scholarly journals Effects of Caffeine Intake on Cardiopulmonary Variables and QT Interval after a Moderate-Intensity Aerobic Exercise in Healthy Adults: A Randomized Controlled Trial

2022 ◽  
Vol 2022 ◽  
pp. 1-9
Author(s):  
JaeHo Yu ◽  
Jeong-Hun Lim ◽  
Sang-Woo Seo ◽  
DongYeop Lee ◽  
JiHeon Hong ◽  
...  

Caffeine is considered a widely consumed natural and legal psychoactive stimulant with several effects on the body. The present study attempted to investigate the effects of caffeine consumed before and after a physical exercise on cardiovascular and cardiorespiratory functions in healthy adults. 36 healthy adult males were recruited and randomly allocated to one of the three (3) groups: group I (exercise without caffeine consumption), group II (caffeine beverage intake before exercise), and group III (caffeine beverage intake immediately after exercise). The heart rate (HR), QTc interval, blood pressure (BP), respiratory rate (RR), oxygen consumption (VO₂), and carbon dioxide emission (VCO₂) were measured at 0, 5, 10, and 15 min after the exercise. We observed a significant difference in all measured outcomes during the different recovery times in all the groups ( p < 0.05 ). HR, RR, SBP, VO2, and VCO2 gradually decreased with time, DBP contrarily increased with time, and the QTc showed an irregular pattern. We can affirm that ingestion of caffeine before and after moderate aerobic exercise slows down the parasympathetic stimulation, heart rate recovery, and the recovery of HR and QTc with no major effects on BP, RR, VO₂, and VCO₂ in healthy adult men.

1999 ◽  
Vol 7 (4) ◽  
pp. 374-383 ◽  
Author(s):  
Richard A. Boileau ◽  
Edward McAuley ◽  
Demetra Demetriou ◽  
Naveen K. Devabhaktuni ◽  
Gregory L. Dykstra ◽  
...  

A trial was conducted to examine the effect of moderate aerobic exercise training (AET) on cardiorespiratory (CR) fitness. Previously sedentary participants, age 60-75 years, were randomly assigned to either AET treatment or a control group for 6 months. The AET consisted of walking for 40 min three times/week at an intensity that elevated heart rate to 65% of maximum heart rate reserve. The control group performed a supervised stretching program for 40 min three times/week. CR fitness was assessed before and after the treatments during a grade-incremented treadmill walking test. Both absolute and relative peak V̇O2 significantly increased (p < .01) in the AET group, whereas they decreased modestly in the control group. Maximum treadmill time increased significantly (p < .01) in the AET group relative to the control group. These results indicate that CR fitness as measured by peak V̇O2 modestly improves in the elderly with a moderate-intensity, relatively long-term aerobic exercise program.


2021 ◽  
Author(s):  
Ali Osali ◽  
Alireza Rostami

Abstract Backgrounds and ObjectivesThe use of anti-inflammatory supplements is important in improving the executive function of obese people. The aim of this research was to investigate the effect of 6 weeks of aerobic exercise with moderate intensity and consumption of nanocurcumin on IL1β, nitric oxide, and depression in women aged 60-65 with metabolic syndrome. Materials and Methods44 women with metabolic syndrome (MetS) were randomly selected and divided into four groups of 10, including MetS exercise+ Curcumin (MECU), MetS exercise (ME), MetS NanoCurcumin (MCU), MetS control (MC Training groups performed an exercise protocol of aerobic exercise for 6 weeks (three sessions per week). Blood samples were obtained before and after the training period for antioxidant indicators and lipid degradation measurement. Also, the Beck anxiety questionnaire was used for evaluating levels of anxiety. T-test and one-way analysis of variance were used for the evaluation of within-group and between-group differences, respectively.ResultsThere was a significant difference in IL1β, nitric oxide (NO), and depression before and after exercise in all three experimental groups (p≤0.05). Also, the results showed a significant difference in the level of NO and depression in the research groups. The highest decrease in these variables was observed in the aerobic training group and training with nanocurcumin consumption group (p≤0.05).ConclusionThese findings indicated that six-week nanocurcumin supplementation with aerobic training is a suitable method for reducing IL1β and NO and depression, preventing metabolic, cardiovascular, and inflammatory diseases in women with metabolic syndrome.Name of the registry: IR.SEMUMS.REC.1396.107Trial registration number: IRCT2017082335857N1


2021 ◽  
Vol 16 (1) ◽  
pp. 16-23
Author(s):  
Vibha Gangwar ◽  
Manish Kumar Verma ◽  
Ritesh Singh Gangwar ◽  
Nitin Ashok John ◽  
Rajani Bala Jasrotia

Background: Sedentary behavior is one of the leading modifiable risk factors for cardiovascular disease and all-cause mortality. Physical exercise exerts beneficial physiological effects on cardiovascular fitness. Different grades of physical exercise have different effects on cardiovascular health. Objective: To compare the effect of moderate and high intensity exercise training on heart rate variability (HRV) in sedentary office workers. Methods: This study was conducted on 40 healthy sedentary volunteers aged between 20-40 years of both the genders. Participants were distributed into two groups of 20 subjects each. Subjects of group I and group II performed moderate intensity and high intensity exercise respectively on bicycle ergometer for 12 weeks. Their 5- minute ECG recording was done by three channel physiograph, and frequency domain indices of HRV and heart rate (HR) were analyzed and compared before and after exercise training. Their blood pressure was also recorded and compared before and after exercise training. Independent sample t-test and paired sample ttest were used for statistical analysis. Results: HF, systolic and diastolic blood pressure reduced significantly after exercise in group II (p=0.015, 0.005, and 0.015 respectively) while HR and LF/HF ratio reduced in both group I and group II (p=0.000 for HR, and 0.034, 0.001 for LF/HF). The decrease in HR was greater after high intensity exercise than moderate intensity exercise (p= 0.025). Conclusion: Parasympathetic activity improves after moderate and high intensity exercise but improvement is more after high intensity exercise training. Therefore, high intensity exercise training is more beneficial than moderate intensity exercise training. J Bngladesh Soc Physiol 2021;16(1): 16-23


2016 ◽  
Vol 25 (2) ◽  
pp. 112-7
Author(s):  
Robert Stefanus ◽  
Sophie Yolanda ◽  
Radiana D. Antarianto

Background: Glial fibrillary acidic protein (GFAP) and heat shock protein -27 (HSP27) plasma can be used as the parameters of exercise-induced astrocyte reactivity. The American College of Sports Medicine (ACSM) recommends an exercise of 30 minutes or 10 minutes duration (each performing bout accumulated toward 30 minutes). The aim of this study was to compare GFAP and HSP27 plasma concentrations in young adults undergoing acute moderate-intensity aerobic exercise of different durations (10 minutes vs 30 minutes).Methods: An experimental study with pre-post design was conducted on 22 participants assigned to either 10 minutes or 30 minutes duration of single bout exercise. Blood sampling was performed before and after the exercise. GFAP and HSP27 plasma levels were measured with ELISA methods. Plasma GFAP and HSP27 levels before and after exercise were analyzed using paired t -test, while GFAP and HSP27 levels after exercise between the two groups were processed using unpaired t-test.Results: Plasma GFAP concentration decreased significantly (0,45 ng/mL) after 30 minutes of aerobic exercise (p<0.05). Plasma HSP27 concentration decreased significantly (1,71 ng/mL) after 10 minutes of aerobic exercise (p<0.05). No significant difference in plasma GFAP and HSP27 concentrations between 10 minutes (GFAP=0.49 ng/mL; HSP27=2.09 ng/mL) and 30 minutes duration of exercise (GFAP=0.45 ng/mL; HSP27=1,71 ng/mL).Conclusion: Acute moderate-intensity aerobic exercise with 10- and 30-minutes duration reduces the reactivity of astrocytes indication the increase of the synapse plasticity. The decrease in GFAP concentration occurred after 30 minutes of exercise and the decrease in HSP27 occurred after 10 minutes of exercise. These results showed that the body responds differently to different treatment duration in order to obtain the same effect on the body.


2019 ◽  
Vol 8 (2) ◽  
pp. 68-72
Author(s):  
Said Junaidi ◽  
Dian Listiarini

 ABSTRAK Tujuan penelitian ini untuk mengetahui pengaruh kombinasi latiahan aerobic dan asupan kafein untuk menurunkkan Body Mass Index dan Percent Body Fat Pada Wanita Overweight. Penelitian eksperimental ini dilakukan pada 12 wanita usia 19-22  tahun. Desain penelitian Treatment by subject, perlakuan 1  Latihan Aerobik 14 kali sesi dan perlakuan 2 pemberian Kafein dan Latihan Aerobik 14 kali sesi. Subyek diukur BB, TB (BMI), PBF (skinfold callifer) sebelum dan sesudah perlakuan. Hasil penelitian terjadi penurunan BMI pada P2 lebih  tinggi daripada P1 (0,75+0,39; 0,44+0,23), hasil uji t-test menunjukan hasil perbedaan yang signifikan 0,041 (p<0,05). Penurunan PBF pada P2 lebih tinggi dibandingkan P1 (0,84±0,23; 0,42±0,30), uji t-test menunjukan hasil perbedaan yang signifikan 0,001 (p<0,05). Simpulan dan saran: efek latihan aerobik dan pemberian kafein dapat menurunkan body mass index dan percent body fat pada wanita overweight usia 19-22 tahun. Kata kunci : BMI; kafein; latihan aerobik; overweight; PBF.  ABSTRACT Controlling body weight can be done with aerobic physical activity. Besides caffeine in the body's metabolism can also reduce body mass and percent fat, if both are combined can provide a more effective influence in reducing Body Mass Index and Percent Body Fat in Overweight of female. This experimental study was conducted on 12 women aged 19-22 years. Research design Treatment by subject, treatment 1; Aerobic exercise 14 sessions and treatment 2 Caffeine and Aerobic Exercise 14 sessions. Subjects measured BB, TB (BMI), PBF (skinfold callifer) before and after treatment. The results of the study showed a decrease in BMI in P2 higher than P1 (0.75 + 0.39; 0.44 + 0.23), the results of the t-test showed a significant difference of 0.041 (p <0.05). The decrease in PBF in P2 was higher than P1 (0.84 ± 0.23; 0.42 ± 0.30), the t-test showed a significant difference of 0.001 (p <0.05). Conclusion: the effect of the combination of aerobic exercise and caffeine intake is more effective in reducing body mass index and percent body fat in overweight of female. Keywords: aerobic exercise; BMI; caffeine; overweight; PBF.


2021 ◽  
Vol 25 (3) ◽  
pp. 172-177
Author(s):  
Javad Mahdiabadi

Background and Study Aim. Aerobic exercise improves fitness and quality of life and decreases mortality rate. Existence study determined the central hemodynamic adaptation after 8 weeks moderate-intensity continuous countryside jogging in non-athlete male. Material and Methods. Twenty-four untrained healthy male students (aged 20-22 years) volunteered and randomly divided into two groups: continuous training (CTG; n=12) and control (CG; n=12). Training program was countryside jogging for 45 min at 65-70% of Maximum Heart Rate (MHR), 3 days/week for 8-weeks performed. The CG group remained sedentary during the study period. Maximal oxygen consumption (VO2max) obtained using the step-test. Standard medical method impedance cardiograph was performed for hemodynamic parameters, during resting and after step-test conditions, before and after the study period. Results. Using t-test, after eight weeks: the resting heart rate (HR) in CTG group significantly decreased (P≤0.05). The systolic blood pressure (SBP) in CTG group decreased significantly at rest and after workload (P≤0.05). The diastolic blood pressure (DBP) did not change in both groups (P>0.05). The stroke volume (SV) increased significantly in CTG group at rest and after workload (P≤0.05).  The cardiac output (CO) did not change in both groups (P>0.05). The cardiac output (CO) did not change in both groups (P>0.05). The VO2max absolute and relative increased significantly in CTG group (P≤0.05). Significant difference between groups in SBP, SV, SVR and VO2max (absolute and relative) (P≤0.05). Conclusions. 8 weeks moderate-intensity continuous countryside jogging can improve the cardiac function and VO2max in selected healthy male. The regular exercise of aerobic with moderate intensity causes positive developments in systolic and diastolic blood pressures.


2021 ◽  
Author(s):  
Ali Osali ◽  
Alireza Rostami

Abstract Backgrounds and Objectives: The use of anti-inflammatory supplements is important in improving the function of obese people. The aim of this research was to investigate the effect of 6 weeks aerobic exercise with moderate intensity and consumption of nanocurcumin on IL1β, nitric oxide and depression in 60-65 years old women with syndrome metabolic. Materials and Methods: 44 women with metabolic syndrome (MetS) were randomly selected and divided into four groups of 10, including of MetS exercise+ Curcumin (MECU), MetS exercise (ME), MetS NanoCurcumin (MCU), MetS control (MC Training groups performed an exercise protocol of aerobic exercise for 6 weeks (three sessions per week). Blood samples were obtained before and after training period for antioxidant indicators and lipid degradation measurement. Also, Beck anxiety questionnaire used for evaluating levels of anxiety. T-test and one-way analysis of variance were used for the evaluation of within-group and between-group differences, respectively.Results: There was a significant difference in IL1β, NO and depression before and after exercise in all three experimental groups (p≤0.05). Also, the results showed a significant difference in the level of depression, NO and depression in the Reaserch groups. The highest decrease in these variables was observed in the aerobic training group and training with nanocurcumin consumption group (p≤0.05).Conclusion: These findings indicated that six-week nanocurcumin supplementation with aerobic training a suitable method for reducing IL1β and NO and depression preventing metabolic, cardiovascular and inflammatory diseases in women with syndrome metabolic.Name of the registry: IR.SEMUMS.REC.1396.107Trial registration number: IRCT2017082335857N1


Author(s):  
A. E. Chernikova ◽  
Yu. P. Potekhina

Introduction. An osteopathic examination determines the rate, the amplitude and the strength of the main rhythms (cardiac, respiratory and cranial). However, there are relatively few studies in the available literature dedicated to the influence of osteopathic correction (OC) on the characteristics of these rhythms.Goal of research — to study the influence of OC on the rate characteristics of various rhythms of the human body.Materials and methods. 88 adult osteopathic patients aged from 18 to 81 years were examined, among them 30 men and 58 women. All patients received general osteopathic examination. The rate of the cranial rhythm (RCR), respiratory rate (RR) heart rate (HR), the mobility of the nervous processes (MNP) and the connective tissue mobility (CTM) were assessed before and after the OC session.Results. Since age varied greatly in the examined group, a correlation analysis of age-related changes of the assessed rhythms was carried out. Only the CTM correlated with age (r=–0,28; p<0,05) in a statistically significant way. The rank dispersion analysis of Kruskal–Wallis also showed statistically significant difference in this indicator in different age groups (p=0,043). With the increase of years, the CTM decreases gradually. After the OC, the CTM, increased in a statistically significant way (p<0,0001). The RCR varied from 5 to 12 cycles/min in the examined group, which corresponded to the norm. After the OC, the RCR has increased in a statistically significant way (p<0,0001), the MNP has also increased (p<0,0001). The initial heart rate in the subjects varied from 56 to 94 beats/min, and in 15 % it exceeded the norm. After the OC the heart rate corresponded to the norm in all patients. The heart rate and the respiratory rate significantly decreased after the OC (р<0,0001).Conclusion. The described biorhythm changes after the OC session may be indicative of the improvement of the nervous regulation, of the normalization of the autonomic balance, of the improvement of the biomechanical properties of body tissues and of the increase of their mobility. The assessed parameters can be measured quickly without any additional equipment and can be used in order to study the results of the OC.


2007 ◽  
Vol 64 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Dusica Risovic ◽  
Lidija Petrovic ◽  
Natalija Kosanovic-Jakovic ◽  
Katarina Misailovic ◽  
Branislav Stankovic ◽  
...  

Background/Aim. Elevation in adduction is the most common pattern of vertical strabismus, and it is mostly treated with surgery. The results of weaking of inferior oblique muscle are very changeable. The aim of this study was to evaluate binocular vision using sensory tests before and one and six months after the surgery. Methods. A total of 79 children were divided in two groups: the first, with inferior oblique muscle of overaction (n = 52), and the second with dissociated vertical deviation (DVD), and primary inferior oblique muscle overaction (n = 27). We tested them by polaroid mirror test (PMT), Worth test at distance and near, fusion amplitudes on sinoptofore, Lang I stereo test and Wirt-Titmus stereo test. We examined our patients before and two times after the surgery for vertical strabismus. Results. Foveal suppression in the group I was found in 60.5% of the patients before, and in 56.4% after the surgery. In group II Foveal suppression was detected in 64.7% of the patients before, but in 55.6% 6 months after the surgery with PMT. Worth test revealed suppression in 23.5% of the patients before, and in 40.7% after the vertical muscle surgery. Parafoveal fussion persisted in about 1/3 of the patients before the surgery, and their amplitudes were a little larger after the surgery in the group I patients. Lang I stereo test was negative in 53.9% before and 51.9% after the surgery in the group I, and in 48.2% of the patients before and after the surgery in the group II patients. Wirt-Titmus stereo test was negative in 74.5% of the patients before and in 72.9% after the surgery in the group I, but in the group II it was negative in 70.8% before and in 68.0% of the patients 6 months after the surgery. Conclusion. Binocular responses were found after surgery in 65.7% of the patients the group I and in 55.6% patients the group II. There was no significant difference between these two groups, but binocular responses were more often in the patients of the group I.


2020 ◽  
Vol 14 (1) ◽  
pp. 108-114
Author(s):  
Kalpana Kulkarni ◽  
Rahul Patil

Background: Bupivacaine with opioid is commonly used for labour epidural analgesia. Ropivacaine is considered as an alternative to bupivacaine due to its lower cardiovascular complications. However, there is a controversy regarding the efficacy of these drugs as some studies suggest equivalent action, whereas others report that ropivacaine produces less motor blockade. The study aimed to compare the effect of ropivacaine-fentanyl and bupivacaine-fentanyl for labour analgesia. Materials and Methods: The prospective randomized study was performed on 60 parturients, divided into two groups of 30 subjects each. Group I received 10ml of bupivacaine 0.1% + fentanyl 2µg/ml and Group II received 10ml of ropivacaine 0.1% + fentanyl 2µg/ml by epidural catheter. Pre-anaesthetic evaluation was performed on all the participants and all were administered metoclopramide 0.25mg/kg and ondansetron 0.08-0.1mg/kg intravenously as premedication. The baseline and post anaesthesia systolic, diastolic blood pressure, heart rate, VAS score, degree of motor block, sedation and APGAR score of the baby were recorded. The data were tabulated and statistically analyzed. Results: When compared, there was no significant difference in systolic/diastolic blood pressure in two groups except at 360 min where diastolic pressure was low in group II. Significantly higher heart rate at 30 min (P=0.0003), 120 min (0.006), and 300 min (P=0.001) was observed in group I subjects. VAS score was significantly less at 180 min (P=0.019) and 300 min (P=0.019) in group II. Adverse effects such as fetal bradycardia, nausea/vomiting and hypotension observed were clinically insignificance when compared in two groups. Conclusion: Bupivacaine and ropivacaine produce an equal degree of analgesia and hemodynamic stability in 0.1% of concentration when added with 2µg/ml fentanyl . However, heart rate was well maintained with lower VAS scores in group II receiving ropivacaine. No significant difference in the side effects between the two groups. Hence, Ropivacaine can be used as a safe alternative to bupivacaine for labour epidural analgesia.


Sign in / Sign up

Export Citation Format

Share Document