Efficacy of Gastrostomy Tube Coated With Povidone-iodine for Reducing Peristomal Infection Rate After PEG Insertion

A series of 418 patients with lacerations of the hands were allocated randomly to a control group or to a group where the injury was treated with povidone iodine before suture. The incidence of infected and imperfectly healed wounds was determined seven days later. As well as the effect of povidone iodine on infection, thirteen other factors were also analysed. The overall infection rate of 5.0% and the 38.5% imperfect healing rate were not significantly affected by povidone iodine treatment, although both were reduced. The figures of four other trials were combined with this trial and this showed a significant effect of povidone iodine treatment. There were no adverse reactions to povidone iodine. It is therefore recommended that hand lacerations should be treated with povidone iodine prior to suture. Other factors found to be significantly important in wound infection or imperfect healing were the condition of the dressing, the part of the hand injured and pain. Patients should be strongly advised to keep their dressing clean and dry.

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Efficacy of Povidone Iodine Solution in the Prevention of Surgical Site Infections in Minimally Invasive Instrumented Spinal Fusion Surgery

Global Spine Journal ◽

10.1177/2192568220975385 ◽

2020 ◽

pp. 219256822097538

Author(s):

Hsi-Hsien Lin ◽

Po-Hsin Chou ◽

Hsuan-Hsiao Ma ◽

Yu-Wei Chang ◽

Shih-Tien Wang ◽

...

Keyword(s):

Bone Graft ◽

Infection Rate ◽

Povidone Iodine ◽

Autologous Bone Graft ◽

Deep Infection ◽

Surgical Wound ◽

Fusion Surgery ◽

Spinal Fusion Surgery ◽

Autologous Bone ◽

Povidone Iodine Solution

Study Design: A retrospective case-controlled study. Objectives: To evaluate overall infection rate and adverse event after harvesting bone graft soaking and surgical wound irrigation by povidone iodine solution (PVI) in the minimally invasive instrumented spinal fusion surgery. In order to reduce the rate of surgical site infection in spinal surgery, surgical wound irrigation by povidone iodine solution has been well-established. However, the efficacy of autologous bone graft soaking by PVI has not been evaluated before. Methods: This is a retrospective cohort study. 120 patients were enrolled in the PVI group and compared with 124 patients in the historical cohort. In the PVI group, the harvesting autologous bone graft was soaking and the surgical wound was also irrigated by diluted PVI solution. The outcome measures were overall infection rate, superficial wound infection and deep infection. In addition, the delayed union of the fusion mass was also evaluated through the radiograph evaluation. Results: Both groups shared similar patient demographics instead of body mass index. The use of PVI solution had decreased the overall infection rate (0% versus 4.03%, p = 0.026) and deep infection rate (0% versus 3.23%, p = 0.047). In addition, there was no delayed bone healing in the PVI group after autologous bone graft soaking. Conclusions: In this study, we conclude that harvested autologous bone graft after PVI soaking in spinal fusion surgery can decrease the incidence of deep infection.

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Further evidence for the presence of Renibacterium salmoninarum in salmonid eggs and for the failure of povidone-iodine to reduce the intra-ovum infection rate in water-hardened eggs

Journal of Fish Diseases ◽

10.1111/j.1365-2761.1984.tb00921.x ◽

1984 ◽

Vol 7 (3) ◽

pp. 173-182 ◽

Cited By ~ 74

Author(s):

T. P. T. EVELYN ◽

J. E. KETCHESON ◽

L. PROSPERI-PORTA

Keyword(s):

Infection Rate ◽

Povidone Iodine ◽

Renibacterium Salmoninarum ◽

Salmonid Eggs

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Decrease in Infection Rate Following Use of Povidone-Iodine During Transrectal Ultrasound Guided Biopsy of the Prostate: A Double Blind Randomized Clinical Trial

Iranian Journal of Radiology ◽

10.5812/iranjradiol.7561 ◽

2012 ◽

Vol 9 (2) ◽

pp. 67-70 ◽

Cited By ~ 18

Author(s):

Mahyar Ghafoori ◽

Madjid Shakiba ◽

Hamidreza Seifmanesh ◽

Kamal Hoseini

Keyword(s):

Clinical Trial ◽

Randomized Clinical Trial ◽

Infection Rate ◽

Povidone Iodine ◽

Transrectal Ultrasound ◽

Ultrasound Guided ◽

Double Blind ◽

Guided Biopsy ◽

Ultrasound Guided Biopsy

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Exit-Site Care in Austrian Peritoneal Dialysis Centers — a Nationwide Survey

Peritoneal Dialysis International ◽

10.1177/089686080902900319 ◽

2009 ◽

Vol 29 (3) ◽

pp. 330-339 ◽

Cited By ~ 28

Author(s):

Gertrude Kopriva–Altfahrt ◽

Paul König ◽

Michael Mündle ◽

Friedrich Prischl ◽

Johannes M. Roob ◽

...

Keyword(s):

Peritoneal Dialysis ◽

Infection Rate ◽

Sodium Hypochlorite ◽

Povidone Iodine ◽

Nationwide Survey ◽

Infection Rates ◽

Exit Site ◽

Exit Site Infection ◽

Staff Members ◽

Octenidine Dihydrochloride

Background Catheter-associated infections markedly contribute to treatment failure in peritoneal dialysis (PD) patients. There is much controversy surrounding prophylactic strategies to prevent these infections. Methods In this nationwide multicenter study we analyzed strategies to prevent catheter-associated infections as performed in Austrian PD centers in 2006. A questionnaire was sent to all 23 PD centers in Austria. Results Ten different catheter models were used in the 332 patients being treated in the 23 Austrian PD centers. Systemic antibiotics prior to catheter placement were given by 17 of the 23 PD centers (glycopeptides, n = 7; cephalosporins, n = 10). Nasal swabs were taken preoperatively by 17 PD centers; nasal Staphylococcus aureus carriers were treated prophylactically with mupirocin cream in 15 of these centers. Dressing change was routinely performed in 318 of 332 chronic PD patients (nonocclusive film dressing, n = 58; gauze dressing, n = 260). Disinfectants for chronic exit-site care included povidone iodine ( n = 155), sodium hypochlorite ( n = 31), povidone iodine + sodium hypochlorite together ( n = 102), and octenidine dihydrochloride/phenoxyethanol ( n = 17). Water+non-disinfectant soap or 0.9% sodium chloride was administered as a cleansing agent to the exit site by 27 patients. Routine S. aureus screening (nasal and/or exit-site swabs) in chronic PD patients was performed in 12 PD centers; carriers were treated with mupirocin cream in 11 of these centers. Dialysis staff members were screened for S. aureus in 8 PD centers and spouses were screened for S. aureus in 5 PD centers. The overall exit-site infection rate was 1 episode/43.9 patient-months, tunnel infection rate was 1 episode/88.9 patient-months, and peritonitis rate was 1 episode/51.0 patient-months. Patients of centers that have installed a prophylaxis protocol for treating S. aureus carriers had lower mean infection rates compared with those not using such a protocol. Conclusion Various individual prophylactic strategies are used to prevent catheter-associated infections in Austrian PD centers. Infection rates are within the range reported in the literature. There is still scope for improvement in some centers ( e.g., by establishing a prophylaxis protocol).

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Povidone-iodine irrigation combined with Vancomycin powder lowers infection rates in pediatric deformity surgery

Spine Deformity ◽

10.1007/s43390-021-00333-3 ◽

2021 ◽

Author(s):

Rolando Figueroa Roberto ◽

Flynn Andrew Rowan ◽

Deepak Nallur ◽

Blythe Durbin-Johnson ◽

Yashar Javidan ◽

...

Keyword(s):

Surgical Site Infection ◽

Infection Rate ◽

Povidone Iodine ◽

Small Sample Size ◽

Statistical Significance ◽

Tertiary Care ◽

Small Sample ◽

Site Infection ◽

Infection Rates ◽

Vancomycin Powder

Abstract Background Surgical site infection is a morbid, devastating complication after spinal procedures. Studies have investigated the effect of wound lavage with 3.5% Povidone-iodine solution or the use of intrawound Vancomycin powder. We examined the effect of Povidone-iodine irrigation, intrawound Vancomycin powder, or a combination of both agents in a tertiary care Pediatric Hospital. Methods We queried our health system database for patients undergoing spinal surgery over an eight-year span between January 2008 and June 2016 and identified patient cohorts who received no intervention, intrawound Vancomycin alone, Povidone-iodine irrigation alone, or a combination of both agents. Infection rates were determined. The effect of treatment on outcome was analyzed using a logistic regression model. Results 475 patients were identified who met study inclusion criteria. 88 non-neuromuscular patients received no intra-operative agent. The surgical site infection (SSI) rate in this group of patients was 10%. For the 194 non-neuromuscular scoliosis patients who received Povidone-iodine and Vancomycin powder, the infection rate was reduced to 0.7%. The SSI rate in the 180 non-neuromuscular patients who were treated with Vancomycin powder alone was 1.4%. 13 patients were treated with Povidone-iodine lavage only, with a small sample size precluding statistical comparison. Infection rate in the 132 neuromuscular disease patients decreased from 14 to 7% overall during this time span: while the odds ratio of infection was reduced in all neuromuscular treatment groups receiving intra-operative measures, statistical significance was not reached in any neuromuscular group studied. Conclusions A protocol using combined 3.5% weight/volume Povidone-iodine and Vancomycin powder was associated with the lowest infection rate in our non-neuromuscular patient population and should be considered as a low cost intervention in pediatric patients undergoing spinal deformity procedures. Level of evidence Level II.

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