scholarly journals Pseudomyxoma peritonei: unusual origin from teratoma associated mucinous cystadenoma of ovary

2021 ◽  
Vol 5 (1) ◽  
pp. 76-79
Author(s):  
Manju Pandey ◽  
Binuma Shrestha ◽  
Bijay Chandra Acharya ◽  
Suraj Upreti
Keyword(s):  
Abdominal Pain ◽  
Pseudomyxoma Peritonei ◽  
Mature Teratoma ◽  
Mucinous Cystadenoma ◽  
Clinical Syndrome ◽  
Abdominal Distention ◽  
Mucinous Tumor ◽  
Ovarian Involvement ◽  
Unusual Origin

Pseudomyxoma peritonei is an extremely rare clinical syndrome with incidence of approximately two per 10000 laparotomies. Approximately 44% of women with PMP have ovarian mucinous tumor. It is generally accepted that the ovarian involvement is secondary; PMP is nearly always gastrointestinal origin, usually from mucinous adenoma of the appendix1. Exception to this, we report a 35 years lady who presented with the complaint of abdominal pain and abdominal distention for two months, clinically and radiologically gross mucinous ascites with large abdominopelvic mass was evident. Final histopathology was reported as mucinous cystadenoma, with mature teratoma components, appendix was normal. 

scholarly journals Should the appendix always be removed during surgery for mucinous ovarian tumors?

2018 ◽  
Vol 7 (2) ◽  
pp. 677
Author(s):  
Bijal M. Patel ◽  
Ava D. Desai ◽  
Shilpa M. Patel ◽  
Meeta H. Mankad ◽  
Pariseema S. Dave ◽  
...  
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Mucinous Cystadenoma ◽  
Ovarian Tumors ◽  
Mucinous Tumor ◽  
Inclusion Criteria ◽  
Single Institution ◽  
Normal Appendix ◽  
History Of ◽  
Study Population ◽  
Mucinous Ovarian Tumors

Background: Appendectomy is performed in all mucinous ovarian tumors (MOT) identified intraoperatively to ensure microscopic metastases from appendix are not missed. Several recent studies suggested that appendectomy should only be performed in cases with a grossly abnormal appendix or with evidence of pseudomyxoma peritonei. Our study aimed to determine the frequency of malignancy in a grossly normal appendix in women undergoing surgery for borderline or malignant MOT.Methods: In a single institution retrospective study, women undergoing surgery for MOT from January 1, 2008 to June 30, 2016 were included. Women with benign MOT, those with a history of either prior appendicectomy or prior gastrointestinal (GI) malignancy were excluded.Results: Of 266 women identified with MOT, 153 with borderline and malignant MOT were included in the study after application of inclusion criteria. The study population comprised of 29 (18.95%) borderline and 124 (81.05%) malignant MOT. Among the borderline MOT, 13/29 had undergone appendectomy. Five (38.46%) had grossly abnormal appendices of whom 1 had mucinous cystadenoma, 3 had borderline mucinous tumor and 1 had mucinous cystadenocarcinoma of the appendix. Histology was normal in all 8 (61.54%) grossly normal appendices. Among the malignant MOT, 80/124 (64.52%) underwent appendicectomy. Nineteen (23.46%) had grossly abnormal appendices and histology was suggestive of adenocarcinoma of appendix. Histology was normal in all 62 (76.54%) macroscopically normal appendices.Conclusions: Present results suggest that appendectomy be performed only for those appendices that are grossly abnormal or associated with pseudomyxoma peritonei at surgery for MOT

scholarly journals A case of Pseudomyxoma Peritonei of an unexpected origin

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Marie Csanyi-Bastien ◽  
France Blanchard ◽  
Aude Lamy ◽  
Jean-Christophe Sabourin
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Ovarian Tumor ◽  
Histological Analysis ◽  
Mucinous Cystadenoma ◽  
Ovarian Teratoma ◽  
Mucinous Tumor ◽  
Case Presentation ◽  
Mucinous Neoplasm ◽  
Ovarian Lesion

Abstract Background Pseudomyxoma peritonei (PMP) is a complex and partially understood disease defined by mucin deposits in the peritoneal cavity, mostly of appendiceal origin caused by the rupture of a mucocele often containing Low or High grade Appendiceal Mucinous Neoplasm (LAMN/HAMN). Other origins include primitive ovarian mucinous cystadenoma or cystadenocarcinoma almost always with an associated teratoma, but to our knowledge no case of ovarian teratomatous appendiceal-like mucocele with LAMN has been reported as a cause of PMP. Case presentation A 25-year old female with infertility was diagnosed with an isolated left ovarian tumor in a context of PMP. Histological examination revealed an ovarian teratoma containing an appendiceal-like structure with mucocele and LAMN, without any associated lesion of the appendix on full histological analysis. Molecular characterization of the ovarian lesion showed co-KRAS and GNAS mutations, as described in PMP of appendiceal origin, while only KRAS mutations are reported in primitive ovarian mucinous tumor. Conclusions Detection of co-KRAS and GNAS mutations in our case of ovarian teratomatous appendiceal-like mucocele with LAMN shows that when PMP derives from a mucinous ovarian lesion (with histological proof of none-appendiceal involvement), it is probably of a digestive teratomatous origin, emphasizing the need to actively search for tetatomatous signs in a context of ovarian PMP.

scholarly journals A case of Pseudomyxoma Peritonei of an unexpected origin.

2021 ◽  
Author(s):  
Marie Csanyi-Bastien ◽  
France Blanchard ◽  
Aude Lamy ◽  
Jean-Christophe Sabourin
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Ovarian Tumor ◽  
Histological Analysis ◽  
Mucinous Cystadenoma ◽  
Ovarian Teratoma ◽  
Mucinous Tumor ◽  
Case Presentation ◽  
Mucinous Neoplasm ◽  
Ovarian Lesion

Abstract Background:Pseudomyxoma peritonei (PMP) is a complex and partially understood disease defined by mucin deposits in the peritoneal cavity, mostly of appendiceal origin caused by the rupture of a mucocele often containing Low or High grade Appendiceal Mucinous Neoplasm (LAMN/HAMN). Other origins include primary ovarian mucinous cystadenoma or cystadenocarcinoma almost always with an associated teratoma, but to our knowledge no case of ovarian teratomatous appendiceal-like mucocele with LAMN has been reported as a cause of PMP.Case presentation:A 25-year old female with infertility was diagnosed with an isolated left ovarian tumor in a context of PMP. Histological examination revealed an ovarian teratoma containing an appendiceal-like structure with mucocele and LAMN, without any associated lesion of the appendix on full histological analysis. Molecular characterization of the ovarian lesion showed co-KRAS and GNAS mutations, as described in PMP of appendiceal origin, while only KRAS mutations are reported in primary ovarian mucinous tumor.Conclusions:Detection of co-KRAS and GNAS mutations in our case of ovarian teratomatous appendiceal-like mucocele with LAMN shows that when PMP derives from a mucinous ovarian lesion (with histological proof of none-appendiceal involvement), it is probably of a digestive teratomatous origin, emphasizing the need to actively search for tetatomatous signs in a context of ovarian PMP.

Ovarian Strumal Carcinoid Containing Appendiceal-Type Mucinous Tumor Patterns Presenting as Pseudomyxoma Peritonei

2015 ◽  
Vol 34 (3) ◽  
pp. 293-297 ◽  
Author(s):  
Enoe Quiñonez ◽  
Maolly Schuldt ◽  
Juan A. Retamero ◽  
Francisco F. Nogales
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Mucinous Tumor ◽  
Strumal Carcinoid

scholarly journals Mysterious Gelly Belly: a Case Report of Pseudomyxoma Peritonei and Literature Review

2020 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Literature Review ◽  
Pseudomyxoma Peritonei ◽  
Clinical Condition ◽  
Imaging Techniques ◽  
Abdominal Distension ◽  
Exploratory Laparotomy ◽  
Primary Site ◽  
Diffuse Abdominal Pain

Pseudomyxoma peritonei (PMP) is a rare clinical condition defined as extensive intraperitoneal spread of mucus associated with a variety of mucinous tumors. Although appendix has usually been implicated as the primary site, some reports found no cause. This case also describes a PMP with no identifiable primary site. A 52-year-old male presented with an abdominal distension evolving for 3 months associated with diffuse abdominal pain, imaging techniques objective intra peritoneal mucoid materials with septated ascites but it failed to identify the primary site. Exploratory laparotomy with Biopsy confirmed PMP but also failed to found the original site.

Case Report: Splenic Infarction in Infectious Mononucleosis due to Epstein–Barr Virus Infection

2021 ◽  
Author(s):  
Hiroaki Nishioka ◽  
Katsuma Hayashi ◽  
Hayato Shimizu
Keyword(s):  
Abdominal Pain ◽  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Rare Complication ◽  
Clinical Syndrome ◽  
Splenic Infarction ◽  
Epstein Barr Virus Infection ◽  
Serological Tests ◽  
Barr Virus ◽  
Epstein Barr

Epstein–Barr virus (EBV) is the most common cause of infectious mononucleosis (IM) and IM is a clinical syndrome typically characterized by fever, pharyngitis, and cervical lymph node enlargement. We describe the case of a 19-year-old man with IM complicated by splenic infarction. The patient visited our hospital because of upper abdominal pain without a fever and sore throat. Abdominal computed tomography revealed a low-density area in the spleen, which indicated splenic infarction. The next day, he developed a fever. After diminishing abdominal pain and fever, he developed pharyngitis accompanied by fever. Acute EBV infection was confirmed by serological tests. The patient was successfully managed with no specific therapy. Splenic infarction is a rare complication of IM and this case showed that splenic infarction can precede a fever and pharyngitis.

CT diagnosis and management of mesenteric torsion in a dog

2020 ◽  
Vol 8 (3) ◽  
pp. e001102
Author(s):  
Gabriel Carbonell Rossello ◽  
Ricardo Guillem Gallach ◽  
Manuel Jimenez Pelaez
Keyword(s):  
Abdominal Pain ◽  
Medical Treatment ◽  
Exploratory Laparotomy ◽  
Abdominal Ultrasound ◽  
Abdominal Distention ◽  
Intestinal Lumen ◽  
Ct Diagnosis ◽  
En Bloc ◽  
Diagnosis And Management ◽  
Small Intestines

An eight-year-old, 35 kg, female spayed Doberman Pincher dog was presented with peracute abdominal distention and severe abdominal pain associated with vomiting. Radiographs showed segmental gas and fluid-distended small intestines and loss of serosal detail. Abdominal ultrasound revealed segmental hypomotile, fluid distended small intestines and high amount of gas in the intestinal lumen. CT showed signs consistent with a segmental mesenteric torsion. Exploratory laparotomy and en bloc enterectomy of the torsioned necrotic segment of the jejunum (50 per cent approximately) was performed. The patient was discharged 1 week after surgery with some sporadic vomiting and diarrhoea, which resolved with medical treatment within a week.

Ovarian Mucinous Tumor Arising in Mature Cystic Teratoma Associated With Pseudomyxoma Peritonei

2008 ◽  
Vol 27 (1) ◽  
pp. 41-43 ◽  
Author(s):  
Collin J.R. Stewart ◽  
Reimar Junckerstorff ◽  
Tetsuya Tsukamoto
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Mucinous Tumor

Synchronous Ovarian and Appendiceal Mucinous Neoplasms in the Absence of Pseudomyxoma Peritonei

2017 ◽  
Vol 27 (2) ◽  
pp. 214-222
Author(s):  
Xianyong Gui ◽  
Jorge Escobar ◽  
Cheng-Han Lee ◽  
Máire A. Duggan ◽  
Martin Köbel
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Synchronous Tumors ◽  
Marker Panel ◽  
Ovarian Surface ◽  
Mucinous Neoplasms ◽  
Group 2 ◽  
High Degree ◽  
Ovarian Involvement ◽  
Appendiceal Perforation ◽  
Group 1

BackgroundSynchronous ovarian/appendiceal mucinous neoplasms sometimes occur in the absence of clinical pseudomyxoma peritonei (PMP), which raises a question about whether the 2 tumors could be independent.MethodsWe identified 11 cases of synchronous ovarian/appendiceal mucinous neoplasms without PMP and subclassified them into groups 1 and 2 based on the presence or absence of microscopic peritoneal/ovarian surface mucin deposits. A 7-marker panel (CK7, CK20, CDX2, PAX8, MUC1, MUC2, and MUC5AC) immunohistochemistry was performed on both tumors.ResultsBetween the 2 groups, there were no significant differences in age, laterality, size, and histology of ovarian/appendiceal tumors. In group 1, 2 of 4 cases developed PMP later, and both had ovarian surface and contralateral ovarian involvement and appendiceal perforation with microscopic mucin deposits on the peritoneum. No patients in group 2 developed PMP. All group 1 cases showed a high degree of concordance of immunoprofile between the synchronous tumors, with an identical expression of appendiceal pattern in greater than 90% of the markers. In group 2, only 1 of 7 cases showed concordance in all markers.ConclusionsIf peritoneal mucin deposits present, even microscopic and acellular, the synchronous tumors are most likely of a single appendiceal origin. Otherwise, they are more heterogeneous, and some may be truly dual primaries.

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