The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection

Purpose Povidone-iodine (PI) is widely used to reduce the preoperative conjunctival bacterial load. This study aimed to evaluate the employment of PI 10% in an attempt to sterilize the ocular surface prior to cataract surgery, and to show that PI could be left in contact for 3 minutes. The viability of this exposure time in clinical practice, associated adverse events, and visual outcomes were documented. Methods In this prospective cohort study, phacoemulsification cataract surgery was performed in 604 patients by a single surgeon. Preoperative preparation was undertaken with PI 10%, applied to the cornea, conjunctival sac, eyelids, and periorbital skin with sterile cotton gauze. Povidone-iodine was then flushed onto the ocular surface. Operating room staff timed the precise duration of exposure. After the 3-minute preparation, the lids were thoroughly dried with fresh dry gauze. Results The median PI exposure time was 3.17 minutes, with an interquartile range of 0.25. All cases were followed up postoperatively at 1 day, 1 week, and 1 month. There were no complications attributable to PI. Visual outcomes were satisfactory. Conclusions Implementation of a preoperative prophylaxis protocol that used PI 10% with a 3-minute exposure time can be performed in clinical practice. The 3-minute exposure time had no adverse sequelae.

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Effectiveness of 0.66% Povidone-Iodine Eye Drops on Ocular Surface Flora before Cataract Surgery: A Nationwide Microbiological Study

Journal of Clinical Medicine ◽

10.3390/jcm10102198 ◽

2021 ◽

Vol 10 (10) ◽

pp. 2198

Author(s):

Rosario Musumeci ◽

Pasquale Troiano ◽

Marianna Martinelli ◽

Matteo Piovella ◽

Claudio Carbonara ◽

...

Keyword(s):

Cataract Surgery ◽

Ocular Surface ◽

Povidone Iodine ◽

Bacterial Species ◽

Bacterial Flora ◽

Bacterial Load ◽

Controlled Study ◽

Eye Drops ◽

Microbiological Analysis ◽

Contralateral Eye

A multicenter, nonrandomized, prospective, controlled study was conducted to evaluate, as perioperative prophylactic treatment, the anti-infective effectiveness of 0.66% povidone-iodine eye drops (IODIM®) against the bacterial flora of the conjunctival surface of patients who undergo cataract surgery. Eye drops containing 0.66% povidone-iodine were applied to the eye undergoing cataract surgery; the untreated contralateral eye was used as control. One hundred and twenty patients set to receive unilateral cataract surgery were enrolled in 5 Italian Ophthalmology Centers and pretreated for three days with 0.66% povidone-iodine eye drops. The contralateral eye, used as control, was left untreated. Conjunctival swabs of both eyes were collected at the baseline visit and after three days of treatment, just before the cataract surgery. A qualitative and quantitative microbiological analysis of bacterial presence was evaluated by means of bacterial culture, followed by identification. Methicillin resistance determination was also performed on staphylococci isolates. Bacterial load before and after treatment of the eye candidate for cataract surgery was evaluated and compared to the untreated eye. A reduction or no regrowth on the culture media of the bacterial load was observed in 100% of the study subjects. A great heterogenicity of bacterial species was found. The 0.66% povidone-iodine eye drops, used for three days prior to cataract surgery, were effective in reducing the conjunctival bacterial load. The 0.66% povidone-iodine eye drops (IODIM®) might represent a valid perioperative prophylactic antiseptic adjuvant treatment to protect the ocular surface from microbial contamination in preparation of the surgical procedure.

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Reducing bacterial contamination inside fluid catch bag in 25-gauge vitrectomy by use of 0.25 % povidone-iodine ocular surface irrigation

International Ophthalmology ◽

10.1007/s10792-012-9621-6 ◽

2012 ◽

Vol 33 (1) ◽

pp. 35-38 ◽

Cited By ~ 1

Author(s):

Hiroyuki Shimada ◽

Hiroyuki Nakashizuka ◽

Takayuki Hattori ◽

Yorihisa Kitagawa ◽

Ayumu Manabe ◽

...

Keyword(s):

Ocular Surface ◽

Bacterial Contamination ◽

Povidone Iodine ◽

Surface Irrigation ◽

25 Gauge Vitrectomy

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Evaluation of vitreous cellular activity following per-operative Povidone-iodine alone and combined per-operative Povidone-iodine with topical antibiotic after Intravitreal injection of anti-vascular endothelial growth factor Bevacizumab for retinal pathologies

Egyptian Journal of Ophthalmology, (Mansoura Ophthalmic Center) ◽

10.21608/ejomos.2021.58486.1009 ◽

2021 ◽

Vol 1 (3) ◽

pp. 168-175

Author(s):

Huma Saigol ◽

Seemab Akbar ◽

Abdul Rauf ◽

Khurram Chauhan ◽

shahzad Saeed ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Intravitreal Injection ◽

Povidone Iodine ◽

Vascular Endothelial ◽

Cellular Activity ◽

Topical Antibiotic ◽

Endothelial Growth Factor ◽

Retinal Pathologies

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Faculty Opinions recommendation of Intravitreal injection of 1.25% povidone iodine followed by vitrectomy using 0.025% povidone iodine irrigation for treating endophthalmitis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.735160694.793558369 ◽

2019 ◽

Author(s):

William Myers

Keyword(s):

Intravitreal Injection ◽

Povidone Iodine

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Assessment of Intravitreal Injection Training among U.S.-Based Ophthalmology Residents

Journal of Academic Ophthalmology ◽

10.1055/s-0039-1688912 ◽

2019 ◽

Vol 11 (01) ◽

pp. e43-e49

Author(s):

Jacob J. Liechty ◽

Michael J. Wilkinson ◽

Esther M. Bowie

Keyword(s):

United States ◽

Intravitreal Injection ◽

Povidone Iodine ◽

The United States ◽

Intravitreal Injections ◽

First Year ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Residency Program Directors ◽

Procedure Room

Purpose To describe the intravitreal injection training of ophthalmology residents in the United States in 2018. Design Cross-sectional survey. Methods An anonymous, 29-question, internet-based survey was emailed to 119 ophthalmology residency program directors with the instructions to forward the survey to their ophthalmology residents. Results A total of 117 ophthalmology residents (7.89%) responded to the survey. The majority of residents stated that their intravitreal injection training began during their first year of ophthalmology training, PGY 2 year, (92.3%). The majority of residents performed at least 25 injections per year (78.6%). All residents use antiseptic on the conjunctiva prior to the injection, 94% use a lid speculum, and 84.6% avoided talking in the procedure room. Most injections are performed with gloves (83.8%). A minority of residents stated that they are trained to use povidone-iodine on the eyelids prior to performing an injection (45.3%). Only 6.0% of residents claimed to use postinjection antibiotic drops. Performance of bilateral, simultaneous intravitreal injections was split with nearly half of residents not being trained in this method (47.9%). Conclusion Ophthalmology residents from across the country experience a variety of different injection protocols when being trained on how to perform intravitreal injections. Conjunctival antisepsis has reached a clear consensus while topics such as simultaneous, bilateral injections and eyelid antisepsis are still uncertain among the resident community.

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