Personalized Nutrition Caffeine Intake in Healthy Adults.

Abstract Objectives A longitudinal analysis was conducted on blood biomarker data from 1032 generally healthy individuals who used an automated, web-based personalized nutrition and lifestyle platform. Methods Combining the power of automation with the concepts of biological and behavioral personalization, we developed an online platform to produce individually customized nutrition and lifestyle recommendations for healthy adults, based on a panel of serum biomarkers. The scalable nature of the platform has allowed us to generate longitudinal biomarker data on 1032 generally healthy adults Results Biomarker changes during platform use were assessed, showing a trend toward normalcy for most biomarkers in those participants whose values were out of the clinically normal range at baseline. Finally, associations were found between the selection of specific interventions and corresponding biomarker changes, suggesting directions for future study. Conclusions We have used a rich longitudinal dataset of clinical biomarkers to uncover novel biological relationships while validating known ones. Furthermore, we have demonstrated that the personalized health platform described here associates with improvements in health parameters and shows promise for the validation of biomarker-intervention associations in a “real world” setting. By tracking a variety of biomarkers in free-living individuals, this platform provides a novel resource for exploration and hypothesis generation. With the advent of personalized health platforms such as the one described here, new efforts should be devoted to understanding the efficacy of their individual components while incorporating the valuable insights of participants. Funding Sources The scientists who conducted this study are either employed by the sponsoring company or serve as advisors to it. Thus, there is no separation between investigative team and funder, which provided support in the form of salaries, and was involved in the study design, data collection and analysis, decision to publish, and preparation of the manuscript. Supporting Tables, Images and/or Graphs

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Relationship between caffeine intake and response to stress stimuli among healthy adults

The Proceedings of the Annual Convention of the Japanese Psychological Association ◽

10.4992/pacjpa.84.0_pr-010 ◽

2020 ◽

Vol 84 (0) ◽

pp. PR-010-PR-010

Author(s):

Mariko Itoh ◽

Mingming Lin ◽

Yoshiharu Kim

Keyword(s):

Healthy Adults ◽

Caffeine Intake ◽

Response To Stress

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Does Personalized Nutrition Advice Improve Dietary Intake in Healthy Adults? A Systematic Review of Randomized Controlled Trials

Advances in Nutrition ◽

10.1093/advances/nmaa144 ◽

2020 ◽

Author(s):

Rachael Jinnette ◽

Ai Narita ◽

Byron Manning ◽

Sarah A McNaughton ◽

John C Mathers ◽

...

Keyword(s):

Systematic Review ◽

Behavior Change ◽

Dietary Intake ◽

Randomized Controlled Trials ◽

Risk Of Bias ◽

Healthy Adults ◽

Controlled Trials ◽

Personalized Nutrition ◽

Behavior Change Techniques ◽

Randomized Controlled

ABSTRACT Personalized nutrition (PN) behavior-change interventions are being used increasingly in attempts to improve dietary intake; however, the impact of PN advice on improvements in dietary intake has not been reviewed systematically. The aim of this systematic review was to evaluate the effect of PN advice on changes in dietary intake compared with generalized advice in healthy adults. Three databases (EMBASE, PubMed, and CINAHL) were searched between 2009 and 2020 for randomized controlled trials (RCTs) that tested the effect of PN and tailored advice based on diet, phenotype, or genetic information. The Evidence Analysis Library Quality Criteria checklist was used to conduct a risk-of-bias assessment. Information on intervention design and changes in nutrients, foods, and dietary patterns was extracted from the 11 studies meeting the inclusion criteria. Studies were conducted in the United States, Canada, or Europe; reported outcomes on 57 to 1488 participants; and varied in follow-up duration from 1 to 12 mo. Five studies incorporated behavior-change techniques. The risk of bias for included studies was low. Overall, the available evidence suggests that dietary intake is improved to a greater extent in participants randomly assigned to receive PN advice compared with generalized dietary advice. Additional well-designed PN RCTs are needed that incorporate behavior-change techniques, a broader range of dietary outcomes, and comparisons between personalization based on dietary, biological, and/or lifestyle information.

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Effect of dietary caffeine intake on serum lipid levels in healthy adults

Nutrition Research ◽

10.1016/s0271-5317(05)80556-1 ◽

1993 ◽

Vol 13 (6) ◽

pp. 639-647

Author(s):

Crystal D. Ricketts ◽

Lynn Forrester ◽

Patricia B. Brevard

Keyword(s):

Serum Lipid ◽

Healthy Adults ◽

Caffeine Intake ◽

Lipid Levels ◽

Serum Lipid Levels

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Effects of Caffeine Intake on Cardiopulmonary Variables and QT Interval after a Moderate-Intensity Aerobic Exercise in Healthy Adults: A Randomized Controlled Trial

BioMed Research International ◽

10.1155/2022/3170947 ◽

2022 ◽

Vol 2022 ◽

pp. 1-9

Author(s):

JaeHo Yu ◽

Jeong-Hun Lim ◽

Sang-Woo Seo ◽

DongYeop Lee ◽

JiHeon Hong ◽

...

Keyword(s):

Heart Rate ◽

Aerobic Exercise ◽

Healthy Adult ◽

Healthy Adults ◽

Moderate Intensity ◽

Caffeine Intake ◽

Qtc Interval ◽

Group I ◽

Significant Difference ◽

Before And After

Caffeine is considered a widely consumed natural and legal psychoactive stimulant with several effects on the body. The present study attempted to investigate the effects of caffeine consumed before and after a physical exercise on cardiovascular and cardiorespiratory functions in healthy adults. 36 healthy adult males were recruited and randomly allocated to one of the three (3) groups: group I (exercise without caffeine consumption), group II (caffeine beverage intake before exercise), and group III (caffeine beverage intake immediately after exercise). The heart rate (HR), QTc interval, blood pressure (BP), respiratory rate (RR), oxygen consumption (VO₂), and carbon dioxide emission (VCO₂) were measured at 0, 5, 10, and 15 min after the exercise. We observed a significant difference in all measured outcomes during the different recovery times in all the groups ( p < 0.05 ). HR, RR, SBP, VO2, and VCO2 gradually decreased with time, DBP contrarily increased with time, and the QTc showed an irregular pattern. We can affirm that ingestion of caffeine before and after moderate aerobic exercise slows down the parasympathetic stimulation, heart rate recovery, and the recovery of HR and QTc with no major effects on BP, RR, VO₂, and VCO₂ in healthy adult men.

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