine mouthwash. Moreover, gingivoplasty was performed in the esthetic zone of maxilla after performing all the surgeries in the mouth. The patient was under regular follow-up visits. The treatment outcomes after six months were satisfactory and no symptoms of recurrence were observed.

scholarly journals Amelogenesis Imperfecta and Generalized Gingival Overgrowth Resembling Hereditary Gingival Fibromatosis in Siblings: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Emre Yaprak ◽  
Meryem Gülce Subaşı ◽  
Mustafa Avunduk ◽  
Filiz Aykent
Keyword(s):  
Clinical Findings ◽  
Amelogenesis Imperfecta ◽  
Flap Surgery ◽  
Older Patient ◽  
Developmental Abnormalities ◽  
Gingival Enlargement ◽  
Hereditary Disorders ◽  
Gingival Fibromatosis

Amelogenesis imperfecta (AI) is a group of hereditary disorders primarily characterized by developmental abnormalities in the quantity and/or quality of enamel. There are some reports suggesting an association between AI and generalized gingival enlargement. This paper describes the clinical findings and oral management of two siblings presenting both AI and hereditary gingival fibromatosis (HGF) like generalized gingival enlargements. The treatment of gingival enlargements by periodontal flap surgery was successful in the management of the physiologic gingival form for both patients in the 3-year follow-up period. Prosthetic treatment was also satisfactory for the older patient both aesthetically and functionally.

The Effect of MMP-13, MMP-12, and AMBN on Gingival Enlargement and Root Deformation In a New Type of Gingival Fibromatosis

2018 ◽  
Vol 42 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Chung-Min Kang ◽  
Jae-Ho Lee ◽  
Mijeong Jeon ◽  
Je Seon Song ◽  
Seong-Oh Kim
Keyword(s):  
Gene Expression ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Potential Mechanism ◽  
Rt Pcr ◽  
Gingival Overgrowth ◽  
Gingival Enlargement ◽  
New Type ◽  
Gingival Fibromatosis

This case compared gene-expression between a new type of idiopathic gingival fibromatosis (IGF) and normal gingiva, to clarify the nature of the gingival overgrowth and dental anomaly. A 6-year-old girl with generalized gingival overgrowth and root deformations was diagnosed with IGF. Gene expression profiles were compared between normal gingiva (N=9) and one IGF gingiva using cDNA microarray. Genes related to regulation of cell proliferation and proteolytic degradation were expressed strongly in IGF. MMP-13 and MMP-12 expression were 120 times and 96 times lower in IGF, respectively, whereas AMBN expression was 79 times higher. RT-PCR and immunohistochemical staining supported the microarray results. Reduced proteolytic activity due to low MMP-13 and MMP-12 expression appears to be a potential mechanism for gingival overgrowth. Genetic investigations, such as expression levels of MMP-13, MMP-12, and AMBN, may enable classification of a new syndrome characterized by gingival enlargement with abnormal root development.

scholarly journals A Rare Case of Severe Amlodipine-Induced Gingival Overgrowth: A Case Report

2021 ◽  
Vol 1 (3) ◽  
Author(s):  
Marika Shahid ◽  
Yong W Lee ◽  
Gande Li ◽  
Chisom Mogbo ◽  
Roger Vega
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Gingival Overgrowth

scholarly journals Oral Contraceptives Induced Gingival Overgrowth – A Clinical Case Report

2017 ◽  
Vol 1 (1) ◽  
pp. 1-5
Author(s):  
Anushi Mahajan ◽  
Ritesh Sood
Keyword(s):  
Oral Contraceptives ◽  
Oral Hygiene ◽  
Periodontal Therapy ◽  
Response To Therapy ◽  
Drug Induced ◽  
Gingival Overgrowth ◽  
Periodontal Tissues ◽  
Hygiene Measures ◽  
Nonsurgical Periodontal Therapy ◽  
Gingival Enlargement

Aim: The purpose of this article is to report a case of drug induced gingival enlargement due to oral contraceptives, managed by nonsurgical periodontal therapy. Background: Drug-induced gingival overgrowth remains the most widespread unwanted effect of systemic medication on the periodontal tissues. Hormones are specific regulatory molecules that modulate a host of body functions. Oral contraceptives that contain estrogen and/or progesterone are associated with gingival enlargement. Report: A 32-year-old female presented with a complaint of swelling of the gingiva with spontaneous bleeding in the mandibular anterior region for a period of two years. The health history documented the use of contraceptives for two years, and a clinical examination revealed the existence of poor oral hygiene and enlarged painful gingival tissues that bled when touched. Summary: Females on oral contraceptives can be considered as a “risk group” for periodontal diseases. Not all females on oral contraceptives respond in similar way. Plaque control is the most important procedure in periodontal therapy. Although the initial picture presented the possibility of surgical intervention, the clinical problems were resolved with non-surgical treatment. Another factor contributing to response to therapy is patient compliance. The patient followed home care instructions well and was effective in personal oral hygiene measures. Keywords: Gingival enlargement, Sex hormones, Oral contraceptives.

scholarly journals A Case Report of a Gingival Plasma Cell Granuloma in a Patient on Antihypertensive Therapy: Diagnostic Enigma

2019 ◽  
Author(s):  
Ruchi Gulati ◽  
Madhu Singh Ratre ◽  
Shaleen Khetarpal ◽  
Manish Varma
Keyword(s):  
Plasma Cell ◽  
Plasma Cells ◽  
Present Report ◽  
Plasma Cell Granuloma ◽  
Provisional Diagnosis ◽  
Unique Case ◽  
Drug Induced ◽  
Gingival Overgrowth ◽  
Neoplastic Lesion ◽  
Patient Reported

The aim of the present report was to discuss a unique case of gingival plasma cell granuloma (PCG) in a hypertensive patient on Amlodipine therapy. Also, we attempt to emphasize the importance of considering primary and advance investigations before making a definite diagnosis. PCG is an extremely rare, reactive, non-neoplastic lesion characterized by the predominance of polyclonal plasma cells. Drug-induced gingival overgrowth is a known side effect of Amlodipine. A hypertensive 60-year-old female patient reported with a chief complaint of swollen gums and discomfort in the upper front teeth region. A provisional diagnosis of Amlodipine-induced gingival overgrowth, combined gingival overgrowth, and fibroma was suggested. Surprisingly, histopathology revealed it to be a plasma cell lesion which was confirmed by advanced investigations, thereby establishing a confirmatory diagnosis of PCG

scholarly journals Multiple Cranial Nerve Palsies, Without Definitive Brain Lesion. Rare Case of Plasma Cell Myeloma

2019 ◽  
Vol 33 (4) ◽  
pp. 1-3
Author(s):  
Uzma Nasim Siddiqui
Keyword(s):  
Plasma Cell ◽  
Cranial Nerve ◽  
Rare Case ◽  
Brain Lesion ◽  
Plasma Cell Myeloma ◽  
Cranial Nerve Palsies ◽  
Lytic Lesions ◽  
Organic Brain ◽  
Possible Cause ◽  
Multiple Cranial Nerve

Plasma cell myeloma rarely presents with neurological symptoms, and if this happens then cause is usually plasmacytoma. This is a very rare case to be presented as multiple cranial nerve palsies, unusual presentation of plasma cell myeloma without involvement of organic brain lesion in literature to date. A 70 years old gentleman having ESRD, was received with diplopia, deviation of angle of mouth, on and off chest pain. Investigations ruled out stroke, cardiac event, autoimmune process or any other possible cause of cranial nerve palsies. Diagnosis of multiple myeloma was confirmed by immune electrophoresis which showed monoclonal gammopathy, punched out lytic lesions were found on skeletal scurvy and later confirmation was done by bone marrow biopsy for the presence of plasma cell myeloma. Key words: plasma cell myeloma, cranial nerve palsies

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