scholarly journals The intraoperative pathological findings in cases of chronic suppurative otitis media with central perforation of tympanic membrane at a tertiary care centre in Eastern Nepal

2017 ◽  
Vol 8 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Sanjeev Kumar Thakur ◽  
Nisha Ghimire ◽  
Rabin Acharya ◽  
Sanjay Kumar Singh ◽  
Anwar Afaque
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Tertiary Care ◽  
Pure Tone Audiometry ◽  
Chronic Suppurative Otitis Media ◽  
Pathological Findings ◽  
Tertiary Care Centre ◽  
Middle Ear Mucosa ◽  
Suppurative Otitis Media ◽  
Central Perforation

Background: Chronic suppurative otitis media (CSOM) is the chronic inflammation of the middle ear cleft. The atticoantral type is called unsafe type because of the associated complications due to granulations and cholesteatoma which may be life-threatening. CSOM with central perforation (tubotympanic type) is usually not associated with major complications such as cholesteatoma formation.Aims and Objectives: To find out the intraoperative pathological findings in cases of CSOM with central perforation (tubotympanic type)Materials and Methods: This descriptive, cross sectional study has been conducted in the Department of Ear, Biratnagar Eye Hospital in Nepal over 2 years. Study group includes 172 patients having CSOM with central perforations in the tympanic membranes who underwent different types of procedures. Preoperatively, all the patients were evaluated with otoscopy, microscopy, pure-tone audiometry, and some patients with computed tomography scan. The pathological findings were confirmed with biopsy. The findings were tabulated and analysed.Results: 21(12.2%) patients were having dry central perforation with normal Eustachian tube function.  95 patients, i.e., 55.23% were having granulations in attic, aditus, antrum.  25 (14.53%) cases were having ossicular erosion.5 (2.9%) cases had tympanosclerosis in middle ear. 1 (0.58%) case had facial nerve dehiscence. 16 (9.3%) cases had oedema of middle ear mucosa/aural polyp from middle ear. Surprisingly 9 patients, i.e., 5.23% were having cholesteatoma which was confirmed by histopathological study.Conclusion: This study shows that cholesteatoma can be found in tubotympanic type of CSOM, along with other pathological findings. Hence it is on the part of the surgeon to be careful while planning surgery on their patients with CSOM (tubotympanic type), remembering that all safe CSOM might not always be safe. Asian Journal of Medical Sciences Vol.8(1) 2017 42-47

scholarly journals Investigation of the Presence of Biofilms in Chronic Suppurative Otitis Media, Nonsuppurative Otitis Media, and Chronic Otitis Media with Cholesteatoma by Scanning Electron Microscopy

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Ercan Kaya ◽  
Ilknur Dag ◽  
Armagan Incesulu ◽  
Melek Kezban Gurbuz ◽  
Mustafa Acar ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Otitis Media ◽  
Middle Ear ◽  
Chronic Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Middle Ear Mucosa ◽  
Suppurative Otitis Media ◽  
Tissue Samples ◽  
Scanning Electron

Objective. Biofilms have been shown to play a major role in the pathogenesis of otolaryngologic infections. However, very limited studies have been undertaken to demonstrate the presence of biofilms in tissues from patients with chronic otitis media (COM) with or without cholesteatoma. Our objective is to study the presence of biofilms in humans with chronic suppurative and nonsuppurative otitis media and cholesteatoma.Study Design. In all, 102 tissue specimens (middle ear, mastoid tissue, and ossicle samples) were collected during surgery from 34 patients.Methods. The samples were processed for the investigation of biofilms by scanning electron microscopy (SEM).Results. Our research supports the hypothesis in which biofilms are involved in chronic suppurative otitis media, cholesteatoma, and, to a lesser degree, chronic nonsuppurative otitis media. There were higher rates in hypertrophic and granulated tissue samples than in normal mucosa. In addition, the presence of biofilms was significantly higher in the middle ear mucosa compared with the mastoid and ossicle samples.Conclusion. In the clinic, the careful use of topical or systemic antimicrobials is essential, and, during surgery, hypertrophic tissue must be carefully removed from normal tissue.

scholarly journals Correlation between histomorphometric changes and the type of aerobic bacteria isolated in chronic suppurative otitis media

2011 ◽  
Vol 68 (1) ◽  
pp. 46-50
Author(s):  
Emilija Zivkovic-Marinkov ◽  
Milan Stankovic ◽  
Dragan Mihailovic ◽  
Mila Bojanovic
Keyword(s):  
Staphylococcus Aureus ◽  
Otitis Media ◽  
Middle Ear ◽  
Granulation Tissue ◽  
Bacterial Flora ◽  
Inflammatory Cells ◽  
Chronic Suppurative Otitis Media ◽  
Aerobic Bacteria ◽  
Middle Ear Mucosa ◽  
Suppurative Otitis Media

Background/Aim. Bacterial flora is a very important factor in pathogenesis of chronic suppurative otitis media (CSOM) and significantly influences the type and intensity of osteolytic process. There are few histomorphometric investigations of middle ear mucosa in chronic otitis. The aim of this study was to identify aerobic bacteria responsible for chronic suppurative otitis media as well as their association with histomorphometric changes of middle ear mucosa. Methods. A prospective study that comprised 153 patients treated in the Clinc for Ear, Thorat and Nose Diseases, Nis, was conducted. Bacteriologic analysis of diseased ear secretion was carried out in all patients. Intraoperatively removed granulation tissue was used for histomorphometry. The analysed parameters were: the number of inflammatory cells, as well as vascularization and vasodilatation. Results. The most frequently isolated aerobic bacteria from chronic suppurative otitis media were Staphylococcus aureus (29.02%), Pseudomonas aeruginosa (29.02%) and Proteus spp. (21.76%). There was no correlation between the type of pathologic process and the type of bacteria.The number of inflammatory cells in the granulation tissue in pure cultures of Staphylococcus aureus was 1,597.33 ? 549.45 and in Pseudomonas auriginosa cultures was 2,639 ? 648. Conclusion. This study showed that there is a statistically significant correlation between the number of inflammatory cells in the granulation tissue and the type of aerobic bacteria we isolated. The intensity of the infection in chronic suppurative otitis media depends on the type of the isolated bacteria, which emphasizes the importance of adequate preoperative antimicrobial therapy.

scholarly journals Mycology of Chronic Suppurative Otitis Media at Tertiary Care Centre of Nepal

2021 ◽  
Author(s):  
Ajay Kumar Chaurasiya ◽  
Rabindra Bhakta Pradhananga ◽  
Dipendra Kumar Mandal ◽  
Manoj Mahato ◽  
Niranjan Prasad Sah ◽  
...  
Keyword(s):  
Otitis Media ◽  
Potassium Hydroxide ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Chronic Suppurative Otitis Media ◽  
Fungal Culture ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Suppurative Otitis Media ◽  
Positive Growth

Abstract ObjectiveThis study was designed to find out the fungal aetiological agents in chronic suppurative otitis media (CSOM) patients attending tertiary care centre of Nepal. ResultTotal 123 samples of 117 patients, outdoor as well as indoor from Department of ENT and Head and Neck Surgery (HNS) TUTH, Maharajgunj, Kathmandu those specimens were processed and among them, 23(18.7%) was found potassium hydroxide (KOH) mount positive whereas positive growth was in 27 specimens. The prevalence rate of fungus was 21.95 percent in which the main pathogen was Aspergillus species (51.8%), followed by Candida species (14.8 %). Keywords: CSOM, KOH, Fungal culture, Aspergillus

scholarly journals Intra-operative findings of attico-antral type of chronic suppurative otitis media: A study of 85 patients.

2020 ◽  
Vol 27 (10) ◽  
pp. 2229-2234
Author(s):  
Naeem Akhtar ◽  
Muhammad Waqas ◽  
Asma Naeem
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Granulation Tissue ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Chronic Suppurative Otitis Media ◽  
Suppurative Otitis Media ◽  
Life Threatening ◽  
Operative Findings ◽  
Huge Challenge

Objectives: Chronic suppurative otitis media is the most common ear disease in Otolaryngology OPD and Head & Neck surgery in tertiary care hospitals worldwide. Due to its life threatening complications and management difficulties, attico-antral disease, a type of CSOM poses a huge challenge to otolaryngologists. Study Design: Descriptive study. Setting: Department of Otolaryngology and Head & Neck Surgery Allied Hospital (FMU) Faisalabad. Period: From January 2016 to December 2018. Material & Methods: Eighty five patients with CSOM of attico-antral type were included. Results: Forty six patients (54.1%) were male and thirty nine patients (45.9%) were female, aged 07 to 58 years with an average age of 23.7 years. 42 patients (49.4%) had a right ear disease and 43 patients (50.6%) had a left ear disease. Granulation tissue was observed in 50 patients (58.8%), cholesteatoma in 27 patients (31.7%) and both granulation tissue and cholesteatoma in 08 patients (09.5%). The main pathology was observed to involve the attic area only of 04 patients (04.7%), attic and middle ear of 44 patients (51.7%), attic and antrum of 16 patients (18.9%) and attic, middle ear, antrum and other mastoid air cells in 21 cases (24.7%). The malleus handle was found eroded in 10 patients (11.8%), head & handle in only 02 patients (02.4%). In 23 patients (27%) long process of incus was damaged while incus was completely eroded in 03 patients (03.5%). The suprastructure of stapes was found eroded in 03 patients (03.5%). Conclusion: Granulation tissue is the most common primary lesion along with cholesteatoma associated with attico-antral type of CSOM. Due to this pathology, the incus is the most frequently eroded small bone of the middle ear. In addition the management of granulation tissue and cholesteatoma poses a huge challenge to the otolaryngologists. Therefore, the general practitioners are needed to be educated for early referral to otolaryngologist for early and rapid management to prevent complications due to attico-antral type of CSOM.

Mucosal Biofilm Formation on Middle-Ear Mucosa in a Nonhuman Primate Model of Chronic Suppurative Otitis Media

2005 ◽  
Vol 115 (8) ◽  
pp. 1469-1472 ◽  
Author(s):  
Joseph E. Dohar ◽  
Patricia A. Hebda ◽  
Richard Veeh ◽  
Marie Awad ◽  
J William Costerton ◽  
...  
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Nonhuman Primate ◽  
Biofilm Formation ◽  
Chronic Suppurative Otitis Media ◽  
Nonhuman Primate Model ◽  
Primate Model ◽  
Middle Ear Mucosa ◽  
Suppurative Otitis Media
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