Effects of Saccharomyces cerevisiae fermentation products on dairy calves: Performance and health

Abstract The objectives of this study were to determine the effects of oral supplementation with Saccharomyces cerevisiae fermentation products (SCFP; SmartCare and NutriTek; Diamond V, Cedar Rapids, IA) on immune function and bovine respiratory syncytial virus (BRSV) infection in preweaned dairy calves. Twenty-four Holstein × Angus, 1- to 2-d-old calves (38.46 ± 0.91 kg initial body weight [BW]) were assigned two treatment groups: control or SCFP treated, milk replacer with 1 g/d SCFP (SmartCare) and calf starter top-dressed with 5 g/d SCFP (NutriTek). The study consisted of one 31-d period. On days 19 to 21 of the supplementation period, calves were challenged via aerosol inoculation with BRSV strain 375. Calves were monitored twice daily for clinical signs, including rectal temperature, cough, nasal and ocular discharge, respiration effort, and lung auscultation. Calves were euthanized on day 10 postinfection (days 29 to 31 of the supplementation period) to evaluate gross lung pathology and pathogen load. Supplementation with SCFP did not affect BW (P = 0.762) or average daily gain (P = 0.750), percentages of circulating white blood cells (P < 0.05), phagocytic (P = 0.427 for neutrophils and P = 0.460 for monocytes) or respiratory burst (P = 0.119 for neutrophils and P = 0.414 for monocytes) activity by circulating leukocytes either before or following BRSV infection, or serum cortisol concentrations (P = 0.321) after BRSV infection. Calves receiving SCFP had reduced clinical disease scores compared with control calves (P = 0.030), reduced airway neutrophil recruitment (P < 0.002), reduced lung pathology (P = 0.031), and a reduced incidence of secondary bacterial infection. Calves receiving SCFP shed reduced virus compared with control calves (P = 0.049) and tended toward lower viral loads in the lungs (P = 0.051). Immune cells from the peripheral blood of SCFP-treated calves produced increased (P < 0.05) quantities of interleukin (IL)-6 and tumor necrosis factor-alpha in response to toll-like receptor stimulation, while cells from the bronchoalveolar lavage (BAL) of SCFP-treated calves secreted less (P < 0.05) proinflammatory cytokines in response to the same stimuli. Treatment with SCFP had no effect on virus-specific T cell responses in the blood but resulted in reduced (P = 0.045) virus-specific IL-17 secretion by T cells in the BAL. Supplementing with SCFP modulates both systemic and mucosal immune responses and may improve the outcome of an acute respiratory viral infection in preweaned dairy calves.

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Effects of feeding Saccharomyces cerevisiae fermentation products on the health of Holstein dairy calves following a lipopolysaccharide challenge

Journal of Dairy Science ◽

10.3168/jds.2021-20341 ◽

2021 ◽

Author(s):

Rebecca N. Klopp ◽

Ilkyu Yoon ◽

Susan Eicher ◽

Jacquelyn P. Boerman

Keyword(s):

Saccharomyces Cerevisiae ◽

Dairy Calves ◽

Fermentation Products ◽

Lipopolysaccharide Challenge

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Effects of Saccharomyces cerevisiae fermentation products on dairy calves: Ruminal fermentation, gastrointestinal morphology, and microbial community

Journal of Dairy Science ◽

10.3168/jds.2015-10563 ◽

2016 ◽

Vol 99 (7) ◽

pp. 5401-5412 ◽

Cited By ~ 28

Author(s):

J.X. Xiao ◽

G.M. Alugongo ◽

R. Chung ◽

S.Z. Dong ◽

S.L. Li ◽

...

Keyword(s):

Saccharomyces Cerevisiae ◽

Microbial Community ◽

Dairy Calves ◽

Ruminal Fermentation ◽

Fermentation Products

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Amelioration of salmonellosis in pre-weaned dairy calves fed Saccharomyces cerevisiae fermentation products in feed and milk replacer

Veterinary Microbiology ◽

10.1016/j.vetmic.2014.05.026 ◽

2014 ◽

Vol 172 (1-2) ◽

pp. 248-255 ◽

Cited By ~ 24

Author(s):

Matthew T. Brewer ◽

Kristi L. Anderson ◽

Ilkyu Yoon ◽

Mark F. Scott ◽

Steve A. Carlson

Keyword(s):

Saccharomyces Cerevisiae ◽

Dairy Calves ◽

Milk Replacer ◽

Fermentation Products

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Saccharomyces cerevisiae Fermentation of 28 Barley and 12 Oat Cultivars

Fermentation ◽

10.3390/fermentation7020059 ◽

2021 ◽

Vol 7 (2) ◽

pp. 59

Author(s):

Timothy J. Tse ◽

Daniel J. Wiens ◽

Jianheng Shen ◽

Aaron D. Beattie ◽

Martin J. T. Reaney

Keyword(s):

Saccharomyces Cerevisiae ◽

Acetic Acid ◽

Lactic Acid ◽

Succinic Acid ◽

Alcoholic Fermentation ◽

Ethanol Yield ◽

Cereal Crops ◽

Fermentation Products ◽

Barley Cultivars ◽

Oat Cultivars

As barley and oat production have recently increased in Canada, it has become prudent to investigate these cereal crops as potential feedstocks for alcoholic fermentation. Ethanol and other coproduct yields can vary substantially among fermented feedstocks, which currently consist primarily of wheat and corn. In this study, the liquified mash of milled grains from 28 barley (hulled and hull-less) and 12 oat cultivars were fermented with Saccharomyces cerevisiae to determine concentrations of fermentation products (ethanol, isopropanol, acetic acid, lactic acid, succinic acid, α-glycerylphosphorylcholine (α-GPC), and glycerol). On average, the fermentation of barley produced significantly higher amounts of ethanol, isopropanol, acetic acid, succinic acid, α-GPC, and glycerol than that of oats. The best performing barley cultivars were able to produce up to 78.48 g/L (CDC Clear) ethanol and 1.81 g/L α-GPC (CDC Cowboy). Furthermore, the presence of milled hulls did not impact ethanol yield amongst barley cultivars. Due to its superior ethanol yield compared to oats, barley is a suitable feedstock for ethanol production. In addition, the accumulation of α-GPC could add considerable value to the fermentation of these cereal crops.

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PSIII-13 Effects of Saccharomyces Cerevisiae Fermentation Products on Lactating Sow Performance

Journal of Animal Science ◽

10.1093/jas/skab054.290 ◽

2021 ◽

Vol 99 (Supplement_1) ◽

pp. 172-172

Author(s):

Ricardo M Garcia ◽

Morgan T Thayer ◽

Kayla M Mills ◽

Jacob A Richert ◽

Katharine G Sharp ◽

...

Keyword(s):

Saccharomyces Cerevisiae ◽

Water Intake ◽

Feed Intake ◽

Control Diet ◽

Feed Additives ◽

Intermediate Water ◽

Lactation Period ◽

Fermentation Products ◽

Once Daily ◽

Lactating Sows

Abstract Lactating sows (N=140, York x Landrace) were used to evaluate the effects of a liquid prototype (LIQP) and dry (XPC®; Diamond V) Saccharomyces cerevisiae feed additives on sow and litter performance. Sows were fed a common gestation diet (0.55% SID-Lysine) until d112 of pregnancy and then allotted to lactation treatments: 1) Control diet (CON; 1.00% SID-Lysine), 2) CON +15 mL of LIQP from d112 to weaning (LIQ), 3) CON +0.20% of XPC from d112 to weaning (DRY), and 4) DRY +15 mL of LIQP from d112 to d7 post-farrowing (D+L). The LIQP was given once daily using an oral dose gun and XPC was included in the feed. Immunoglobulin concentrations were estimated on colostrum samples using Brix refractometer and piglet d 1 serum immunocrit ratio and plasma IgA and IgG. Daily sow water intake and daily feed intake (DFI) from d112 of gestation to d7 post-farrowing and weekly feed intake (ADFI) were recorded. There were no treatment effects on sow BW, backfat, or loin depth (P >0.05) although sows from LIQ group had numerically smaller BW reductions compared to CON sows (4.9% vs 7.2%, P=0.19). LIQ sows had greater DFI and CON lower DFI during week 1 of lactation (P=0.04) as well as ADFI for weeks 2, 3, and overall lactation period (P< 0.01) with DRY and D+L sows being intermediate. Water intake, immunoglobulins, and litter performance did not differ among treatments (P >0.05) although pigs from LIQ sows, compared to CON, had numerically increased weaning (6.14 vs 5.82kg, P >0.05) and litter weights (63.2 vs 60.1kg, P >0.05). LIQ sows had 0.7 d reduced wean-to-estrus interval (P< 0.001) and tended to have greater conception rates (P=0.07). In conclusion, LIQ supplementation of lactating sows improves feed intake, allowing sows to keep body reserves, and have better subsequent rebreeding performance.

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