Effect of the introducer technique compared with the pull technique on the peristomal infection rate in PEG: a meta-analysis

2012 ◽  
Vol 75 (5) ◽  
pp. 988-996 ◽  
Author(s):  
Paulo Moacir Oliveira Campoli ◽  
Adriano Augusto Peclat de Paula ◽  
Luana Gomes Alves ◽  
Marilia Dalva Turchi
Keyword(s):  
Infection Rate ◽  
Meta Analysis ◽  
Peristomal Infection

scholarly journals Endemic human fasciolosis in the Bolivian Altiplano

2006 ◽  
Vol 135 (4) ◽  
pp. 669-674 ◽  
Author(s):  
M. PARKINSON ◽  
S. M. O'NEILL ◽  
J. P. DALTON
Keyword(s):  
Rural Communities ◽  
Infection Rate ◽  
Meta Analysis ◽  
Emerging Disease ◽  
La Paz ◽  
Lake Titicaca ◽  
Age Related ◽  
Epidemiological Surveys ◽  
Bolivian Altiplano

SUMMARYFasciolosis, caused by trematodes of the genusFasciola, is an emerging disease of humans. One of the highest levels of human fasciolosis hepatica is found amongst the indigenous Aymaran people of the Northern Bolivian Altiplano. A meta-analysis of epidemiological surveys from 38 communities in the region demonstrates that fasciolosis has been endemic in the region since at least 1984 and is a zoonosis of rural communities. Human and bovine fasciolosis is associated with the communities lying in the plain from Lake Titicaca to La Paz, predominantly in the Los Andes province. In Los Andes incidences of up to 67% of population cohorts were found, and prevalence is age-related with the highest infection rate in children aged 8–11 years.

scholarly journals Induction Therapy With Mesenchymal Stem Cells in Kidney Transplantation: A Meta-Analysis

2020 ◽  
Author(s):  
Lingfei Zhao ◽  
Chenxia Hu ◽  
Fei Han ◽  
Dajin Chen ◽  
Jun Cheng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Kidney Transplantation ◽  
Opportunistic Infection ◽  
Infection Rate ◽  
Induction Therapy ◽  
Meta Analysis ◽  
Graft Function ◽  
Renal Graft ◽  
Post Surgery

Abstract Objective The aim of this meta-analysis was to evaluate the therapeutic effects of mesenchymal stem cells (MSCs) versus other regimens as induction therapy in kidney transplantation patients.Methods PubMed, Embase, EBSCO, Ovid and the Cochrane Library were searched to identify prospective clinical trials which compared MSCs with other regimens as induction therapy in renal allograft.Results Four studies with five cohorts were contained, including a total of 301 patients. The pooled results revealed that the MSCs therapy had a lower 1-year infection rate (RR=0.73, 95% CI: 0.58–0.93, P=0.01), espeicially for 1-year opportunistic infection rate (RR=0.59, 95% CI: 0.37–0.93, P=0.02). There were no significant differences between the two protocols regarding 1-year acute rejection (AR) rate (RR=0.69, 95% CI: 0.42–1.14, P=0.15), 1-year graft survival rate (RR=0.99, 95% CI: 0.95–1.03, P=0.74), delayed graft function (DGF) rate (RR=0.72, 95% CI: 0.34–1.50, P=0.38) and renal graft function at 1 month (MD=2.4, 95% CI: -7.41– 12.22, p=0.63), 3 months (MD=0.91, 95% CI: -4.17– 5.98, p=0.73), 6 months (MD=-1.41, 95% CI: -5.69– 2.87, p=0.52), 12 months (MD=1.25, 95% CI: -3.89– 6.4, p=0.63) post surgery. Subgroup analysis demonstrated 1-year AR rate, DGF rate and renal graft function at 12 month post surgery did not reach to a significant difference between low-dose calcineurin inhibitors (CNIs) group with standard-dose CNIs group, indicating successful CNIs withdrawal in combination with MSCs treatment. Meanwhile, when applied MSCs as an alternative standard induction therapy regimen, all of those outcomes mentioned above were also comparable with those in MSCs plus standard induction therapy group.Conclusion Induction therapy of MSCs has similar inducing immune tolerance effects on the recipients in kidney transplantation compared with that of other regimens. However, regarding the long term effect, as represented by 1-year infection rate, 1-year opportunistic infection rate and CNIs withdrawl, MSCs therapy has a significant advantage.

Comparing Surgical Site Infection for Open and Endoscopic Component Separation

2019 ◽  
Vol 85 (4) ◽  
pp. 350-352
Author(s):  
Derek S. Palmer ◽  
Conner C. Mcdaniel ◽  
Navdeep S. Samra ◽  
F. Dean Griffen
Keyword(s):  
Quality Improvement ◽  
Surgical Site Infection ◽  
Abdominal Wall ◽  
Infection Rate ◽  
Meta Analysis ◽  
Abdominal Wall Hernia ◽  
Component Separation ◽  
Separation Technique ◽  
P Value ◽  
Site Infection

In March 2016, we reported the SSI rate at LSU Health for all abdominal wall hernia repairs performed between 2011 and 2013. Among the 263 repairs, the infection rate averaged 6.8 per cent. Given the diversity of repairs, this global percentage lacks relevance, but looking at subsets provides meaningful insights. For example, SSI was 1.8 per cent among 55/263 laparoscopic repairs and 8.2 per cent among 206/263 open repairs. The infection rate of 26.3 per cent among the 19 open component separation cases was especially noteworthy and bothersome. Even though there was no mortality in any subset, the vast majority of the morbidity and costs involved repairs with open component separations. A meta-analysis published in 2016 revealed a likely SSI benefit for the endoscopic component separation technique (ECST) over the open CST. Since that report, we have focused our quality improvement efforts on this subset of challenging cases and have replaced CST with ECST. Our data now include results from 33 hernia repairs with either CSTor ECST that were performed between November 2011 and April 2018. Twenty-four of 33 patients had CSTwith an SSI rate of 37.5 per cent (9 of 24). Nine of 33 had ECST with 0 per cent SSI (P value = 0.039). These results mirror the findings reported in the meta-analysis.

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