Complete Melkersson-Rosenthal syndrome: an exceptional cause of facial nerve palsy

2021 ◽  
Vol 3 (3) ◽  
pp. 01-04
Author(s):  
Khadija El Bouhmadi ◽  
Youssef Oukessou ◽  
Bushra Abdulhakeem ◽  
Houda Chaouki ◽  
Meryem Regragui ◽  
...  
Keyword(s):  
Facial Palsy ◽  
Histopathological Examination ◽  
Frontal Area ◽  
Facial Oedema ◽  
Unknown Etiology ◽  
Duration Of Symptoms ◽  
Peripheral Facial Palsy ◽  
Oral Corticosteroids ◽  
Grade Ii ◽  
Cardinal Symptoms

Melkersson-Rosenthal syndrome (MRS) is a rare disease, with unknown etiology characterized by oro-facial oedema, fissuring tongue and peripheral facial palsy. The mainstay treatment is corticosteroids. We report the case of a 38-year old female, who presented six recurrent episodes of left peripheral facial palsy associated with simultaneous oedema of the median frontal area, treated successfully by short course oral corticosteroids with neuromuscular facial re-education. However, the recovery of the last episode was incomplete and the patient kept a left House-Brackmann grade II facial palsy at six months. The median frontal area was slightly inflammatory, being the location of simultaneous repetitive oedema and the tongue was fissured. These cardinal symptoms realise the complete triad of Melkersson-Rosenthal syndrome (MRS). The histopathological examination of the lip biopsy showed lymphocytic inflammation around the blood vessels. Since the residual facial palsy was graded as mild dysfunction, the frontal oedema fully recovered and the fissured tongue was not painful, the treatment consisted on appropriate neuromuscular re-education. The 6 months follow-up showed no recurrence with a stable grade II left facial palsy. We present this case to supplement the rare literature data concerning the management of this rare entity. Patients should be prepared to the risk of recurrent episodes with longer duration of symptoms and more incomplete recoveries, which may indicate other therapeutic options.

scholarly journals A rare case of acquired infantile Bell’s palsy

2021 ◽  
Vol 8 (7) ◽  
pp. 1316
Author(s):  
Lakshmi Mulinja ◽  
Thanzir Mohammed ◽  
Varun Govindarajan ◽  
Mallesh Kariyappa
Keyword(s):  
Case Report ◽  
Facial Palsy ◽  
Rare Case ◽  
Bell’S Palsy ◽  
Acute Onset ◽  
Spontaneous Resolution ◽  
Bell's Palsy ◽  
Peripheral Facial Palsy ◽  
Oral Corticosteroids ◽  
Viral Illness

Bell’s palsy, an acute onset, acquired, isolated peripheral facial palsy, usually follows a viral illness, is common disorder post infancy to adolescence. It has a favourable prognosis with spontaneous resolution, or with use of oral corticosteroids. Its presentation in early infancy is very unusual, as in our case report of 3 month old infant with an ovoid mass lesion in parotid, which disappeared after therapy with corticosteroids with no residual deficit.

scholarly journals Perigastric Hyaline-Vascular Variant Castleman’s Disease

2021 ◽  
pp. 632-638
Author(s):  
Yu Ming Jin ◽  
Gui Ying Jing
Keyword(s):  
Histopathological Examination ◽  
Immunohistochemical Analysis ◽  
Lymphoproliferative Disease ◽  
Castleman Disease ◽  
Unknown Etiology ◽  
Mesenchymal Tumors ◽  
Imaging Characteristics ◽  
Contrast Enhanced ◽  
Hyaline Vascular Variant ◽  
Vascular Variant

Castleman disease (CD) is a rare chronic lymphoproliferative disease with unknown etiology and pathogenesis disease. When the lesion is located in the mediastinum, the diagnosis of CD is easy. However, if the lesion presents as a perigastric mass mimicking other subserosal gastric mesenchymal tumors, the diagnosis can be challenging. As few sonographic manifestations of hyaline-vascular variant CD, especially contrast-enhanced ultrasound (CEUS) imaging, as well as computed tomography (CT) and histopathological imaging, have been reported in literature, this case may provide a vivid example of a comprehensive CEUS and CT usage in the diagnosis and surgery with regard to CD. This report presents a case of a 50-year-old female diagnosed with hyaline-vascular variant CD in a random physical examination, the ultrasound examination first revealed a 24.3 mm × 15.4 mm hypoechogenic lesion abutting the stomach, esophagus, and liver, which was under the suspicion of gastrointestinal stromal tumor. Following a series of medical examinations, including CEUS, CT, postoperative histopathological examination, and immunohistochemical analysis, the patient was diagnosed with hyaline-vascular variant unicentric CD. After the mass was completely excised through laparoscopic surgery, the woman recovered very well without recurrence during a follow-up period of 15 months. Thus, mastering ultrasound and CT-imaging characteristics of CD and applying ultrasound and CT examination together would do help to preoperative diagnosis.

scholarly journals Placental Complement Activation in Fetal and Neonatal Alloimmune Thrombocytopenia: An Observational Study

2021 ◽  
Vol 22 (13) ◽  
pp. 6763
Author(s):  
Thijs W. de Vos ◽  
Dian Winkelhorst ◽  
Hans J. Baelde ◽  
Kyra L. Dijkstra ◽  
Rianne D. M. van Bergen ◽  
...  
Keyword(s):  
Complement Activation ◽  
Histopathological Examination ◽  
Hla Class I ◽  
Unknown Etiology ◽  
Low Grade ◽  
Classical Pathway ◽  
Newly Diagnosed ◽  
Activation Markers ◽  
Amsterdam Criteria ◽  
Alloimmune Thrombocytopenia

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a disease that causes thrombocytopenia and a risk of bleeding in the (unborn) child that result from maternal alloantibodies directed against fetal, paternally inherited, human platelet antigens (HPA). It is hypothesized that these alloantibodies can also bind to the placenta, causing placental damage. This study aims to explore signs of antibody-mediated placental damage in FNAIT. We performed a retrospective study that included pregnant women, their newborns, and placentas. It comprised 23 FNAIT cases, of which nine were newly diagnosed (14 samples) and 14 were antenatally treated with intravenous immune globulins (IVIg) (21 samples), and 20 controls, of which 10 had anti-HLA-class I antibodies. Clinical information was collected from medical records. Placental samples were stained for complement activation markers (C1q, C4d, SC5b-9, and mannose-binding lectin) using immunohistochemistry. Histopathology was examined according to the Amsterdam criteria. A higher degree of C4d deposition was present in the newly diagnosed FNAIT cases (10/14 samples), as compared to the IVIg-treated FNAIT cases (2/21 samples, p = 0.002) and anti-HLA-negative controls (3/20 samples, p = 0.006). A histopathological examination showed delayed maturation in four (44%) placentas in the newly diagnosed FNAIT cases, five (36%) in the IVIg-treated FNAIT cases, and one in the controls (NS). C4d deposition at the syncytiotrophoblast was present in combination with low-grade villitis of unknown etiology in three newly diagnosed FNAIT cases that were born SGA. We conclude that a higher degree of classical pathway-induced complement activation is present in placentas from pregnancies with untreated FNAIT. This may affect placental function and fetal growth.

scholarly journals Teaching NeuroImages: Isolated peripheral facial palsy due to ipsilateral pontine infarction

Neurology ◽  
2015 ◽  
Vol 85 (1) ◽  
pp. e1-e2 ◽  
Author(s):  
Seong-il Oh ◽  
Eung-Gyu Kim ◽  
Hae Woong Jeong ◽  
Sang Jin Kim
Keyword(s):  
Facial Palsy ◽  
Peripheral Facial Palsy ◽  
Pontine Infarction

Unusual cerebral venous thrombosis presenting with peripheral facial palsy: A case report

2013 ◽  
Vol 333 ◽  
pp. e269-e270
Author(s):  
A. Tufekci ◽  
S. Kirbas ◽  
S. Cakmak ◽  
A. Kirbas ◽  
A. Kanat
Keyword(s):  
Case Report ◽  
Venous Thrombosis ◽  
Facial Palsy ◽  
Cerebral Venous Thrombosis ◽  
Peripheral Facial Palsy

Recurrent bilateral peripheral facial palsy

1989 ◽  
Vol 103 (1) ◽  
pp. 117-119 ◽  
Author(s):  
N. Stahl ◽  
T. Ferit
Keyword(s):  
Facial Nerve ◽  
Facial Palsy ◽  
Common Finding ◽  
Facial Nerve Paralysis ◽  
Nerve Paralysis ◽  
Peripheral Facial Palsy ◽  
Local Disease ◽  
Idiopathic Facial Palsy

AbstractFacial nerve paralysis is a common otolaryngological diagnosis. Recurrent unilateral peripheral facial palsy is found in about 7 per cent of the cases. Simultaneous bilateral facial palsy is relatively uncommon and occurs in 0.3–2.0 per cent of cases of facial palsy. Recurrent. simultaneous, bilateral, idiopathic facial palsy to the best of our knowledge has never been reported. A case of recurrent, simultaneous, bilateral, idiopathic facial palsy is presented. No evidence of systemic or local disease was found in both attacks of peripheral facial palsies. The association with states of stress is the only common finding between the two attacks.

A Statistical Study of Peripheral Facial Palsy

1993 ◽  
Vol 1993 (Supplement61) ◽  
pp. 178-184
Author(s):  
Katsuhiko Nakamura ◽  
Yohji Hori ◽  
Atsushi Mabuchi ◽  
Kohji Kimoto ◽  
Yasuo Koike
Keyword(s):  
Facial Palsy ◽  
Statistical Study ◽  
Peripheral Facial Palsy

scholarly journals Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings

2014 ◽  
Vol 72 (7) ◽  
pp. 496-499 ◽  
Author(s):  
Ronaldo Lessa ◽  
Maurício Castillo ◽  
Renata Azevedo ◽  
Fernanda Azevedo ◽  
Hildo Azevedo
Keyword(s):  
Facial Palsy ◽  
H1n1 Virus ◽  
Altered Mental Status ◽  
H1n1 Influenza ◽  
Neurological Complications ◽  
Abrupt Onset ◽  
Resonance Imaging ◽  
Post Vaccination ◽  
Peripheral Facial Palsy ◽  
The Right

Objective: To report 4 different neurological complications of H1N1 virus vaccination. Method: Four patients (9, 16, 37 and 69 years of age) had neurological symptoms (intracranial hypertension, ataxia, left peripheral facial palsy of abrupt onset, altered mental status, myelitis) starting 4-15 days after H1N1 vaccination. MRI was obtained during the acute period. Results: One patient with high T2 signal in the cerebellum interpreted as acute cerebellitis; another, with left facial palsy, showed contrast enhancement within both internal auditory canals was present, however it was more important in the right side; one patient showed gyriform hyperintensities on FLAIR with sulcal effacement in the right fronto-parietal region; and the last one showed findings compatible with thoracic myelitis. Conclusion: H1N1 vaccination can result in important neurological complications probably secondary to post-vaccination inflammation. MRI detected abnormalities in all patients.

Borrelia burgdorferi sensu lato infection in patients with peripheral facial palsy

2019 ◽  
Vol 10 (2) ◽  
pp. 398-406
Author(s):  
Tereza Rojko ◽  
Petra Bogovič ◽  
Stanka Lotrič-Furlan ◽  
Katarina Ogrinc ◽  
Tjaša Cerar-Kišek ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Facial Palsy ◽  
Borrelia Burgdorferi Sensu Lato ◽  
Peripheral Facial Palsy

scholarly journals Surgical management of bronchopulmonary carcinoids: A single center experience

2017 ◽  
Vol 06 (01) ◽  
pp. 006-010 ◽  
Author(s):  
Ashish Jakhetiya ◽  
Pankaj Kumar Garg ◽  
Rambha Pandey ◽  
Palaniappan Ramanathan ◽  
Sunil Kumar ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Histopathological Examination ◽  
Postoperative Mortality ◽  
North India ◽  
Biological Behavior ◽  
Long Term Results ◽  
Surgical Approaches ◽  
Delayed Presentation ◽  
Duration Of Symptoms ◽  
Tertiary Teaching

Abstract Introduction: Bronchopulmonary carcinoids are uncommon tumors with relatively indolent biological behavior but a distinct malignant potential. Surgery is the mainstay of treatment. Our aim was to study preoperative characteristics, surgical approaches, and outcome in patients with bronchopulmonary carcinoid tumors. Patients and Methods: This retrospective study was done in the Department of Surgical Oncology of a Tertiary Teaching Hospital of North India. The case records of all the patients who underwent surgical treatment for lung neoplasms and were diagnosed to have bronchopulmonary carcinoids were reviewed. Details concerning the clinical presentation, preoperative therapy, operative procedure, postoperative complications, and outcome were retrieved from the case records. Results: Sixteen patients who underwent surgical treatment were found to have bronchopulmonary carcinoids on histopathological examination. The median age of the patients was 34 years (range 18–62 years). There were 11 men and five women. All patients were symptomatic, and the median duration of symptoms was 12 months (range 6–72 months) before presentation. Six patients had received antitubercular treatment before presentation, and one patient had been treated with chemotherapy due to misdiagnosis. Surgical procedures included six pneumonectomies (one with carinoplasty), four bilobectomies, three lobectomies, and three bronchoplastic procedures (two with lobectomy and one with bilobectomy). There was no postoperative mortality; three patients had morbidity in the form of lobar collapse, prolonged pleural collection, and surgical site infection. With a median follow-up time of 11 months (range 2–85 months), all the 16 patients are alive and disease-free. Conclusions: Delayed presentation and misdiagnosis of bronchial carcinoid are major concerns in North India. Adequate surgical resection can be performed without undue morbidity and is associated with good long-term results.

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