scholarly journals Sclerosing Stromal Tumor of Ovary: A Case Report

2017 ◽  
Vol 1 (1) ◽  
pp. 83-86
Author(s):  
R. Rana ◽  
S.U. Kafle ◽  
K.K. Jha ◽  
M. Singh ◽  
P. Gautam
Keyword(s):  
Ovarian Tumor ◽  
Past History ◽  
Young Patients ◽  
Pelvic Mass ◽  
Stromal Tumor ◽  
Histopathological Diagnosis ◽  
Malignant Ovarian Tumor ◽  
History Of ◽  
Sclerosing Stromal Tumor ◽  
Sex Cord Stromal Tumors

A case of 32 year old female of pelvic pain for one month and with past history of hysterectomy performed two year back. Clinical examination revealed palpable abdominal pelvic mass. Ultrasonography showed right pelvic mass arising from right adnexa measuring 15cm x 15 cm, predominantly solid with some cystic areas. The patient was suspected of having a malignant ovarian tumor and hence operated. A histopathological diagnosis revealed sclerosing stromal tumor of ovary. Sex cord-stromal tumors account for approximately 8% of all ovarian tumor and prevalence of sclerosing stromal tumor of ovary is 1.5% to 6% .This rare neoplasm is not always possible to predict pre-operatively on the basis of clinical and radiological findings. Histologically, it is characterized by several unique features including pseudolobulation, sclerosis, and prominent vascularity. Sclerosing stromal tumor is rare but possibility of this tumor should be considered in young patients with ovarian mass having the characteristic histopathological morphology.Birat Journal of Health Sciences 2016 1(1): 83-86

scholarly journals Ovarian fibrothecoma: An uncommon cause of a large pelvic mass

2016 ◽  
Author(s):  
Nikita Kumari ◽  
Reenu Kanwar ◽  
Bindu Bajaj ◽  
Garima Kapoor
Keyword(s):  
Ovarian Tumor ◽  
Histopathological Examination ◽  
Wide Spectrum ◽  
Pelvic Mass ◽  
Mass Effect ◽  
Left Ovary ◽  
Cystic Tumor ◽  
Normal Limits ◽  
Malignant Ovarian Tumor ◽  
Cystic Changes

Introduction: Ovarian fibrothecomas represent an ovarian stromal neoplasm developing in a wide spectrum of clinical settings. These tumors have been described as rare ovarian neoplasm, accounting for about 4% of all ovarian tumors. We report a case whose clinical presentation was highly deceptive and was clinically and radiologically diagnosed as malignant ovarian tumor. Ascitic fluid cytology revealed absence of malignant cells. On histopathological examination, it was diagnosed as benign fibrothecoma with cystic changes. Postoperative follow-up for about six months was uneventful. Case: A 45 year old female presented to the gynae emergency with large abdominal lump of 20 weeks size with acute pain abdomen. She was admitted for initial management and thorough evaluation. Hematological and biochemical parameters were within normal limits. USG revealed a large multilocular, predominantly cystic lesion 20.9x9.6x11.4 cm in pelvis. CECT revealed ovarian cystadencarcinoma left ovary with locoregional mass effect, mild ascites and suspicious metastasis to internal iliac lymph nodes. Radiological and preoperative clinical diagnosis was malignant ovarian tumor. Panhysterectomy and omentectomy was performed. On gross examination, a well encapsulated, multinodular cystic tumor of left ovary about 17x14x7 cm was identified. Cut surface was mostly solid with few cystic areas. Uterus, cervix, right ovary and both tubes were unremarkable. On microscopic examination, multiple sections showed spindle shaped cells in storiform and palisading pattern. No mitotic activity was identified. On special staining, it was positive for vimentin, which is a characteristic feature of ovarian fibrothecoma. Conclusion: The accurate preoperative diagnosis of ovarian fibrothecoma with cystic changes could have prevented the extensive surgical intervention such as bilateral salpingo- oopherectomy with hysterectomy.

scholarly journals Ovarian Sex Cord–Stromal Tumors: Reflections on a 40-Year Experience With a Fascinating Group of Tumors, Including Comments on the Seminal Observations of Robert E. Scully, MD

2018 ◽  
Vol 142 (12) ◽  
pp. 1459-1484 ◽  
Author(s):  
Robert H. Young
Keyword(s):  
Granulosa Cell ◽  
Wide Spectrum ◽  
Granulosa Cell Tumor ◽  
Cell Tumor ◽  
Stromal Tumor ◽  
Entire Family ◽  
Stromal Tumors ◽  
Juvenile Granulosa Cell Tumor ◽  
Sclerosing Stromal Tumor ◽  
Sex Cord Stromal Tumors

Context.— This year being the 60th anniversary of the publication of the excellent book Endocrine Pathology of the Ovary by John McLean Morris, MD, and Robert E. Scully, MD, the writer reflects on that work and in particular the remarkable contributions of its second author to our knowledge in this area. Objective.— To review ovarian sex cord–stromal tumors. Data Sources.— Literature and personal experience. Conclusions.— The essay begins with remarks on the oftentimes straightforward stromal tumors of the ovary because the commonest of them, the fibroma, dominates from the viewpoint of case numbers. Then, the sclerosing stromal tumor and the peculiar so-called luteinized thecomas of the type associated with sclerosing peritonitis are discussed in greater detail and their wide spectrum is illustrated. Brief mention is made of 2 rare neoplasms: the ovarian myxoma and signet-ring stromal tumor. Discussion then turns to the more recently recognized intriguing tumor tentatively designated microcystic stromal tumor and the commonest malignant tumor in this entire family, the so-called adult granulosa cell tumor, which despite its name may occasionally be seen in young individuals. The second variant of granulosa cell tumor—that which usually, but not always, occurs in the young—the so-called juvenile granulosa cell tumor, is then discussed. In the section of Sertoli-Leydig cell tumors, particular attention is focused on unusual tumors with heterologous elements and the remarkable so-called retiform tumors, which have a predilection for the young, often have distinctive gross features, and exhibit slitlike spaces and papillae. The essay concludes with consideration of the sex cord tumor with annular tubules.

scholarly journals Extra Gastrointestinal Stromal Tumor Pada Ovarium, Kasus Jarang

2020 ◽  
Vol 4 (2) ◽  
pp. 173-182
Author(s):  
Nana Liana ◽  
RZ Nizar ◽  
Aswiyanti Asri ◽  
Hera Novianti ◽  
Andi Friadi
Keyword(s):  
Differential Diagnosis ◽  
Gastrointestinal Stromal Tumor ◽  
Ovarian Tumor ◽  
Stromal Tumor ◽  
Ovarian Malignancy ◽  
Tumor Surgery ◽  
Pathological Anatomy ◽  
History Of ◽  
Gynecological Disorder ◽  
Rule Out

Objective : This article objective is to describe a woman with extra gastrointestinal stromal tumor (extra GIST) in ovary; Method : A case report and literature review; The author reports a woman 54 years old with complaints of swelling in the abdomen. Tumors suspected originate from ovary with an extension to abdominal wall. The patient had history of previous ovarian tumor surgery with pathological anatomy diagnosis was thecoma. Working diagnosis of the patient was residif ovarian malignancy and then suboptimal debulking was performed. Microscopically, ovarian tumors appear cellular and diffuse, partially arranged fascicles. Cells with rounded-spindle nuclei, mitosis ≥ 4 per 10 HPF. The conclusion was malignant thecoma which metastasizes to peritoneum and omentum. Differential diagnosis were GIST and leiomyosarcoma. Immunohistochemistry examination was performed with  Calretinin and CD117 to rule out the differential diagnosis. Calretinin were negative  and CD117 were strongly positively smeared. Based on the morphology and positive CD117 results, diagnosis was extra GIST of ovary.; Conclusion: Extra GIST in the ovary is an unusual location so that it can be misdiagnosed as a gynecological disorder. The differential diagnosis at this location is quite limited including thecoma, fibrothecoma and leiomyosarcoma.Keywords: extra gastrointestinal stromal tumor, ovary, thecoma

scholarly journals Degenerated fibroid - a diagnostic challenge

2016 ◽  
Vol 6 (1) ◽  
pp. 292
Author(s):  
Sonal Bhuyar ◽  
Bhavana Sontakke ◽  
Pooja Mukund Rajbhara
Keyword(s):  
Ovarian Tumor ◽  
Unusual Case ◽  
Uterine Fibroids ◽  
Total Abdominal Hysterectomy ◽  
Large Mass ◽  
Abdominal Hysterectomy ◽  
Diagnostic Challenge ◽  
Malignant Ovarian Tumor ◽  
History Of ◽  
Leiomyoma Of The Uterus

Leiomyoma of the uterus is the most common type of tumor affecting the female pelvis and arises from uterine smooth muscle. The size of leiomyoma varies from microscopic to giant; giant myoma is exceedingly rare. We report an unusual case of a large, cystic, uterine leiomyoma mimicking a primary malignant ovarian tumor on sonography and CT. A 39 year old infertile nulliparous woman presented with a history of lump in abdomen since 2 years and 6 months of amenorrhea. Sonography and CT examination showed a large mass that filled the abdomen. A preoperative diagnosis of a primary malignant ovarian tumor was made. The patient underwent laparotomy with total abdominal hysterectomy preserving tubes and ovaries. The histology revealed a leiomyoma with extensive hyaline degeneration. The current established management of uterine fibroids may include expectant, surgical, or medical management or uterine artery embolization or a combination of these treatments. A surgical approach is preferred for management of giant leiomyomas. Leiomyomas should be considered in the differential diagnosis of a multilocular and predominantly cystic adnexal mass.

P08.11: The great imitator: gastrointestinal stromal tumor mimicking malignant ovarian tumor

2005 ◽  
Vol 26 (4) ◽  
pp. 428-428
Author(s):  
L. Hereter ◽  
M. A. Pascual ◽  
F. Tresserra ◽  
M. Fernandez-Cid ◽  
R. Fabregas
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Ovarian Tumor ◽  
Stromal Tumor ◽  
Malignant Ovarian Tumor

scholarly journals Extra Gastrointestinal Stromal Tumor Pada Ovarium, Kasus Jarang

2020 ◽  
Vol 4 (2) ◽  
pp. 204-213
Author(s):  
Nana Liana ◽  
RZ Nizar ◽  
Aswiyanti Asri ◽  
Hera Novianti ◽  
Andi Friadi
Keyword(s):  
Differential Diagnosis ◽  
Gastrointestinal Stromal Tumor ◽  
Ovarian Tumor ◽  
Stromal Tumor ◽  
Ovarian Malignancy ◽  
Tumor Surgery ◽  
Pathological Anatomy ◽  
History Of ◽  
Gynecological Disorder ◽  
Rule Out

Objective : This article objective is to describe a woman with extra gastrointestinal stromal tumor (extra GIST) in ovary; Method : A case report and literature review; The author reports a woman 54 years old with complaints of swelling in the abdomen. Tumors suspected originate from ovary with an extension to abdominal wall. The patient had history of previous ovarian tumor surgery with pathological anatomy diagnosis was thecoma. Working diagnosis of the patient was residif ovarian malignancy and then suboptimal debulking was performed. Microscopically, ovarian tumors appear cellular and diffuse, partially arranged fascicles. Cells with rounded-spindle nuclei, mitosis ≥ 4 per 10 HPF. The conclusion was malignant thecoma which metastasizes to peritoneum and omentum. Differential diagnosis were GIST and leiomyosarcoma. Immunohistochemistry examination was performed with  Calretinin and CD117 to rule out the differential diagnosis. Calretinin were negative  and CD117 were strongly positively smeared. Based on the morphology and positive CD117 results, diagnosis was extra GIST of ovary.; Conclusion: Extra GIST in the ovary is an unusual location so that it can be misdiagnosed as a gynecological disorder. The differential diagnosis at this location is quite limited including thecoma, fibrothecoma and leiomyosarcoma.Keywords: extra gastrointestinal stromal tumor, ovary, thecoma

scholarly journals A Case Report of an Abdominal Wall Endometrioma

2021 ◽  
Vol 11 (11) ◽  
pp. 261-264
Author(s):  
Saima Najam ◽  
Messaoud Bounnah
Keyword(s):  
Abdominal Pain ◽  
Abdominal Wall ◽  
Abdominal Mass ◽  
Young Patients ◽  
Surgical Removal ◽  
Histopathological Diagnosis ◽  
Normal Delivery ◽  
Uterine Surgery ◽  
History Of ◽  
The Right

Abdominal wall endometrioma (AWE) is one of the rarest forms of the endometriosis, and usually found in the young patients, average age is 35years. The most common triad of the symptoms is, abdominal mass at or near the scar, cyclical pain and history of previous caesarean or any other gynecological surgery. Exact pathogenesis is unknown as average time of its presentation in the patients is highly variable from 3 months till 2 decades. It can be suspected on ultrasonography and CT scan and MRI are the modalities used to assess and stage the lesion prior to the surgery. Histopathological diagnosis is confirmatory. We are reporting 30 years old, Para 2, with history of first caesarean section 6 years ago followed by the normal delivery. She presented with the history of cyclical abdominal pain with the feeling of abdominal lump from last 3 months. On examination a slightly tender 5*4 cm extra abdominal mass was palpable above the right half of the previous transverse scar of the caesarean. After evaluation endometriosis was suspected and the patient opted for the surgical resection of the mass. The mass was removed in collaboration with the surgeons and the histopathology confirmed the diagnosis of the AWE. Conclusion: AWE is a dynamic yet incompletely known entity as a result of increasing number of the caesarean and gynecological procedures. It should be kept in the differential diagnosis of the patients coming with the cyclical abdominal pain and abdominal lump with the history of previous uterine surgery. Ultrasound and MRI are the main aiding modalities but the confirmation of the diagnosis is made only after histopathology. The surgical removal of the mass with negative margins represents the current best treatment. Key words: Abdominal wall, endometriosis, magnetic resonance imaging, ultrasonography.

scholarly journals Meigs syndrome: literature review of a case report

2020 ◽  
Vol 8 (10) ◽  
pp. 3706
Author(s):  
Camilo Levi Acuña Pinzón ◽  
Diego Hinojosa Ugarte ◽  
Aldo Edyair Jimenez Herevia ◽  
Miguel Angel Guerrero
Keyword(s):  
Pleural Effusion ◽  
Ovarian Tumor ◽  
Tumor Resection ◽  
Stromal Tumor ◽  
Ca 125 ◽  
Malignant Neoplasms ◽  
Chest Tubes ◽  
Debulking Surgery ◽  
Tumor Debulking ◽  
Sex Cord Stromal Tumors

Ovarian cancer is the presence of one or multiple tumors, which appears in one or both ovaries. These tumors are usually classified as epithelial and non-epithelial. Sex cord-stromal tumors are a group of benign and malignant neoplasms that develop from the sexual cord. Many are functional and therefore have hormonal secretions. Meigs syndrome is defined by the presence of pleural effusion and ascites in association with an ovarian tumor. We present a case of a 55 years old patient who was admitted due to a pelvic tumor, exudative pleural effusion that was difficult to manage, and ascites. A benign ovarian stromal tumor associated with elevated Ca 125 was diagnosed. After the management of the effusions, a 20x20x10 cm ovarian tumor resection was performed by laparotomy, and a transoperative report of a thecoma/fibroma type stromal tumor was received. Meigs syndrome occurs in 1% of ovarian tumors, being very rare before the third decade of life, the pathogenesis of ascites and pleural effusion could be related to the imbalance of hydrostatic forces between arterial flow and lymphovenous drainage culminating in a stromal transudate. Treatment of this syndrome should be focused on tumor debulking surgery and symptomatic treatments such as chest tubes and pleurodesis.

scholarly journals A rare case of virilizing adult granulosa cell tumor

1970 ◽  
Vol 39 (136) ◽  
pp. 351-353
Author(s):  
Kaveeta Dawaka ◽  
A Gupta ◽  
S Joshi ◽  
S Bajpai ◽  
H S Basi
Keyword(s):  
Granulosa Cell ◽  
Ovarian Tumor ◽  
Granulosa Cell Tumor ◽  
Cell Tumor ◽  
Stromal Tumors ◽  
Cystic Tumors ◽  
History Of ◽  
Disproportionate Number ◽  
Sex Cord Stromal Tumors

A twenty eight year old lady, married for two years with no issue, presented at WesternRegional Hospital Pokhara on 8th July, 1999 with a history of amenorrhea for 1½years, lump abdomen 1 year, hoarseness of voice for 1 year and signs of hirsutism forthe same duration. She was taken up for laparotomy wherein a left ovariectomy withsalpingectomy was done and a large cystic ovarian tumor was removed. Post operativeperiod was uneventful and she was advised follow up. The histopathological diagnosiswas Adult Granulosa Cell Tumor. What made this case interesting is that mostGranulosa Cell Tumors (about 3/4th) are estrogenic or feminizing, but rare examples,including a disproportionate number of large thin walled cystic tumors are androgenic.This was one of those rare virilizing tumors with classical features of infertility,amenorrhea, hoarseness of voice, clitiromegaly, and breast atrophy, but we could notestimate testosterone levels due to lack of facilities available.Key Words: Granulosa Cell Tumor, Virilizing Ovarian Tumors, Sex Cord stromal tumors.

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