Occult Breast Cancer

Today breast cancer is the most common cancer type in women, in both developed and developing countries. However, occult breast cancer is a highly rare type in all breast cancers. For the first time in history to know, Halsted defined the term “occult breast cancer” with 2 cases of his’ in the journal, Annals of Surgery. We have 2 similar cases who were 52 and 61-years-old patients and presented our clinic with left axillary swelling and pain. On physical examination and with imaging techniques there wasn’t any primary lesion found. Examination of lymph nodes’ biopsy material was compatible with breast cancer metastasis for both of the patients and they were diagnosed with occult breast cancer. They underwent a modified radical mastectomy surgery and axillary curettage. Histopathologic examination of the excised breast material revealed T1 invasive breast cancer.International Journal of Human and Health Sciences Vol. 02 No. 04 October’18. Page : 239-243

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A Case of 10-Year Survival after Adrenalectomy for Isolated Adrenal Metastasis of Breast Cancer

Reports ◽

10.3390/reports3030022 ◽

2020 ◽

Vol 3 (3) ◽

pp. 22

Author(s):

Tsuyoshi Nakagawa ◽

Goshi Oda ◽

Akihiro Yano ◽

Hiroshi Kawachi ◽

Hiroyuki Uetake

Keyword(s):

Breast Cancer ◽

Hormone Therapy ◽

Cancer Metastasis ◽

Ductal Carcinoma ◽

Radical Mastectomy ◽

Breast Cancer Metastasis ◽

Adrenal Metastasis ◽

Pathological Examination ◽

Endoscopic Adrenalectomy ◽

Axillary Lymphadenectomy

Isolated adrenal metastasis of breast cancer is very rare, so adrenalectomy for breast cancer metastasis is rarely performed. The case of a breast cancer patient with five-year survival after resection of a left isolated adrenal metastasis is presented. A 70-year-old woman underwent left modified radical mastectomy and axillary lymphadenectomy for invasive ductal carcinoma (T2N1M0) 9 years earlier. At regular follow-up, a left adrenal mass, 4 cm in diameter, was seen on ultrasound examination and computed tomography (CT). Endoscopic adrenalectomy was performed. Pathological examination confirmed isolated adrenal metastasis of breast cancer. After surgery, hormone therapy was given for 5 years. Ten years after adrenalectomy, no metastatic lesions in other organs have been found on CT. Adrenalectomy for a metastatic adrenal tumor of breast cancer may provide survival benefits when combined with systemic hormone therapy and chemotherapy, particularly in patients with disease confined to the adrenal glands.

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Breast cancer metastasis to the conjunctiva

Vojnosanitetski pregled ◽

10.2298/vsp120322040b ◽

2013 ◽

Vol 70 (3) ◽

pp. 331-334 ◽

Cited By ~ 2

Author(s):

Anica Bobic-Radovanovic ◽

Dejan Rasic ◽

Marko Buta ◽

Radan Dzodic

Keyword(s):

Breast Cancer ◽

Female Patient ◽

Cancer Metastasis ◽

Lobular Carcinoma ◽

Hepatic Metastases ◽

Radical Mastectomy ◽

Excisional Biopsy ◽

Breast Cancer Metastasis ◽

Bulbar Conjunctiva ◽

Conjunctival Lesion

Introduction. Conjunctival metastasis is exceedingly rare, and it is, as a rule, a sign of advanced malignant disease with poor prognosis. We presented a female patient with breast cancer metastasis to the conjunctiva. Case report. A 45-yearold premenopausal female patient was presented with a solitary, yellowish, thin, demarcated lesion in the superior nasal quadrant of the bulbar conjunctiva of the left eye noted by chance a week earlier. There was no sign of irritation, and no pain, and no other functional or morphological problem in either eye or orbit. Five years before the appearance of conjunctival metastasis, breast carcinoma was diagnosed and the patient underwent chemotherapy, preoperative radiotherapy and radical mastectomy. Three years later, computed tomography scan showed metastasis in the left hepatic lobe with ascites and the patient underwent chemotherapy again. But, four months prior to the appearance of conjunctival lesion body scintigraphy showed multifocal sceletal lesions and nuclear magnetic resonance revealed diffuse hepatic metastases and bilateral ovarial tumors. Paliative radiotherapy and hormonal therapy (megestrol, 160 mg) were carried out. An excisional biopsy of the observed conjunctival lesion was performed under topical anesthesia and the material was subjected to histopathological (HP) examination. HP and immunohistochemical examinations established the presence of breast infiltrating lobular carcinoma metastatic to the conjunctiva. The patient showed rapid deterioration after intervention, and died after three weeks. Conclusion. A survival period less than one month after the appearance of conjunctival metastasis deserves attention because it is unexpected and has never been reported previously. It is not a rule that HP presentation of a metastatic lesion is so characteristic that it is possible to determine a primary tumor.

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Breast Cancer Metastasis to the Stomach That Was Diagnosed after Endoscopic Submucosal Dissection

Case Reports in Gastrointestinal Medicine ◽

10.1155/2016/2085452 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Masahide Kita ◽

Masashi Furukawa ◽

Masaya Iwamuro ◽

Keisuke Hori ◽

Yoshiro Kawahara ◽

...

Keyword(s):

Breast Cancer ◽

Endoscopic Submucosal Dissection ◽

Cancer Metastasis ◽

Radical Mastectomy ◽

Breast Cancer Metastasis ◽

Signet Ring Cell ◽

Axillary Lymph ◽

Submucosal Dissection ◽

Greater Curvature ◽

Cystic Disease Fluid Protein

A 52-year-old woman presented with stage IIB primary breast cancer (cT2N1M0), which was treated using neoadjuvant chemotherapy (epirubicin, cyclophosphamide, and paclitaxel). However, the tumor persisted in patchy areas; therefore, we performed modified radical mastectomy and axillary lymph node dissection. Routine endoscopy at 8 months revealed a depressed lesion on the gastric angle’s greater curvature, and histology revealed signet ring cell proliferation. We performed endoscopic submucosal dissection for gastric cancer, although immunohistochemistry revealed that the tumor was positive for estrogen receptor, mammaglobin, and gross cystic disease fluid protein-15 (E-cadherin-negative). Therefore, we revised the diagnosis to gastric metastasis from the breast cancer.

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Rare Metastases in Colorectum of Infiltrating Ductal Breast Cancer: A Rare Case Report and Review

10.21203/rs.3.rs-92091/v1 ◽

2020 ◽

Author(s):

Zhijun Zhang ◽

Tao Li ◽

Yuemin Li ◽

Dongxu Li ◽

Kai Zhang

Keyword(s):

Breast Cancer ◽

Cancer Metastasis ◽

Ductal Carcinoma ◽

Therapeutic Option ◽

Radical Mastectomy ◽

Left Breast ◽

Breast Cancer Metastasis ◽

Positron Emission ◽

Rare Case Report ◽

Lost To Follow Up

Abstract Background: Breast ductal carcinoma hardly metastasizes to colorectum and the effect of surgery is controversial. We treated one case of patients with breast ductal carcinoma metastasizes to colorectum with surgery and discussed current management experience of breast cancer metastasizing to colorectum by reviewing the literature. Case Presentation: A 37-year-old woman underwent a modified radical mastectomy three years ago for right breast cancer and developed left breast cancer with right breast cancer suspiciously metastasizing to colorectum, left ovary along with oviduct, pancreas, and left acetabulum according to positron emission tomography-computed tomography. Then she had chosen to give up further therapy but was admitted to our department complaining of shapeless feces and mucus pus and blood in stool for 2 years with the process of aggravating symptoms for recent 2 months. Colonoscopy revealed the existence of colorectal carcinoma. She received laparoscopic combined abdominal perineal resection and bilateral ovarian salpingectomy. Postoperative pathology as well as immunohistochemistry supported the origin of primary breast infiltrating ductal cancer. She remained tamoxifen therapy and was alive until she was lost to follow-up.Conclusions: Clinicians must pay attention to any gastro-intestinal symptoms of patients with a medical history of breast cancer since the incipient symptoms of breast cancer metastasis to colorectum are insidious. Definite diagnosis may be difficult even by endoscopy. Surgery should be considered as a therapeutic option and definite diagnostic means combined with immunohistochemistry.

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Meningioma as the host for metastatic breast cancer: A rare occurrence with important therapeutic impact

Surgical Neurology International ◽

10.25259/sni_148_2021 ◽

2021 ◽

Vol 12 ◽

pp. 314

Author(s):

Mohammad Hosseinzadeh ◽

Seyed Mehdi Ketabchi ◽

Seyed Ali Ahmadi ◽

Kasra Hendi ◽

Maysam Alimohamadi

Keyword(s):

Breast Cancer ◽

Cancer Metastasis ◽

Metastatic Breast ◽

Radical Mastectomy ◽

Rare Condition ◽

Breast Cancer Metastasis ◽

Histopathological Study ◽

Metastatic Tumors ◽

History Of ◽

High Index Of Suspicion

Background: Tumor-to-tumor metastasis is a rare condition. There are few reports of metastatic tumors within intracranial tumors, including meningiomas. Since some metastatic tumors have osteoblastic imaging pattern, it is not always easy to differentiate them from meningioma on preoperative studies. Case Description: A 60-year-old female referred to our center complaining about a progressive headache, nausea, and vomiting for the past month. She had a history of breast cancer treated with radical mastectomy (5 years ago) and adjuvant chemotherapy (until 1 year ago). Workups revealed a dural-based mass in the left temporobasal and midline subfrontal regions. Histopathological study showed breast cancer metastasis nests within the primary meningioma. Conclusion: As the diagnosis of metastatic nests inside a benign tumor, drastically alters postoperative adjuvant treatments, a high index of suspicion is needed evaluating tumors from patients with a history of systemic neoplasms.

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