scholarly journals Insights into Cardiovascular Disease Risk Based on Platelet Indices and Lipid Ratios in Reference to Glycemic Control and Duration of Diabetes

2020 ◽  
Vol 9 (2) ◽  
pp. 55-60
Author(s):  
Prabodh Risal ◽  
Rajendra Dev Bhatt ◽  
Nikita Sakhakarmi ◽  
Saroj Thapa ◽  
Surendra Koju
Keyword(s):  
Cardiovascular Disease ◽  
Glycemic Control ◽  
Blood Lipids ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Control Group ◽  
Diabetic Patients ◽  
Platelet Indices ◽  
Duration Of Diabetes ◽  
Lipid Ratios

Background: Diabetic patients are at the risk of untimely atherosclerotic cardiovascular disease. The level of blood lipids, their ratios, glycosylated hemoglobin, and platelet indices are potential markers for the assessment of cardiovascular disease risk in diabetic patients. This study aims to insights into cardiovascular disease risk among diabetic patients in reference to glycemic control and duration of diabetes on the basis of lipid ratios and platelet indices by comparing with healthy controls. Materials and Methods: A case control study was carried out among the patients, diagnosed as type 2 diabetes mellitus at Dhulikhel hospital-Kathmandu University hospital. Socio-demographic questionnaire, anthropometric measurements, and biochemical tests was performed. Descriptive analysis and independent T-test for the testing relationship between categorical variables along with correlation was done. Results: Nearly one-third of diabetic patients were under poor glycemic control with high risk of cardiovascular diseases on the basis of blood lipid ratios and platelet indices. Cardiac risk ratio, Atherogenic Index of Plasma, and Atherogenic Coefficient was found to be significantly high in diabetic compared to the control group (5.22±1.54 vs. 3.71±0.99, p <0.05), (0.33±0.18 vs. 0.22±0.14, p <0.05), (4.22±1.54 vs. 2.71±0.99, p <0.05) respectively. Similarly Mean Platelet Volume was also significantly higher in diabetic compared to the control group (10.16±1.43 vs. 9.06±0.81, p <0.05). Conclusion: Poor glycemic control seems riskier than prolonged diabetes on the basis of blood lipids, their ratios and platelet indices.

scholarly journals Association of Xanthelasma palpebrarum (XP) with cardiovascular disease (CVD) risk factors

2020 ◽  
Vol 5 (4) ◽  
pp. 324-329
Author(s):  
AHM Khairul Imam Suman ◽  
Khadija Begum ◽  
Kaniz Rahman ◽  
Abu Mohammed Talukder ◽  
SM Matiur Rahman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Cardiovascular Disease Risk Factors ◽  
Total Serum ◽  
Control Group ◽  
Total Serum Cholesterol ◽  
Xanthelasma Palpebrarum ◽  
Chi Square Analysis

Xanthelasma palpebrarum (XP) is the most common cutaneous xanthoma occurs over or surrounding the eyelids in yellowish color and various shapes. The objective of this study was to describe the status of cardiovascular disease risk factors in XP patients and determine their association with XP. A case-control study was conducted among 81 cases (have XP) and 81 controls (no XP) among patients attended for cardiac check-up between January 2019 to July 2019 at Ad-Din Women's Medical College Hospital, Dhaka, Bangladesh. Among 162 subjects were interviewed in our study, majority were female (62.3%). XP were found more prevalent among female and several cardiac risk factors were significantly associated with XP. The chi-square analysis indicates gender (p=0.035), BMI (p=0.01), Angina history (p=0.008), and serum LDL (p=0.024) were significantly associated with presence of XP. A higher percentage of patients with high total serum cholesterol, TG levels, and LDL was observed in patients with XP in compared to control group. Our study reveals an increased presence of cardiovascular disease risk factors among patients with xanthelasma. Moreover, a statistically significant association of gender, BMI, angina history, and serum LDL with XP were observed. Asian J. Med. Biol. Res. June 2019, 5(4): 324-329

scholarly journals Cardiovascular diseases risk factors among adult diabetic patients in eastern Ethiopia

2019 ◽  
Vol 8 ◽  
pp. 204800401987498 ◽  
Author(s):  
Tekabe Abdosh ◽  
Fitsum Weldegebreal ◽  
Zelalem Teklemariam ◽  
Habtamu Mitiku
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Blood Glucose ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Density Lipoprotein ◽  
Cardiovascular Disease Risk Factors ◽  
Diabetic Patients ◽  
Eastern Ethiopia ◽  
Study Participants

Objective The aim of this study was to determine the magnitude of cardiovascular disease risk factors among adult diabetic patients at Hiwot Fana Specialized University Hospital and Jugal Hospital, eastern Ethiopia. Methods An institutional based cross sectional study was conducted on a total of 416 study participants (age ≥18 years) from February to March 2017. Data were collected using: structured questionnaires, measurements of weight, height, and blood pressure, and laboratory examination of blood lipids (total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein cholesterol) and fasting blood glucose. Data were analyzed using SPSS version 16.0 software packages. The association of cardiovascular disease risk factors with diabetes type, age, and sex was assessed by chi-square test. Result The mean age of study participants was 52 years and 44% were male. Dyslipidemia (90.6%), physical inactivity (76%), and hypertension (62.7%) were the most common cardiovascular disease risks factors identified among diabetic patients. It was also observed that 68.5% of the study participants had uncontrolled blood glucose level. Hypertension was significant in patients over 65 compared to those ≤65 years of age (p < 0.023). Females were considered to be significantly physically inactive compared to males (p < 0.001). Conclusion Dyslipidemia is the most common risk factor of CVD in individuals with Types 1 and 2 diabetes mellitus. Identification and treatment of lipid abnormalities is very important. Controlling hypertension among older patients and lifestyle modification among female diabetic patients are also recommended.

Bariatric Surgery Reduces Cardiovascular Disease Risk in Diabetic Patients

2018 ◽  
Vol 227 (4) ◽  
pp. S14-S15
Author(s):  
Camila Ortiz Gomez ◽  
David Gutierrez Blanco ◽  
David Romero Funes ◽  
Ramarao Ganga ◽  
Emanuele Lo Menzo ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Bariatric Surgery ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Diabetic Patients
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