scholarly journals Hospital-based Analytical Study of Anti-thyroid Peroxidase Titre Among Type-2 Diabetic Patients Suffering from Thyroid Disorders

2019 ◽  
Vol 4 (1) ◽  
pp. 660-665
Author(s):  
Rajneesh Jha ◽  
Amit Mishra ◽  
Meena Kumari Mishra ◽  
Ram Lala Mallick
Keyword(s):  
Thyroid Hormones ◽  
Blood Sugar ◽  
Venous Blood ◽  
Thyroid Peroxidase ◽  
Diabetic Patients ◽  
Thyroid Disorders ◽  
Type 2 Diabetic Patients ◽  
Sugar Levels ◽  
Type 2 Diabetic

Introduction: Thyroid hormones control growth, development and metabolic processes. Either excessive or deficient secretion of these hormones interfere with metabolism. Thyroid hormones, therefore, can alter a person's blood sugar. Relatively, thyroid peroxidise enzyme plays a key role in thyroid hormone production. The individuals who suffer from autoimmune thyroid diseases produce auto antibodies against thyroid peroxidise (called anti-TPO). Objectives: We aimed to investigate an association of anti-TPO titer among type-2 diabetic patients suffering from thyroid disorders attending the local hospital. Methodology: Based on findings of thyroid variables [such as total triiodothyronine (TT3 ), thyroxine (T4 ) and thyroid stimulated  hormone (TSH)], type-2 diabetic patients were categorized into Euthyroidism, Subclinical hypothyroidism and Hypothyroidism. In this hospital-based prospective study, venipuncture was performed to collect anti-cubital venous blood samples (n=100) from January to December, 2018. After separation of sera, estimation of certain parameters such as TT3, T4 , TSH and anti-TPO were carried out for correlative analyses. In this aspect, based on WHO guidelines, the patients who had fasting as well as postprandial blood sugar levels > 126 and 200 mg/dl were confirmed for diabetes mellitus. In addition, if these patients exhibited HbA1C levels > 10.8 %, they were enrolled into the 1 study. The patients who were hyperglycemic (with fasting as well as post-prandial blood sugar levels < 126 and 200 mg/dl) were excluded. Results: In the three groups as stated above, we observed that more a rise in level of glucose, greater were the values of TSH and anti-TPO. Conclusion Such findings emphasize and put an impact in situations of thyroid abnormality among type-2 local diabetic population.

scholarly journals Low-Glycemic-Index Sugar in Type 2 Diabetic Patients: A Randomized Controlled Study

2021 ◽  
Author(s):  
Damien Steciuk ◽  
Samia Mahmood Hafez Amir ◽  
Muzzammil Hosenally ◽  
Aroushini Goorapah
Keyword(s):  
Blood Sugar ◽  
Glycemic Index ◽  
Glucose Monitoring ◽  
Controlled Study ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Sugar Levels ◽  
Type 2 Diabetic ◽  
Low Glycemic Index

Abstract Background and Objectives: There is a need to re assess the value of low-GI food and its specific components. The effect of one of them, namely low-glycemic-index sugar, is unclear, as its impact is usually confounded when reported in the literature. This study attempts to breach this gap, shedding light on its effect in type 2 diabetic patients and evaluate if it could be considered as part of a dietary plan.Subjects and Methods: The blood sugar level of twenty (20) type 2 diabetics was monitored using a Continuous Glucose Monitoring system during two phases; firstly, an initial period of 5 days, whereby all the included patients were taking their usual dietary meals. Subjects were then randomized into two groups of equal size before embarking on a second phase; 10 subjects were instructed to eat prepared, portioned and delivered meals, the difference for the second group being that low-GI sugar was used for the preparation. Results: Compared to baseline (day 1), blood sugar dropped by 18% for the group with low-GI sugar and 13% for those who consumed sugar with a normal-GI. The variation in sugar levels was also more contained in the interventional group. A by-product of the study design shows that constant glucose monitoring could raise awareness, and may foster reduction in blood sugar levels. Portioned food was capable of reducing blood sugar levels, with elevated levels of compliance just after start. Conclusions: Even though the ultimate aim is to reduce sugar consumption by diabetic patients, the intake of a low-GI sugar seems to be less harmful than normal sugar. Compared to using normal sugar for the preparation of portioned foods, the use of a low-GI sugar is encouraged as part of a wider plan for the management of diabetic patients.

scholarly journals Low-Glycemic-Index Sugar in Type 2 Diabetic Patients: a Randomized Controlled Study

2021 ◽  
Author(s):  
Damien Steciuk ◽  
Samia Mahmood Hafez Amir ◽  
Aroushini Goorapah ◽  
Muzzammil Hosenally
Keyword(s):  
Blood Sugar ◽  
Glycemic Index ◽  
Glucose Monitoring ◽  
Controlled Study ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Sugar Levels ◽  
Type 2 Diabetic ◽  
Low Glycemic Index

Abstract Background and ObjectivesThere is a need to re assess the value of low-GI food and its specific components. The effect of one of them, namely low-glycemic-index sugar, is unclear, as its impact is usually confounded when reported in the literature. This study attempts to breach this gap, shedding light on its effect in type 2 diabetic patients and evaluate if it could be considered as part of a dietary plan.Subjects and MethodsThe blood sugar level of twenty (20) type 2 diabetics was monitored using a Continuous Glucose Monitoring system during two phases; firstly, an initial period of 5 days, whereby all the included patients were taking their usual dietary meals. Subjects were then randomized into two groups of equal size before embarking on a second phase; 10 subjects were instructed to eat prepared, portioned and delivered meals, the difference for the second group being that low-GI sugar was used for the preparation. ResultsCompared to baseline (day 1), blood sugar dropped by 18% for the group with low-GI sugar and 13% for those who consumed sugar with a normal-GI. The variation in sugar levels was also more contained in the interventional group. A by-product of the study design shows that constant glucose monitoring could raise awareness, and may foster reduction in blood sugar levels. Portioned food was capable of reducing blood sugar levels, with elevated levels of compliance just after start. ConclusionsEven though the ultimate aim is to reduce sugar consumption by diabetic patients, the intake of a low-GI sugar seems to be less harmful than normal sugar. Compared to using normal sugar for the preparation of portioned foods, the use of a low-GI sugar is encouraged as part of a wider plan for the management of diabetic patients.

scholarly journals Biochemical Study on Anti Thyroid Peroxidase in Type 2 Diabetic patients with thyroid disorders

2016 ◽  
Vol 13 (4) ◽  
pp. 753-761
Author(s):  
Baghdad Science Journal
Keyword(s):  
Type 2 Diabetes ◽  
Biochemical Study ◽  
Study Groups ◽  
Enzyme Linked Immunosorbent Assay ◽  
Thyroid Peroxidase ◽  
Diabetic Patients ◽  
Thyroid Disorders ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Type 2 diabetes mellitus (T2DM) is the most frequent endocrinal disease commonly associated with thyroid disorders .The study is conducted at the Specialized Center for Endocrinology and Diabetes in Baghdad ,during December 2014 up to October 2015.This study was done to investigate the prevalence of anti- thyroid peroxidase (Anti-TPO) antibody in patients suffered from type 2 diabetes with thyroid disorders .The study groups included a total number of 80 subjects consisting of 60 type 2 diabetic patients divided into 20 hyperthyroidism subjects (group 1) ,20 hypothyroidism subjects (group 2), 20 euthyroidism subjects (group 3) and 20 healthy controls (group 4) . The fasting blood samples were analyzed for (T3,T4,TSH) by using Vitek Immuno diagnstic Assay System (VIDAS). Enzyme Linked Immunosorbent Assay (ELISA) is used to detect anti-thyroid peroxidase (Anti-TPO) antibody .The results show that age, gender and BMI (body mass index) have significantly higher levels in the patients groups as compared to the healthy group at (p

scholarly journals Comparison of Lipid Profile in Type-2 Obese Diabetics and Obese Non-diabetic Individuals. A hospital Based Study from Western Nepal

2013 ◽  
Vol 10 (3) ◽  
pp. 44-47 ◽  
Author(s):  
Naval Kishor Yadav ◽  
C Thanpari ◽  
MK Shrewastwa ◽  
RK Mittal
Keyword(s):  
Lipid Profile ◽  
Venous Blood ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Serum Triglycerides ◽  
Control Subjects ◽  
Significant Difference ◽  
The Mean ◽  
Type 2 Diabetic

Background Type-2 diabetes mellitus is an independent risk factor for coronary artery disease and risk of coronary disease is three to four fold increased in patients with diabetes compared with non-diabetic population and 60-80% 0f type-2 diabetics are obese. Methods This study was conducted in Nepalgunj Teaching Hospital, Kohalpur, Banke, Nepal, between 1st March, 2011 and 28th February, 2012. A total of 150 samples were taken to assess the lipid profile in type-2 diabetic patients associated with obesity and 25 obese controls for their lipid profile. Venous blood samples were taken from all the subjects in the morning after fasting overnight. Exclusion criteria included pregnancy, chronic infectious disease, heart failure; renal failure and drug allergy were confirmed from the subject’s personal physician report and a detailed history. The data was analyzed using Excel 2003, R 2.8.0 Statistical Package for the Social Sciences (SPSS) for Windows Version 16.0 (SPSS Inc; Chicago, IL, USA) and the EPI Info 3.5.1 Windows Version. Results The mean ± SD age of diabetic patients with obesity was 53.76 ± 6.23 while the mean ± SD age of control was 49.61 ± 4.8. Out of 150 patients 105 (70%) were males and 45 (30%) were females. Among control subjects 16 (64%) were males and 9 (36%) were females. Obese type-2 diabetic patients when compared to obese control subjects showed statistically significant increase in the levels of serum total cholesterol (p ? 0.001), serum triglycerides (p ? 0.001), serum LDL-cholesterol (p ? 0.001) while serum HDL-cholesterol levels did not show statistically significant difference in the two group (p ? 0.05). Conclusion This study showed obese diabetic individuals have dyslipidemia and more prone to develop cardiovascular diseases. Kathmandu University Medical Journal | VOL.10 | NO. 3 | ISSUE 39 | JUL- SEP 2012 | Page 44-47 DOI: http://dx.doi.org/10.3126/kumj.v10i3.8017

scholarly journals Blood sugar control among type 2 diabetic patients who travel abroad

Medicine ◽  
2019 ◽  
Vol 98 (13) ◽  
pp. e14946 ◽  
Author(s):  
I-Wen Lin ◽  
Hao-Hsiang Chang ◽  
Yi-Hsuan Lee ◽  
Yi-Chun Wu ◽  
Chia-Wen Lu ◽  
...  
Keyword(s):  
Blood Sugar ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Travel Abroad ◽  
Type 2 Diabetic

scholarly journals A PROSPECTIVE STUDY ON PIOGLITAZONE EFFECT IN REDUCING TRIGLYCERIDE LEVEL IN TYPE-2 DIABETIC PATIENTS

2020 ◽  
pp. 74-76
Author(s):  
R. Vijayarani ◽  
Tarunika. K. M
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Patient Compliance ◽  
Triglyceride Level ◽  
Post Treatment ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Pre Treatment ◽  
Type 2 Diabetic

Type 2 diabetes mellitus is the most common form of diabetes mellitus characterized by hyperglycemia, insulin resistance, and relative insulin deficiency Dyslipidemia being common with diabetes, if we have a drug which can take care of both diabetes and Dyslipidemia, it will be more economical as well as increases the patient compliance. There are many studies on the effect of pioglitazone on triglyceride level. So this study was an attempt to find the effect of pioglitazone in diabetic patients with dyslipidemia in rural population. History taking and investigations were taken in 30 out patients visiting government sivagangai medical hospital between May 2019 and June 2019 The pre-treatment FBS mean was found to be 149.4+41.5 and the post treatment mean was found to be 98.2+27.3. Thus there is a significant reduction in fasting blood sugar level with p value less than 0.05. Serum triglycerides investigation pre treatment mean was found to be 181.5+18.2 and the post treatment mean is 160.07+21.03 .Thus there is a significant decrease of p<0.05 when pre and post treatment mean values were compared. The effect of pioglitazone on triglyceride level in type 2 diabetic patients was studied, it is evident that the Pioglitazone is both antidiabetic and antiatherogenic drug; we can conclude that the pioglitazone administration is effective to bring about significant change in the blood sugar, triglycerides. pioglitazone is a safe drug with less of side effects. , it will be more economical as well as increase patient compliance.

scholarly journals Association between Microalbuminuria and Hypertension in Type 2 Diabetic Patients

2019 ◽  
pp. 1-8
Author(s):  
Most. Zannatul Ferdous ◽  
M. A. Wahed ◽  
Zebunnesa Zeba
Keyword(s):  
Blood Pressure ◽  
Blood Sugar ◽  
Fasting Blood Sugar ◽  
Research Centre ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Group 2 ◽  
Type 2 Diabetic ◽  
Group 1

Aims: This study aimed to investigate the relationship between microalbuminuria and hypertension in type 2 diabetic patients. Study Design: It was a descriptive type of cross-sectional study. Place and Duration of Study: The study was conducted in collaboration at a diabetic clinic and Hypertension and Research Centre, Rangpur, Bangladesh from January to March 2018. Methodology: A total of 180 diabetic patients were selected purposively age ranges 30-75 years. Anthropometric as well as biochemical measurement was done. Data was collected by a semi-structured questionnaire through face to face interview and analyzed by SPSS-20. Results: Study subjects were separated into two groups. Group 1, those with normoalbuminuria (n=49) and Group 2, those having microalbuminuria (n=131). The prevalence of microalbuminuria was 72.8%. Group 2 or microalbuminuric patients showed higher blood pressure values (113.50±8.90 mm of Hg) as compared to Group 1 (101.88±9.80 mm of Hg). The results were statistically significant (P≤0.05). Further this study showed fasting blood sugar, duration of diabetes, systolic blood pressure and high level of sCreatinine were independently associated with microalbuminuria in the study subjects. The results were also statistically significant (P≤0.05). Conclusion: Our study revealed high prevalence of microalbuminuria in diabetic patients and has an optimistic association with blood pressure. This study suggests the need to screen for microalbuminuria early and the active management of modifiable risk factors in particular fasting blood sugar, sCreatinine, hypertension for intervention and prevention of further complications like end stage renal disease and cardiovascular diseases.

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