scholarly journals Prevalence of Metabolic Syndrome and Its Components in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study at a Tertiary Care Teaching Hospital

2019 ◽  
Vol 9 (2) ◽  
pp. 24-29
Author(s):  
Santosh Timalsina ◽  
Pratima Pandit

Introduction: The metabolic syndrome (MetS) is a cluster of risk fac­tors that is responsible for most of the excess cardiovascular morbidity amongst patients with Type 2 Diabetes Mellitus (T2DM). Presence of MetS in T2DM markedly increases the risk for coronary heart disease, stroke and premature deaths. This study was undertaken to find the prevalence of MetS and its individual components among patients with T2DM visiting Chitwan Medical College and Teaching Hospital, Bharat­pur, Nepal. Methods: A laboratory-based descriptive cross sectional study carried out at CMC-TH between January and August, 2017. Data obtained in­cluded anthropometric indices, blood pressure and fasting serum lipid profile. National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria were used for diagnosis of MetS. Data was ana­lyzed using SPSS version 20. Results: The overall prevalence of MetS among 150 T2DM patients (Mean age= 53.70±10.83 years, Male:Female=84:66) was 60%. The prev­alence was higher in females compared to males (75.75% vs.47.62%, P<0.001). High blood pressure was the commonest MetS component. Following that, decreased HDL-c was the predominant component in females whereas raised triglyceride in the males. SBP/DBP, BMI and waist circumference were significantly associated with MetS. Conclusion: The prevalence of MetS is high in diabetic patients, particu­larly in females and middle age group adults, with high blood pressure and hypertriglyceridemia as the commonest abnormalities. As MetS adds to the cardiovascular risk to the already at-risk diabetic popula­tion, timely identification and appropriate intervention is of utmost im­portance in reduction of disease burden in T2DM patients.

1970 ◽  
Vol 28 (4) ◽  
Author(s):  
Tariku Shimels ◽  
Melesse Abebaw ◽  
Arebu I. Bilal ◽  
Tariku Tesfaye

BACKGROUND: The prevalence of T2DM in Ethiopia is on the rise according to certain studies. Appropriate management approaches are required to achieve desired goals of therapy in the clinical setup. This study was conducted to assess the treatment pattern and the factors associated with BP and FPG control among patients with T2DM in Federal Police Referral Hospital.METHOD: An institution based cross sectional study was conducted from 15th October 2016 to 15th January 2017. A Systematic random sampling technique was employed in selecting the study participants. Data was collected using semi-structured interview and visiting medication records. SPSS version 20 was used for data analysis.RESULTS: Out of a total of 414 participants who fulfilled the inclusion criteria, 361 were successfully interviewed and considered for further analysis. Target BP level was achieved in 206(57.1%) of the patients, whereas the proportion of hypertensive diabetics who attained the recommended BP target was 19.4% (n=40). Of the 361 participants who were checked about their current FPG level, only 142(39.3%) were found to be <130mg/dl. However, 87(24.1%) participants were found to control both BP and FPG levels. Gender, military status, comorbidity, type oftherapy and dietary adherence showed a statistically significant association with outcome variables.CONCLUSION: The proportion of participants with T2DM who achieved target BP, FPG or both was suboptimal. A comprehensiveapproach that involves targeted education on self-management strategies, individualized treatment plans, and continuous evaluation of treatment outcomes should be practiced.KEYWORDS: Blood pressure, Cross sectional study, Ethiopia, Fasting plasma glucose control, type 2 diabetes mellitus


2019 ◽  
Vol 18 (2) ◽  
pp. 36-41
Author(s):  
Dipesh Shakya ◽  
Vijay KC

Introduction: Diabetes mellitus is associated with various metabolic disorders, which leads to the progression of the disease and its complications. The aim of the study is to find out prevalence of metabolic syndrome and its association with the components and demographic variables. Methods: This cross-sectional study was conducted among diabetes mellitus patients at a Tertiary level teaching hospital over a period of one year (April 2015 to March 2016). The study involved the use of a questionnaire to obtain information on diabetes by performing anthropometric measurements and corroborating it with respective blood samples collected for the measurement of biochemical parameters, fasting blood glucose and lipid profile. Metabolic syndrome was defined according to the current guidelines, revised in 2005 by the National Heart, Lung and Blood Institute and the American Heart Association. Statistical Package for the Social Sciences Version 20 was used as a tool for statistical analysis. Results: This cross-sectional study involved 200 type 2 diabetes mellitus patients. The prevalence of metabolic syndrome was 71% in the studied Nepalese population. Central obesity (77.5%) and hypertension (76.8%) were the commonest risk factors. It was followed by dyslipidemia among which 65.5% had high triglyceride level and 50.7% had low level of high density lipoprotein cholesterol. Higher prevalence of metabolic syndrome was seen in male patients with type 2 diabetes which accounted for 84 (73.3%). Three components of metabolic syndrome were seen among 70 (35%) and five components among 29 (14.5%) patients. Among the patients who were studied, the age group 45 to 54, 55 to 64 and 65 to 74 years had 14 (20%), 20 (28.6%) and 19 (27.1%) of more than three components of metabolic syndrome respectively. Conclusions: The prevalence of metabolic syndrome was 71% among the patients with type 2 diabetes, where high prevalence was seen among males. In our study central obesity and hypertension along with increasing age were the most common component causing metabolic syndrome.  


2019 ◽  
Author(s):  
Lonestar Lazarus Gonde ◽  
Moses John Chimbari ◽  
Tawanda Manyangadze

AbstractBackgroundHypertension (HTN) and type 2 diabetes mellitus (T2DM) are reported to be on the increase in developing countries. In this study we investigated the epidemiology of the prevalence of HTN and T2DM and its correlates in a high density area. We carried out this study to assess the magnitude of the prevalence of HTN and T2DM so that we can query the drivers that are causing an increase conditions in these conditions.MethodsWe conducted a cross-sectional study in Hatcliffe, a high density area (HDA) in Harare. We interviewed, bled, took anthropometric and measured blood pressure of 381 participants. We investigated HbA1c, blood pressure, BMI and prevalence of prehypertension, prediabetes, co-existence of HTN and T2DM. A geospatial analysis was carried out to ascertain distribution patterns of HTN and T2DM in Hatcliffe.ResultsThe prevalence for prehypertension and prediabetes is higher than it is for full blown conditions of the HTN and T2DM. The prevalence of prehypertension was 35.4% and prediabetes was 29%. The prevalence of HTN in this study was 14.4% whilst that of T2DM was 3.93%. Out of the 55 participants that had developed HTN five had developed T2DM. There was no significant difference in the HTN and T2DM clusters.ConclusionsThe prevalence for prehypertension and prediabetes is higher than it is for full blown conditions of the HTN and T2DM. This indicates the importance of having a strategy for reducing the number of prediabetes and prehypertensive cases so that cases of full blown T2DM and HTN remain low.


2021 ◽  
Author(s):  
Oliver Okoth Achila ◽  
Millen Ghebretinsae ◽  
Abraham Kidane ◽  
Michael Simon ◽  
Shewit Makonen ◽  
...  

Abstract Background: Type 2 Diabetes Mellitus (T2DM) is an escalating problem worldwide and is frequently associated with Metabolic Syndrome (MetSyn) which, in turn, is causally associated with heightened cardiometabolic risk. Therefore, investigating the magnitude of MetSyn in T2DM patients is critical for cardiovascular disease prevention or management of specific comorbidities. Methods: This cross-sectional study was conducted among 309 previously diagnosed T2DM patients. Data on specific clinical chemistry and anthropomorphic parameters was collected. MetSyn was defined according to the IDF harmonized criteria. Pearson Chi-Square test (ꭓ2)/or Fisher’s exact test in the CROSSTAB procedure was used to evaluate the relationship between specific variables. Logistic regression models were constructed to assess risk factors associated with MetSyn. Results: According to the data, 58.1% of the patients had MetSyn. The frequency of MetSyn in females was significantly higher compared to that of males (67.8 vs 49.7%). Among individuals with MetSyn, 54.4% had hypertension; 57.9% had abnormal waist circumference; 75.4% had elevated LDL-C (≥100 mg/dL), 72.8% had raised TG (>150 mg/dl) and 61.0% had reduced HDL-C (males: ≤40 mg/dL and females: ≤50 mg/dL in females). Separately, our study demonstrates that number of MetSyn components is associated with higher averages in multiple traditional (BMI, TG, TC, WHtR, WHR, WC, HC) and non-traditional (TG/HDL-C, TC/HDL-C and LDL/HDL) CVD risk indicators. In the fitted multivariable logistic regression model, the following factors were associated with the presence of MetSyn: age (aOR=1.02, 95%CI=1.00–1.05, p=0.040); LDL-C>100 mg/dL (aOR=3.56, 95%CI=1.52–8.54, p=0.003); Non-HDL-C (aOR=1.02, 95%CI=1.02–1.03, p=0.001); BMI (aOR=1.23, 95%CI = 1.13–1.32, p=0.001). Absence of insulin injection was associated with reduced presence of MetSyn (aOR=0.37,95% CI=0.19–0.70, p=0.002). Conclusion: A comparatively high prevalence of the MetSyn was found. Therefore, there is an urgent need for improvements in the management and prevention of multiple CVD risk indicators. This will require evidence-based optimization of pharmacological and non-pharmacological interventions.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2393-PUB
Author(s):  
KENICHIRO TAKAHASHI ◽  
MINORI SHINODA ◽  
RIKA SAKAMOTO ◽  
JUN SUZUKI ◽  
TADASHI YAMAKAWA ◽  
...  

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