THE INFLUENCE OF HEAVY ALCOHOL CONSUMPTION ON HIV INFECTION AND PROGRESSION

The Sub-Sahara African region is inhabited by only 11% of the global population, but is home to 67% of the total HIV infected people and accounts for more than 70% of global AIDS deaths. In this study, we construct a mathematical model to investigate the effect of heavy alcohol consumption on the transmission and progression of HIV/AIDS, and to assess the impact of heavy drinkers on HIV/AIDS related social and health problems such as TB case load and number of orphans. Using demographic data for Botswana, we have shown that if more HIV/AIDS individuals had been de-addicted from heavy alcohol consumption, the severity of the HIV/AIDS epidemic and the impact of HIV/AIDS on the number of TB cases and orphans would have been significantly less than is the case currently. The study points to the vital need for counseling and education about the evils of heavy alcohol consumption and for alcohol de-addiction programmes.

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A two-sex model for the influence of heavy alcohol consumption on the spread of HIV/AIDS

Mathematical Biosciences and Engineering ◽

10.3934/mbe.2010.7.871 ◽

2010 ◽

Vol 7 (4) ◽

pp. 871-904 ◽

Cited By ~ 5

Keyword(s):

Alcohol Consumption ◽

Heavy Alcohol ◽

Heavy Alcohol Consumption ◽

Hiv Aids

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The impact of long-term moderate and heavy alcohol consumption on incident atherosclerosis among persons living with HIV

Drug and Alcohol Dependence ◽

10.1016/j.drugalcdep.2017.09.034 ◽

2017 ◽

Vol 181 ◽

pp. 235-241 ◽

Cited By ~ 4

Author(s):

N.E. Kelso-Chichetto ◽

M. Plankey ◽

D.S. Sheps ◽

A.G. Abraham ◽

X. Chen ◽

...

Keyword(s):

Alcohol Consumption ◽

Heavy Alcohol ◽

Persons Living With Hiv ◽

Heavy Alcohol Consumption ◽

Living With Hiv ◽

The Impact

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Sleep after Heavy Alcohol Consumption and Physical Activity Levels during Alcohol Hangover

Journal of Clinical Medicine ◽

10.3390/jcm8050752 ◽

2019 ◽

Vol 8 (5) ◽

pp. 752 ◽

Cited By ~ 14

Author(s):

Lydia E. Devenney ◽

Kieran B. Coyle ◽

Thomas Roth ◽

Joris C. Verster

Keyword(s):

Alcohol Consumption ◽

Sleep Quality ◽

Real Time ◽

Alcoholic Beverages ◽

Activity Levels ◽

Heavy Alcohol ◽

Subjective Assessments ◽

Heavy Alcohol Consumption ◽

Alcohol Hangover ◽

The Impact

Alcohol consumption can negatively affect sleep quality. The current study examined the impact of an evening of alcohol consumption on sleep, and next day activity levels and alcohol hangover. n = 25 healthy social drinkers participated in a naturalistic study, consisting of an alcohol and alcohol-free test day. On both days, a GENEactiv watch recorded sleep and wake, and corresponding activity levels. In addition, subjective assessments of sleep duration and quality were made, and hangover severity, and the amount of consumed alcoholic beverages were assessed. Alcohol consumption was also assessed in real-time during the drinking session, using smartphone technology. The results confirmed, by using both objective and subjective assessments, that consuming a large amount of alcohol has a negative impact on sleep, including a significant reduction in objective sleep efficiency and significantly lower self-reported sleep quality. Activity levels during the hangover day were significantly reduced compared to the alcohol-free control day. Of note, next-morning retrospective alcohol consumption assessments underestimated real-time beverage recordings. In conclusion, heavy alcohol consumption impairs sleep quality, which is associated with increased next day hangover severity and reduced activity levels. The outcome of this study underlines that, in addition to retrospectively reported data, real-time objective assessments are needed to fully understand the effects of heavy drinking.

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Heavy Drinking Habits Are Associated with Worse In-Hospital Outcomes in Patients with Acute Coronary Syndrome: An Insight from the AMIS Plus Registry

Cardiology ◽

10.1159/000508928 ◽

2020 ◽

Vol 145 (12) ◽

pp. 757-765

Author(s):

Gregorio Tersalvi ◽

Luigi Biasco ◽

Dragana Radovanovic ◽

Hans Rickli ◽

Marco Roffi ◽

...

Keyword(s):

Alcohol Consumption ◽

Hospital Mortality ◽

Alcohol Intake ◽

Hospital Outcomes ◽

Heavy Alcohol ◽

Coronary Syndrome ◽

Daily Alcohol Intake ◽

Heavy Alcohol Consumption ◽

The Impact ◽

Regular Alcohol Consumption

Background: The association between alcohol consumption and the occurrence of coronary heart disease is well described in the literature, while data regarding the impact of regular alcohol consumption on in-hospital outcomes in the setting of acute coronary syndrome (ACS) are lacking. We aimed to evaluate the impact of self-reported alcohol consumption on in-hospital outcomes in patients with ACS. Methods: Data derived from patients enrolled between 2007 and 2019 in the Acute Myocardial Infarction in Switzerland (AMIS) Plus registry were retrospectively analyzed. Patients were stratified based on alcohol drinking pattern. Primary outcome was all-cause in-hospital mortality, while secondary outcomes were set as incidence of major adverse cardiac and cerebrovascular events (MACCEs). Outcome comparisons according to quantity of daily alcohol intake were also performed. Results: Records concerning alcohol consumption were available in 25,707 patients; 5,298 of them (21%) fulfilled the criteria of regular alcohol consumption. Regular drinkers were predominantly male, younger, smokers, more comorbid and with a worse clinical presentation as compared with abstainers/occasional drinkers. Daily alcohol intake was reported in 4,059 (77%) of these patients (regular drinkers). Among them, 2,640 were light drinkers (≤2 drinks/day) and 1,419 heavy drinkers (>2 drinks/day). In-hospital mortality and MACCEs of heavy drinkers were significantly higher compared with those of light drinkers (5.4 vs. 3.3% and 7.0 vs. 4.4%, both p = 0.001). When tested together with Global Registry of Acute Coronary Events risk score parameters, heavy alcohol consumption was independently associated with in-hospital mortality (p = 0.004). Conclusions: Our results support that heavy alcohol consumption is an independent predictor of in-hospital mortality in patients presenting with ACS.

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Stigma, Discrimination, and Ostracization: HIV/AIDS Infection in Nigeria

International Quarterly of Community Health Education ◽

10.2190/ll7f-03vg-3qat-r6p9 ◽

2003 ◽

Vol 22 (1) ◽

pp. 125-129 ◽

Cited By ~ 2

Author(s):

Adesola O. Oyelese

Keyword(s):

Health Professionals ◽

Acquired Immunodeficiency Syndrome ◽

Sex Workers ◽

Infected People ◽

Aids Epidemic ◽

Major Constraint ◽

Acquired Immunodeficiency ◽

Immunodeficiency Syndrome ◽

And Control ◽

Hiv Aids

The AIDS epidemic continues and HIV-infected persons continue to suffer stigmatization and discrimination in Nigeria. The results of an open-ended questionnaire administered non-randomly in Ile-Ife and Ilesa in the late 1990s confirm this. Six questions on Acquired Immunodeficiency Syndrome (AIDS) were asked; 83 (36.4%) males and 145 (63.6%) females aged between 11 and 60 years responded. The respondents included 101 students, 49 civil servants, 39 artisans and traders. Others included 29 health professionals (doctors and nurses, etc.), 8 teachers, and 2 commercial sex workers. The median of negative responses (rejection) is 42.2%. It is concluded that there still exists a significant but suppressed or subtle stigmatization and discrimination against HIV-infected people, a major constraint in the management and control of HIV/AIDS.

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Coronary deaths during Midsummer festival in Finland: miseries of long, light nights

European Journal of Epidemiology ◽

10.1007/s10654-021-00744-6 ◽

2021 ◽

Author(s):

Simo Näyhä

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Alcohol Consumption ◽

Negative Binomial ◽

Negative Binomial Regression ◽

Adverse Consequence ◽

Heavy Alcohol ◽

Summer Peak ◽

Binomial Regression ◽

Heavy Alcohol Consumption

AbstractThis paper examines whether the anomalous summer peak in deaths from coronary heart disease (CHD) in Finland could be attributed to adverse effects of the Midsummer festival and alcohol consumption during the festival. Daily deaths from CHD and alcohol poisoning in Finland, 1961–2014, that occurred during the 7 days centering on Midsummer Day were analysed in relation to deaths during 14 to 4 days before and 4 to 14 after Midsummer Day. Daily counts of deaths from CHD among persons aged 35–64 years were regressed on days around the Midsummer period by negative binomial regression. Mortality from CHD was highest on Midsummer Day (RR 1.25 (95% confidence interval 1.12–1.31), one day after the peak in deaths from alcohol poisonings. RR for CHD on Midsummer Day was particulary high (RR = 1.43; 1.09–1.86) in the 2000s, 30% of deaths being attributable to that day. In conclusion, the anomalous and prominent summer peak in deaths from CHD in Finland is an adverse consequence of the Midsummer festival. The most likely underlying reason is heavy alcohol consumption during the festival period, especially on Midsummer Eve. In the 2000s, one third of deaths from CHD on Midsummer Day are preventable.

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Current Heavy Alcohol Consumption is Associated with Greater Cognitive Impairment in Older Adults

Alcoholism Clinical and Experimental Research ◽

10.1111/acer.13211 ◽

2016 ◽

Vol 40 (11) ◽

pp. 2435-2444 ◽

Cited By ~ 33

Author(s):

Adam J. Woods ◽

Eric C. Porges ◽

Vaughn E. Bryant ◽

Talia Seider ◽

Assawin Gongvatana ◽

...

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Alcohol Consumption ◽

Heavy Alcohol ◽

Heavy Alcohol Consumption

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Abstract P002: Heavy Alcohol Consumption Increases the Risk of Atrial Fibrillation -Circulatory Risk in Communities Study(CIRCS)

Circulation ◽

10.1161/circ.127.suppl_12.ap002 ◽

2013 ◽

Vol 127 (suppl_12) ◽

Author(s):

Fumihiko Sano ◽

Tetsuya Ohira ◽

Akihiko Kitamura ◽

Hironori Imano ◽

Renzhe Cui ◽

...

Keyword(s):

Atrial Fibrillation ◽

Alcohol Consumption ◽

Medical History ◽

Moderate Alcohol Consumption ◽

Heavy Alcohol ◽

Ethanol Drinking ◽

Wide Range ◽

Detailed Medical History ◽

Heavy Alcohol Consumption

Background— Evidence on the relationship of a wide range of alcohol consumption with risk of incident atrial fibrillation has been limited. Methods— Between 1991 and 1995, 8602 Japanese men and women aged 30 to 80 years and free of clinical atrial fibrillation took part in the first examination of the Circulatory Risk in Communities Study(CIRCS)- a population based cohort study of cardiovascular risk factors, cardiovascular disease incidence, and their trends in Japanese communities. In the first examination, we checked a detailed medical history, physical examination, blood and urine examination, and electrocardiogram (ECG). An interviewer obtained histories in detail for weekly alcohol intake. In the follow-up period, incident atrial fibrillations were ascertained by annual ECG record and medical history of treatment of atrial fibrillation. ECGs were coded with the Minnesota Code by trained physician-epidemiologists. Differences in baseline characteristics between atrial fibrillation cases and controls were compared using Student t-tests or chi-squared tests. The hazard ratios (HRs) of incidence of atrial fibrillation and 95% confidence interval (CI) relative to the never-drinking group were calculated with adjustment for age and other potential confounding factors using the Cox proportional hazard model. Results— During an average follow-up of 6.4 years, 290 incident atrial fibrillation occurred. The higher incidence rate of atrial fibrillation was observed among participants with more than 69 g of ethanol drinking per week, compared with less than 69 g of ethanol drinking per week. On the other hand, light to moderate alcohol consumption was not associated with risk of atrial fibrillation. Compared with the never drinking group, the multivariable-adjusted HRs of past, light (<23 g), light moderate (23-46 g), moderate (46-69 g), and heavy (>69 g) drinking groups were 1.20 (95% CI, 0.61-2.35), 0.85 (95% CI, 0.57-1.27), 1.05 (95% CI, 0.63-1.75), 1.34 (95% CI, 0.78-2.32), and 2.92 (95% CI, 1.61-5.28), respectively. Conclusions— Heavy alcohol consumption was associated with the higher risk of atrial fibrillation, whereas there was no association of less than moderate alcohol consumption and atrial fibrillation.

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