scholarly journals Isolated myeloid sarcoma

2015 ◽  
Vol 4 (3) ◽  
pp. 46-48
Author(s):  
B P Rauniyar ◽  
X Liu ◽  
J Shrestha ◽  
K R Devkota ◽  
S Poudel ◽  
...  
Keyword(s):  
Lymph Node ◽  
Case Reports ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Myeloid Sarcoma ◽  
Tumour Mass ◽  
Medical College ◽  
Node Biopsy ◽  
Immature Myeloid Cells ◽  
Prospective Trials

Myeloid Sarcoma (MS) is a tumour mass of myeloblasts or immature myeloid cells in an extra-medullary site. Isolated MS is a red disease found only seen in case reports. Here, we present the case of a 25years old man with bilateral cervical lymphadenopathy who was diagnosed as MS on the basis of lymph node biopsy and immunohistochemistry. There is no definite consensus on management of MS and needs prospective trials. DOI: http://dx.doi.org/10.3126/jcmc.v4i3.11941Journal of Chitwan Medical College 2014; 4(3):46-48 

scholarly journals Kikuchi necrotizing lymphadenopathy: a tip of the iceberg disease?

2021 ◽  
Vol 8 (9) ◽  
pp. 1602
Author(s):  
Sushil Singla ◽  
Mohitesh Kumar ◽  
Vinod Kumar Jat ◽  
Deepika Parwan
Keyword(s):  
Lymph Node ◽  
Laboratory Test ◽  
Young Patient ◽  
Healthy Individual ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Benign Condition ◽  
Node Biopsy ◽  
Necrotizing Lymphadenitis

Kikuchi-Fujimoto disease (KFD) is a rare benign condition also called histiocytic necrotizing lymphadenitis, which typically presented as fever with cervical lymphadenopathy in previously healthy individual. We presented a case of 11 year old boy with fever and cervical lymphadenopathy since 2 months. Lymph node biopsy was performed which suggested of KFD and was treated symptomatically. KFD incidence is rare but clinicians should be alert if young patient comes with fever and cervical lymphadenopathy to lower the chance of unwanted laboratory test and harmful treatment. 

Predictors of the necessity for lymph node biopsy of cervical lymphadenopathy

2015 ◽  
Vol 43 (10) ◽  
pp. 2200-2204 ◽  
Author(s):  
Tadataka Tsuji ◽  
Koichi Satoh ◽  
Hiroshi Nakano ◽  
Yoshiya Nishide ◽  
Yasuhiro Uemura ◽  
...  
Keyword(s):  
Lymph Node ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Node Biopsy

scholarly journals Case Report: Kikuchi: The great mimicker

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 520
Author(s):  
Kevin Bryan Lo ◽  
Anna Papazoglou ◽  
Lorayne Chua ◽  
Nellowe Candelario
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Disease Patient ◽  
Cervical Lymphadenopathy ◽  
Hematologic Malignancies ◽  
Lymph Node Biopsy ◽  
Benign Disease ◽  
Node Biopsy ◽  
Necrotizing Lymphadenitis ◽  
Serious Disease

Kikuchi-Fujimoto disease is a form of a benign necrotizing lymphadenitis which is most commonly misdiagnosed as tuberculosis and or lymphoma, usually more common among young adults in Asia. It is a benign disease but can mimic a lot of other disease processes spanning infectious, rheumatologic and even hematologic malignancies. Our patient presented with prolonged fever and lymphadenopathy. Initial considerations were lymphoma and a nonspecific viral infection. A CT scan showed diffuse cervical lymphadenopathy with lacrimal gland involvement. An excisional lymph node biopsy was done which revealed Kikuchi disease. Patient was given steroids with immediate response with defervescence. Kikuchi is a disease with many mimics and a complete workup is needed to exclude serious disease like malignancy.

scholarly journals Disseminated cat-scratch disease: a case report

2015 ◽  
Vol 22 (2) ◽  
pp. 229-231
Author(s):  
Faizul Islam Chowdhury ◽  
MA Kashem ◽  
Md Anwar Hossain ◽  
Imran Munadil Ahsan ◽  
Avijit Pandit ◽  
...  
Keyword(s):  
Bartonella Henselae ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Cat Scratch Disease ◽  
Gram Negative ◽  
Systemic Involvement ◽  
Medical College ◽  
Negative Bacillus ◽  
Node Biopsy ◽  
Gram Negative Bacillus

Cat-scratch disease is an infectious disease caused by Bartonella henselae, a gram-negative bacillus. The disease is usually transmitted to the human being by cat scratches. Cat-scratch disease typically presents with painful regional lymphadenopathy. Systemic involvement is unusual. A 35 years old lady, came with the complaints of fever, abdominal pain along with nausea, anorexia & difficulties of swallowing for 6 months. She has painful cervical lymphadenopathy. Histopathology of her lymph node biopsy shows features of cat-scratch disease. DOI: http://dx.doi.org/10.3329/jdmc.v22i2.21550 J Dhaka Medical College, Vol. 22, No.2, October, 2013, Page 229-231

scholarly journals Cervical-facial adenopathies in Odonto-stomatology: Study of 82 observations

2017 ◽  
Author(s):  
Boubacar Ba ◽  
Issa Konaté ◽  
Drissa Goita ◽  
Abdoulaye Kassambara ◽  
A Toure ◽  
...  
Keyword(s):  
Lymph Node ◽  
Medical Records ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
University Hospital ◽  
Tuberculous Lymphadenitis ◽  
Early Management ◽  
Node Biopsy ◽  
The University ◽  
Anatomic Region

Objective: The objective of this study is to describe the etiological profile of patients with cervical lymphadenopathy in relation to tuberculosis in our practice Odonto-stomatologique.Materials and Methods: We conducted a retrospective study over a period of four years at the University Hospital of Stomatology Odonto (CHU OS) Bamako. The successive cases of cervical lymphadenopathy of tuberculous origin confirmed by skin test (TST) to tuberculin 10 units or lymph node biopsy for histological referred. Data were collected from medical records and entered and analyzed with the software Epiinfo.fr 6.0Results: The lesions involved 82 patients including 37 men (45.1%) with a sex ratio of 1.21. The age group most represented was that of 20 and 29 years (28%). The anatomic region was privileged bilateral cervical (57.30%).Our patients underwent chest radiography in 90.20% of cases. The IDR was performed in 72% of patients and tuberculous lymphadenitis and follicular caseo was found in 8.50% of cases.Conclusion: Our study revealed a prevalence of 0.31% of cervical-facial adenopathies of which 80.50% was tuberculous. In the case of tuberculous endemic tuberculous adenopathy, an IDRT and anatomopathological examination of the lymph node biopsy should be systematic for the early management of tuberculosis

scholarly journals Kikuchi–Fujimoto Disease Associated With Mycoplasma Pneumoniae Infection

2021 ◽  
pp. 014556132110442
Author(s):  
Rui-Bin Yu ◽  
Yi-Jia Chen ◽  
Chun-Hsiang Chang ◽  
Yen-Lin Chen ◽  
Jeng-Wen Chen
Keyword(s):  
Lymph Node ◽  
Antibiotic Treatment ◽  
Mycoplasma Pneumoniae ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Asian Women ◽  
Limited Disease ◽  
Node Biopsy ◽  
Mycoplasma Pneumoniae Infection

Kikuchi–Fujimoto disease (KFD) is a self-limited disease that is more common in young Asian women. Typical presentations included fever and cervical lymphadenopathy. The etiology of KFD is unknown, and diagnosis is based mainly on lymph node biopsy. KFD has been reported to be associated with Mycoplasma pneumoniae infection. However, the role of antibiotic treatment is unclear. We reported 2 cases of KFD associated with Mycoplasma pneumoniae infection and were successfully treated with a macrolide.

Thalidomide: An Active Agent in AILT Lymphoma

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 4960-4960
Author(s):  
Ross Henderson ◽  
David Simpson ◽  
Merit Hanna ◽  
Sanjeev Chunilal
Keyword(s):  
Bone Marrow ◽  
Lymph Node ◽  
Bone Marrow Biopsy ◽  
Poor Prognosis ◽  
Case Reports ◽  
Lymph Node Biopsy ◽  
Red Cell ◽  
Red Cell Aplasia ◽  
Node Biopsy ◽  
Systemic Symptoms

Abstract Angioimmunobalstic T cell lymphoma (AILT) is a relatively rare subtype of lymphoma, accounting for approximately 1 – 2% of all cases of NHL. The pathogenesis is thought due to clonal expansion of follicular T-helper cells which subvert normal germinal centre function. It is characterised by systemic disease and significant immune dysregulation with frequent atypical infections and autoimmune disease. It has a poor prognosis with a median survival of less than 3 years using CHOP or CHOP-like regimens. Dose intensification, or anthracycline use, appears to be ineffective. Thalidomide is an immunomodulatory agent with isolated case reports of activity in this disease. We report 3 cases of AILT where thalidomide was effective at inducing or providing a sustained remission. Case 1 was an 86 year old woman who presented with systemic symptoms, widespread lymphadenopathy and a polyclonal increase in immunoglobulins. AILT was diagnosed from both lymph node biopsy and bone marrow biopsy. Symptoms improved only temporarily with prednisone. She commenced thalidomide at 200mg daily with improvement in symptoms and resolution of lymphadenopathy and after 2 months the dose was reduced to 100mg daily. She continued the thalidomide at the same dose and remained in remission until her death from unrelated causes 4 years later Case 2 was a 72 year old man who initially presented with autoimmune haemolytic anaemia and red cell aplasia which was unresponsive to steroids, intravenous immunoglobulins (IVIG), cyclosporine and splenectomy. He then developed cervical and axillary lymphadenopathy, biopsy of which showed AILT. Bone marrow examination showed no evidence of AILT. He commenced thalidomide at 150mg daily with resolution of the haemolysis and red cell aplasia within 12 days and reduction in all lymphadenopathy. He remains in remission 3 months after commencing thalidomide and is currently on 100mg daily. Case 3 was a 57 year old woman presented with ITP with platelets < 10, systemic symptoms, widespread lymphadenopathy and hepatosplenomegally. AILT was diagnosed from lymph node biopsy and bone marrow biopsy. She commenced on prednisone and IVIG for the ITP, then proceeded to CHOP chemotherapy. Her first cycle was complicated by Pneumocystis jirovecii infection. Following the chemotherapy, her systemic symptoms subsided and the lymphadenopathy and organomegaly resolved. She commenced thalidomide at 100mg daily and has remained in remission 2 months later. There are now several case reports in the literature indicating that thalidomide is effective in AILT which is reflected by the cases reported here. Given the poor prognosis of AILT using conventional chemotherapeutic regimens, such as CHOP, prospective clinical trials using thalidomide, or the newer derivatives such as lenalidomide, are warranted.

scholarly journals A Rare Case of Kikuchi Fujimoto’s Disease with Subsequent Development of Systemic Lupus Erythematosus

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Yu Zuo ◽  
Michelle Foshat ◽  
You-wen Qian ◽  
Brent Kelly ◽  
Brock Harper ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lymph Node ◽  
Lupus Erythematosus ◽  
Case Reports ◽  
Subsequent Development ◽  
Sporadic Case ◽  
Lymph Node Biopsy ◽  
Systemic Lupus ◽  
Node Biopsy ◽  
Short Course

Kikuchi Fujimoto’s disease (KFD) is a rare, immune-mediated, self-limiting disorder with unique histopathological features. KFD is usually seen in young Asian females; however, cases have been reported throughout the world and in all ethnicities. It has been recognized that there is a rare association between Systemic Lupus Erythematosus (SLE) and KFD via sporadic case reports. The exact pathophysiological relationship between these two diseases is still unclear. We report a case of a young Asian female who presented with persistent fever and lymphadenopathy and was diagnosed with Kikuchi Fujimoto’s disease based on lymph node biopsy; although an SLE workup was done, she did not meet the American Rheumatology Association (ARA) diagnostic criteria for lupus, and the lymph node biopsy did not show features of SLE. She improved clinically with a short course of steroid therapy. Two months later, the patient presented with central facial rash and arthralgia. SLE workup was repeated, a skin biopsy was done, and the results at this time supported a diagnosis of SLE.

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