scholarly journals Effects of Dietary Flaxseeds on Lipid Metabolism of Sprague-Dawley Rats

2004 ◽  
Vol 51 (7) ◽  
pp. 352-357 ◽  
Author(s):  
Masaaki Okabe ◽  
Midori Sakai ◽  
Norihide Maeda ◽  
Yumi Miyamoto ◽  
Hirofumi Tachibana ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Apple Pomace Consumption Favorably Alters Hepatic Lipid Metabolism in Young Female Sprague-Dawley Rats Fed a Western Diet

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1882 ◽  
Author(s):  
Roy Skinner ◽  
Derek Warren ◽  
Soofia Lateef ◽  
Vagner Benedito ◽  
Janet Tou
Keyword(s):  
Lipid Metabolism ◽  
Apple Pomace ◽  
Western Diet ◽  
Sprague Dawley ◽  
Hepatic Lipid Metabolism ◽  
Study Objective ◽  
Hepatic Lipid ◽  
Sprague Dawley Rats ◽  
Study Results ◽  
Isocaloric Diets

Apple pomace, which is a waste byproduct of processing, is rich in several nutrients, particularly dietary fiber, indicating potential benefits for diseases that are attributed to poor diets, such as non-alcoholic fatty liver disease (NAFLD). NAFLD affects over 25% of United States population and is increasing in children. Increasing fruit consumption can influence NAFLD. The study objective was to replace calories in standard or Western diets with apple pomace to determine the effects on genes regulating hepatic lipid metabolism and on risk of NAFLD. Female Sprague-Dawley rats were randomly assigned (n = 8 rats/group) to isocaloric diets of AIN-93G and AIN-93G/10% w/w apple pomace (AIN/AP) or isocaloric diets of Western (45% fat, 33% sucrose) and Western/10% w/w apple pomace (Western/AP) diets for eight weeks. There were no significant effects on hepatic lipid metabolism in rats fed AIN/AP. Western/AP diet containing fiber-rich apple pomace attenuated fat vacuole infiltration, elevated monounsaturated fatty acid content, and triglyceride storage in the liver due to higher circulating bile and upregulated hepatic DGAT2 gene expression induced by feeding a Western diet. The study results showed the replacement of calories in Western diet with apple pomace attenuated NAFLD risk. Therefore, apple pomace has the potential to be developed into a sustainable functional food for human consumption.

Effect of oral exposure to titanium dioxide nanoparticles on lipid metabolism in Sprague-Dawley rats

Nanoscale ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 5973-5986 ◽  
Author(s):  
Zhangjian Chen ◽  
Shuo Han ◽  
Pai Zheng ◽  
Di Zhou ◽  
Shupei Zhou ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Lipid Metabolism ◽  
Titanium Dioxide Nanoparticles ◽  
Oral Exposure ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

The present study investigated the effect of oral exposure to TiO2 NPs on lipid metabolism by serum lipidomics.

scholarly journals Effect of SALATRIM-Enriched Biscuit on Lipid Metabolism of Sprague-Dawley Rats.

1999 ◽  
Vol 46 (10) ◽  
pp. 638-644 ◽  
Author(s):  
Michiko NONAKA ◽  
Yoichi NAGAMORI ◽  
Koji YAMADA ◽  
Michihiro SUGANO
Keyword(s):  
Lipid Metabolism ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Dietary Effect of Guar Gum and its Partially Hydrolyzed Product on the Lipid Metabolism and Immune Function of Sprague-Dawley Rats

1999 ◽  
Vol 63 (12) ◽  
pp. 2163-2167 ◽  
Author(s):  
Koji YAMADA ◽  
Yoko TOKUNAGA ◽  
Atsushi IKEDA ◽  
Ken-ichi OHKURA ◽  
Soichi MAMIYA ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Immune Function ◽  
Guar Gum ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Effects of Chitosan Oligosaccharide on Plasma and Hepatic Lipid Metabolism and Liver Histomorphology in Normal Sprague-Dawley Rats

Marine Drugs ◽  
2020 ◽  
Vol 18 (8) ◽  
pp. 408 ◽  
Author(s):  
Shing-Hwa Liu ◽  
Rui-Yi Chen ◽  
Meng-Tsan Chiang
Keyword(s):  
Lipid Metabolism ◽  
Normal Control ◽  
Plasma Lipids ◽  
Control Diet ◽  
The Body ◽  
Chitosan Oligosaccharide ◽  
Sprague Dawley ◽  
Hepatic Lipid Metabolism ◽  
Hepatic Lipid ◽  
Sprague Dawley Rats

Chitosan oligosaccharide is known to ameliorate hypercholesterolemia and diabetes. However, some studies found that chitosan oligosaccharide might induce mild to moderate hepatic damage in high-fat (HF) diet-induced obese rats or diabetic rats. Chitosan oligosaccharide can be as a dietary supplement, functional food, or drug. Its possible toxic effects to normal subjects need to be clarified. This study is designed to investigate the effects of chitosan oligosaccharide on plasma and hepatic lipid metabolism and liver histomorphology in normal Sprague-Dawley rats. Diets supplemented with 5% chitosan oligosaccharide have been found to induce liver damage in HF diet-fed rats. We therefore selected 5% chitosan oligosaccharide as an experimental object. Rats were divided into: a normal control diet group and a normal control diet +5% chitosan oligosaccharide group. The experimental period was 12 weeks. The results showed that supplementation of 5% chitosan oligosaccharide did not significantly change the body weight, food intake, liver/adipose tissue weights, plasma lipids, hepatic lipids, plasma levels of AST, ALT, and TNF-α/IL-6, hepatic lipid peroxidation and anti-oxidative enzyme activities, fecal lipids, and liver histomorphology in normal rats. These findings suggest that supplementation of 5% chitosan oligosaccharide for 12 weeks may not induce lipid metabolism disorder and liver toxicity in normal rats.

Effect of Dietary Fats and Sesamin on the Lipid Metabolism and Immune Function of Sprague-Dawley Rats

1998 ◽  
Vol 62 (10) ◽  
pp. 1917-1924 ◽  
Author(s):  
Jiong-Yan GU ◽  
Yoko WAKIZONO ◽  
Aika DOHI ◽  
Michiko NONAKA ◽  
Michihiro SUGANO ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Immune Function ◽  
Dietary Fats ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Dietary Effects of Porphyran from Porphyra yezoensis on Growth and Lipid Metabolism of Sprague-Dawley Rats

2004 ◽  
Vol 10 (2) ◽  
pp. 147-151 ◽  
Author(s):  
Keisuke TSUGE ◽  
Masaaki OKABE ◽  
Takashi YOSHIMURA ◽  
Toshihisa SUMI ◽  
Hirofumi TACHIBANA ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Porphyra Yezoensis ◽  
Sprague Dawley ◽  
Dietary Effects ◽  
Sprague Dawley Rats
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