Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague–Dawley Rats

2015 ◽  
Vol 168 (1) ◽  
pp. 150-168 ◽  
Author(s):  
Weiwei Feng ◽  
Weijie Zhang ◽  
Ting Zhao ◽  
Guanghua Mao ◽  
Wei Wang ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Reproductive Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Related Enzyme ◽  
Chromium Malate

scholarly journals Apple Pomace Consumption Favorably Alters Hepatic Lipid Metabolism in Young Female Sprague-Dawley Rats Fed a Western Diet

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1882 ◽  
Author(s):  
Roy Skinner ◽  
Derek Warren ◽  
Soofia Lateef ◽  
Vagner Benedito ◽  
Janet Tou
Keyword(s):  
Lipid Metabolism ◽  
Apple Pomace ◽  
Western Diet ◽  
Sprague Dawley ◽  
Hepatic Lipid Metabolism ◽  
Study Objective ◽  
Hepatic Lipid ◽  
Sprague Dawley Rats ◽  
Study Results ◽  
Isocaloric Diets

Apple pomace, which is a waste byproduct of processing, is rich in several nutrients, particularly dietary fiber, indicating potential benefits for diseases that are attributed to poor diets, such as non-alcoholic fatty liver disease (NAFLD). NAFLD affects over 25% of United States population and is increasing in children. Increasing fruit consumption can influence NAFLD. The study objective was to replace calories in standard or Western diets with apple pomace to determine the effects on genes regulating hepatic lipid metabolism and on risk of NAFLD. Female Sprague-Dawley rats were randomly assigned (n = 8 rats/group) to isocaloric diets of AIN-93G and AIN-93G/10% w/w apple pomace (AIN/AP) or isocaloric diets of Western (45% fat, 33% sucrose) and Western/10% w/w apple pomace (Western/AP) diets for eight weeks. There were no significant effects on hepatic lipid metabolism in rats fed AIN/AP. Western/AP diet containing fiber-rich apple pomace attenuated fat vacuole infiltration, elevated monounsaturated fatty acid content, and triglyceride storage in the liver due to higher circulating bile and upregulated hepatic DGAT2 gene expression induced by feeding a Western diet. The study results showed the replacement of calories in Western diet with apple pomace attenuated NAFLD risk. Therefore, apple pomace has the potential to be developed into a sustainable functional food for human consumption.

Effect of oral exposure to titanium dioxide nanoparticles on lipid metabolism in Sprague-Dawley rats

Nanoscale ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 5973-5986 ◽  
Author(s):  
Zhangjian Chen ◽  
Shuo Han ◽  
Pai Zheng ◽  
Di Zhou ◽  
Shupei Zhou ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Lipid Metabolism ◽  
Titanium Dioxide Nanoparticles ◽  
Oral Exposure ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

The present study investigated the effect of oral exposure to TiO2 NPs on lipid metabolism by serum lipidomics.

The reproductive toxicity of organic compounds extracted from drinking water sources on Sprague Dawley rats: An in vitro study

2009 ◽  
Vol 25 (3) ◽  
pp. 284-293 ◽  
Author(s):  
Jiang Wu ◽  
Guanjiu Hu ◽  
Xiaoyi Wang ◽  
Dongmei Li ◽  
Hongxia Yu ◽  
...  
Keyword(s):  
Drinking Water ◽  
Organic Compounds ◽  
Reproductive Toxicity ◽  
In Vitro Study ◽  
Water Sources ◽  
Vitro Study ◽  
Sprague Dawley ◽  
Drinking Water Sources ◽  
Sprague Dawley Rats

scholarly journals Effect of SALATRIM-Enriched Biscuit on Lipid Metabolism of Sprague-Dawley Rats.

1999 ◽  
Vol 46 (10) ◽  
pp. 638-644 ◽  
Author(s):  
Michiko NONAKA ◽  
Yoichi NAGAMORI ◽  
Koji YAMADA ◽  
Michihiro SUGANO
Keyword(s):  
Lipid Metabolism ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Dietary Effect of Guar Gum and its Partially Hydrolyzed Product on the Lipid Metabolism and Immune Function of Sprague-Dawley Rats

1999 ◽  
Vol 63 (12) ◽  
pp. 2163-2167 ◽  
Author(s):  
Koji YAMADA ◽  
Yoko TOKUNAGA ◽  
Atsushi IKEDA ◽  
Ken-ichi OHKURA ◽  
Soichi MAMIYA ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Immune Function ◽  
Guar Gum ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

REPRODUCTIVE TOXICITY SCREEN OF TRIFLUOROIODOMETHANE (CF3I) IN SPRAGUE-DAWLEY RATS

1999 ◽  
Vol 11 (11) ◽  
pp. 1041-1055 ◽  
Author(s):  
D.E. Dodd ◽  
H.F. Leahy ◽  
M.L. Feldmann ◽  
J.H. English ◽  
A. Vinegar
Keyword(s):  
Reproductive Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats
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