scholarly journals Analysis Mortality in Patients with HIV-infection on Example of a Region with a High Prevalence of Infection

2018 ◽  
Vol 17 (1) ◽  
pp. 40-47
Author(s):  
V. Ya. Rosenberg ◽  
Yu. K. Plotnikova ◽  
E. E. Voronin

RelevanceThe HIV epidemic, registered worldwide since the early 1980s, is currently continuing its development in most countries, and, according to the Joint United Nations Program on HIV/AIDS (UNAIDS, 2016), covers more than 36 million people (including 1.8 million children) AIDS mortality is a key indicator of the effectiveness of the response to the HIV epidemic. On the example of the Irkutsk region as a region with high lesion, an analysis of the main indicators and causes of death of patients with HIV infection was carried out.Goal– analysis of the mortality of HIV / AIDS patients by the example of a region with a high degree of defeat in order to determine the key criteria for evaluating activities to reduce the mortality from HIV/AIDS.Materials and methods An analysis was made of the causes of mortality of patients with HIV infection in the Irkutsk region in 2014– 2016, using comparative data of modern domestic and foreign literature (including total mortality), as well as accounting and reporting documentation of the Irkutsk Regional Center for prevention and control of AIDS and infectious diseases.Results 1.There is an increase in the death rate of HIV-infected people, including those caused by HIV. 2. The increase in mortality practically does not lead to an increase in mortality due to a parallel increase in the number of people living with HIV. 3. The main causes of death from HIV infection (AIDS) are pathologies with primary respiratory system damage: tuberculosis and pneumonia, which requires special attention in developing approaches to diagnosis, recording, treatment and prevention of these diseases, as well as assessing the impact of vaccination of patients with HIV infection against pneumococcus on mortality from pneumonia. 4. The increase in ART coverage of all patient populations contributes to the stabilization of mortality from HIV/AIDS.Conclusions:the most important for assessing the impact of ongoing efforts of the health system to reduce mortality among HIVinfected patients is the correct registration and diagnosis (including posthumous) of AIDS-indicative diseases, certainly associated with the progression of HIV infection. 

2019 ◽  
Vol 7 (20) ◽  
pp. 3459-3463
Author(s):  
Elmeida Effendy ◽  
Mustafa M. Amin ◽  
Lidya De Vega ◽  
Nurul Utami

BACKGROUND: The lives of individuals diagnosed with HIV and the subsequent illness, AIDS, were often chaotic because these individuals deal with the physical, emotional, and interpersonal sequelae of this illness. Depressive symptoms and stress were common and impact on functioning, quality of life, and health status, highlighting the importance of diagnosis and treatment of patients with HIV infection. Psychiatric clinical practice and rating scales have come to play an ever-increasing role both in determining specific symptoms and diagnosing an individual condition. Descriptive reports of psychiatric morbidity among those with HIV infection, that relied primarily on self-report rating scales, described high rates of symptomatic depression and stress. AIM: This study aimed to determine the proportion of depression among people living with HIV/AIDS using the BDI-II and PSS to determine a relationship between symptoms of depression and stress with CD4 counts. METHODS: This study was a numerical correlative analytic study with a cross-sectional study approach that assessed the correlation between stress, depression and CD4 level in people with HIV/AIDS that were receiving ARV therapy in the Voluntary Counselling Test (VCT) Polyclinic of General Hospital Haji Medan by recruiting 46 subjects. CD4 level was examined in the Pramita Medan laboratory. RESULTS: When analysis of BDI-II level and CD4 scores were done, a significant correlation was found (P < 0.05). The strength of the relationship between the BDI score and the CD4 score was 0.548 revealing a positive correlation with moderate correlation strength CONCLUSION: We have shown a significant relationship between depression, stress and CD4 level among people with HIV/AIDS in Medan, Indonesia. Psychological distress may affect the immunity in infected people, leading to the disease progressivity.


Religions ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 409 ◽  
Author(s):  
Song ◽  
Qin

Faith-based programs have been long regarded as influential social approaches to form positive attitudes to human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) within the last few decades. However, recent scholars argue that religions serve a double role in supporting HIV-infected people. Moreover, relevant evidence is mainly collected from studies among participants of the Western religious traditions, such as Christianity. This study applies the theory of the attitude formation model to examine Buddhist factors impacting discriminatory attitudes towards HIV/AIDS and the causal path to positive behavior intention. To investigate its underlying mechanism, Buddhist elements, as an important antecedent, were introduced in the advertisement against HIV/AIDS-related discrimination to influence people’s attitudinal reaction. Results show that Buddhist advertising could significantly increase perceived religiosity and compassion. Then, both perceived religiosity and compassion jointly increase anti-prejudical attitudes towards HIV-infected people and have a positive impact on interaction intention at the end.


2018 ◽  
Vol 4 (6) ◽  
pp. 559-565
Author(s):  
Putu Dian Prima Kusuma Dewi ◽  
Putu Sukma Megaputri ◽  
Lina Anggaraeni Dwijayanti ◽  
Dewa Ayu Putu Indra Pranita ◽  
Made Juniari Dewi

Background: Mortality in people living with HIV/AIDS is one of measures to the success of its treatment. Study related to their deaths seen from gender is still very limited.Objective: The aim of this study was to determine the incidence rate of mortality between men and women living with HIV/AIDS and receiving antiretroviral therapy.Methods: This was a retrospective study using secondary data of HIV/AIDS-infected patients in Buleleng District Hospital in the period of 2006-2015. This research used Survival analysis, Kaplan-meier, incident rate comparison and logistic regression with STATA SE 12.Results: A total of 1204 HIV/AIDS-infected patients data was included. The incidence of total mortality rates was 27.7 per 1000 person-years. Based on gender, the mortality in men (35 per 1000 person-years) was higher than women (14 per 1000 person-years) with the incidence rate ratio (IRR) of 2.39 (p 0.01).  Fifty percent of cases of mortality occured at 0.15 years of observation. The median time of mortality in men was 0.14 years (1.7 months) and in women was 0.15 years (1.8 months). The poor clinical condition was seen from a body weight <50 kg, which increased the risk of death with aOR 3.85 (p 0.01 CI 2.40-6.16). Nevirapine increased the risk of mortality (aOR 2.18; p 0.01; CI 1.18-4.03). and CD4 cell counts of ≤ 200 cells / mm3 reduced the risk of death by 69% (AOR 0.31; p 0.01; CI 0.18-0.53).Conclusion: The incidence of mortality in men was greater than it in women, which is caused by poor clinical conditions. It is better to evaluate the success of antiretroviral therapy by considering the needs of patients according to their gender. Further research is needed in regard to adherence of treatment and loss to follow-up events.


2021 ◽  
Author(s):  
Mohamed A Daw ◽  
Abdallah HU El-Bouzedi ◽  
Mohamed O Ahmed

ABSTRACT The interrelationships between HIV/AIDS and armed conflict are a complex phenomenon and studies are rarely devoted to this area of research. Libya is the second-largest country in Africa that has been evoked with war since NATO intervention in 2011. The country has also experienced one of the largest HIV outbreaks associated with the Bulgarian Nurses saga. The effect of the armed conflict on the dynamic spread of HIV is not well known. The objectives of this study were to determine the impact of armed conflict on the epidemiological situation of HIV infection in Libya and analyze the transmission dynamics of HIV strains during the conflict. We investigated the movement of HIV-infected people during the Libyan armed conflict and analyzed the HIV subtypes reported from 2011 to 2020 and followed up the infected cases all over the country. The patterns of HIV spread within the Libyan regions were traced and risk factors were determined during the conflict period. A total of 4539 HIV/AIDS patients were studied from the four regions during the Libyan conflict. Our data analysis indicated that Benghazi the biggest city in the Eastern region was the significant exporter of the virus to the rest of the country. Viral dissemination changes were observed within the country particularly after 2015. A major virus- flow from the Eastern region during the armed conflict associated with internally displaced people. This resulted in a dissemination of new HIV strains and accumulations of HIV cases in Western and Meddle regions. Although, there were no significant changes in the national prevalence of HIV/AIDS. Our data highlights the factors that complicated the spread and dissemination of HIV during the armed conflict which provides a better understanding of the interaction between them. This could be used to plan for effective preventive measures in tackling the spread of HIV in conflict and post-conflict settings.


2019 ◽  
Vol 15 (4) ◽  
pp. 106-116
Author(s):  
Aleksandr Kuklin ◽  
Andrey Tsvetkov ◽  
Dar’ya Ypaneshnikova ◽  
I . KOROBKOV

The Object of the Study. The territory of the Ural Federal Okrug with HIV infection spread.The Subject of the Study. The socioeconomic relations between the executive and the health system at all levels that arises about the fixation, diagnosis, prevention of HIV infection The Purpose of the Study is critical diagnosing the state of the territory to predict the number of able-bodied population of the region, taking into account socially significant medical factors (incidence of HIV infection).The Main Provisions of the Article. Fertility decline, population aging, mortality have a directly impact on the demographic situation in the Urals Federal Okrug. Population projections are taking into account different socio-economic trends should precede the development of demographic policies. Currently, in most subjects of the Ural Federal Okrug, the number of elderly people is increasing, the number of people of working age is decreasing and, accordingly, the demographic load on the working population is increasing. In the framework of this study, the calculation of demographic security of the Ural Federal Okrug and a model of the influence of various socio-economic factors on it is proposed. It is shown that the level of demographic security for a number of regions included in the Ural Federal Okrug began to decline in 2015 and strive to get out of the normal state. On the basis of the offered model one of the factors influencing demographic safety – HIV infection and AIDS is chosen. The calculation of the medical and demographic forecast of the able-bodied population, are taking into account the impact of HIV infection. Sverdlovsk and Chelyabinsk Regions are among the leaders in the number of HIV-infected people, in some regions we are talking about an epidemic. This disease is characterized by a long latent period, the defeat, mainly young people of working age, the high cost of treatment, the lack of reliable methods of treatment and vaccination. The mathematical model allowing to consider influence of HIV infection on change of population of working age is constructed, calculations for Sverdlovsk, Chelyabinsk and Kurgan Regions have been carried out. Comparison of forecast values with and without adjustment for HIV/AIDS factors shows a significant impact of the disease on the demographic picture of the Sverdlovsk and Chelyabinsk Regions.


2021 ◽  
Author(s):  
Mohamed Ali DAW ◽  
Abdallah Hussean El-Bouzedi ◽  
Mohamed Omar Ahmed

Abstract The interrelationships between HIV/AIDS and armed conflict are a complex phenomenon and studies are rarely devoted to this area of research. Libya is the second-largest country in Africa that has been evoked with war since NATO intervention in 2011. The country has also experienced one of the largest HIV outbreaks associated with the Bulgarian Nurses saga. The effect of the armed conflict on the dynamic spread of HIV is not well known. The objectives of this study were to determine the impact of armed conflict on the epidemiological situation of HIV infection in Libya and analyze the transmission dynamics of HIV strains during the conflict. We investigated the movement of HIV-infected people during the Libyan armed conflict and analyzed the HIV subtypes reported from 2011 to 2020 and followed up the infected cases all over the country. The patterns of HIV spread within the Libyan regions were traced and risk factors were determined during the conflict period. A total of 4539 HIV/AIDS patients were studied from the four regions during the Libyan conflict. Our data analysis indicated that Benghazi the biggest city in the Eastern region was the significant exporter of the virus to the rest of the country. Viral dissemination changes were observed within the country particularly after 2015. A major virus- flow from the Eastern region during the armed conflict associated with internally displaced people. This resulted in a dissemination of new HIV strains and accumulations of HIV cases in Western and Meddle regions. Although, there were no significant changes in the national prevalence of HIV/AIDS. Our data highlights the factors that complicated the spread and dissemination of HIV during the armed conflict which provides a better understanding of the interaction between them. This could be used to plan for effective preventive measures in tackling the spread of HIV in conflict and post-conflict settings.


2020 ◽  
pp. 095646242095298
Author(s):  
Augusto Cesar Lara de Sousa ◽  
Tatiana de Araujo Eleuterio ◽  
José Victor Afonso Coutinho ◽  
Raphael Mendonça Guimarães

To describe the trends of HIV/AIDS metrics related to the burden of disease for Brazil between 1990 and 2017 we conducted a timeseries analysis for HIV/AIDS indicators by extracting data from the Global Burden of Disease study. We calculated traditional prevalence, incidence and mortality rates, the number of years lost by HIV-related deaths (YLL) and disability (YLD), and disability-adjusted life years (DALY). We estimated time series models and assessed the impact of highly active antiretroviral therapy (HAART) on the same indicators. In the set of disability-adjusted life years (DALY), the highest weight of its magnitude was due to YLL. There was a decline, especially after 1996, of DALY, mortality and YLL for HIV/AIDS. However, YLD, incidence, and prevalence increased over the same period. Also, the analysis of interrupted time series showed that the introduction of HAART into health policy had a significant impact on indicators, especially for DALY and YLL. We need to assess the quality of life of people living with HIV, especially among older adults. In addition, we need to focus on primary prevention, emphasizing methods to avoid infection and public policies should reflect this.


2016 ◽  
Vol 21 (3) ◽  
pp. 766-782 ◽  
Author(s):  
John A. Maluccio ◽  
Fan Wu ◽  
Redwan B. Rokon ◽  
Rahul Rawat ◽  
Suneetha Kadiyala

2009 ◽  
Vol 17 (04) ◽  
pp. 685-712 ◽  
Author(s):  
G. THOMAS ◽  
E. M. LUNGU

The Sub-Sahara African region is inhabited by only 11% of the global population, but is home to 67% of the total HIV infected people and accounts for more than 70% of global AIDS deaths. In this study, we construct a mathematical model to investigate the effect of heavy alcohol consumption on the transmission and progression of HIV/AIDS, and to assess the impact of heavy drinkers on HIV/AIDS related social and health problems such as TB case load and number of orphans. Using demographic data for Botswana, we have shown that if more HIV/AIDS individuals had been de-addicted from heavy alcohol consumption, the severity of the HIV/AIDS epidemic and the impact of HIV/AIDS on the number of TB cases and orphans would have been significantly less than is the case currently. The study points to the vital need for counseling and education about the evils of heavy alcohol consumption and for alcohol de-addiction programmes.


Sign in / Sign up

Export Citation Format

Share Document