Cross Sectional Survey on the Burden, Impacts and Causes of Hepatitis C Virus (HCV) Outbreak in South West Region in Burkina Faso

Author(s):  
2003 ◽  
Vol 18 (7) ◽  
pp. 841-850 ◽  
Author(s):  
SANDRA M. GIFFORD ◽  
MARY L. O'BRIEN ◽  
GABRIELE BAMMER ◽  
CATHY BANWELL ◽  
MARK STOOVE

2005 ◽  
Vol 20 (1) ◽  
pp. 79-86 ◽  
Author(s):  
SANDRA M GIFFORD ◽  
MARY L O'BRIEN ◽  
ANTHONY SMITH ◽  
MEREDITH TEMPLE-SMITH ◽  
MARK STOOVÉ ◽  
...  

Author(s):  
Yin Liu ◽  
Xia Zou ◽  
Wen Chen ◽  
Cheng Gong ◽  
Li Ling

We aimed to evaluate the status and barriers related to hepatitis C virus (HCV) treatment among Chinese methadone maintenance treatment (MMT) clients, and the willingness and barriers of patients to accept directly observed treatment (DOT) service and oral direct-acting antivirals (DAAs). We conducted a cross-sectional survey from July to October 2017 in Guangdong Province, China, involving 678 HCV antibody-positive MMT patients. If they reported being infected with HCV, then their HCV treatment experience, willingness to use DOT and DAAs, along with any barriers, were collected. Logistic regression analysis was used to identify the correlates of initiating HCV treatment. Among those reporting HCV infection (54%, 366/678), 39% (144/366) initiated treatment; however, 38% (55/144) interrupted and 55% (79/135) delayed treatment for 15 months. Seventy-five percent (273/366) and 53% (195/366) were willing to use DOT and DAAs, respectively. Unaffordable medical costs and insignificant symptoms were the major barriers to HCV treatment and accepting DOT or DAAs. The lack of a stable residence, being a woman, and having ever injected drugs were all associated with a low probability of initiating treatment (p < 0.05). This study highlights a limited uptake of HCV treatment among MMT patients, and a need to strengthen the popularity of DOT and DAAs and integrate them into Chinese MMT clinics.


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