Cerebrospinal fluid shunt infection due to Gemella haemolysans

2013 ◽  
Vol 11 (2) ◽  
pp. 205-209 ◽  
Author(s):  
William B. Lo ◽  
Mitul Patel ◽  
Guirish A. Solanki ◽  
Anthony Richard Walsh

Gemella haemolysans has long been considered a commensal in the human upper respiratory tract. Commensals are natural inhabitants on or within another organism, deriving benefit without harming or benefiting the host. Opportunistic infection of the CNS by the species is exceedingly rare. In the present case, a 16-year-old boy was admitted with a ventriculoperitoneal shunt infection, which was confirmed to be due to G. haemolysans. Following antibiotic treatment, removal of the old shunt, and delayed insertion of a new shunt, the patient made a full neurological recovery. To the authors' knowledge, this is the eighth case of CNS infection with G. haemolysans. Although prosthesis-related infections have been reported in other systems, this is the first case of CNS infection by the bacterium associated with an implant. Previous reported cases of CNS infection by G. haemolysans are reviewed. Due to the variable Gram staining property of the organism, the difficulty in diagnosing G. haemolysans infection is emphasized.

Author(s):  
Renan Domingues ◽  
Maria Cássia Mendes-Correa ◽  
Fernando Brunale Vilela de Moura Leite ◽  
Ester Cerdeira Sabino ◽  
Ingra M Claro ◽  
...  

Abstract The association between coronaviruses and central nervous system (CNS) demyelinating lesions has been previously shown. However, no case has been described of an association between the novel coronavirus (SARS-COV-2) and CNS demyelinating disease so far. SARS-COV-2 was previously detected in cerebrospinal fluid (CSF) sample of a patient with encephalitis. However, the virus identity was not confirmed by deep sequencing of SARS-COV-2 detected in the CSF. Here, we report a case of a patient with mild respiratory symptoms and neurological manifestations compatible with Clinically Isolated Syndrome. The viral genome of SARS-COV-2 was detected and sequenced in CSF with 99.74 to 100% similarity between the patient virus and worldwide sequences. This report suggests a possible association of SARS COV-2 infection with neurological symptoms of demyelinating disease, even in the absence of relevant upper respiratory tract infection signs.


PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e83229 ◽  
Author(s):  
Tamara D. Simon ◽  
Christopher E. Pope ◽  
Samuel R. Browd ◽  
Jeffrey G. Ojemann ◽  
Jay Riva-Cambrin ◽  
...  

1989 ◽  
Vol 15 (3) ◽  
pp. 131-135 ◽  
Author(s):  
Steven J. Schiff ◽  
Jerry Oakes

Brain Injury ◽  
2014 ◽  
Vol 28 (9) ◽  
pp. 1223-1225 ◽  
Author(s):  
Flávio Key Miura ◽  
Almir Ferreira Andrade ◽  
Bruno Azevedo Randi ◽  
Valdir Sabbaga Amato ◽  
Antonio Carlos Nicodemo

2021 ◽  
pp. 1-2
Author(s):  
Ali Ramadan ◽  
◽  
Abiye Kassa ◽  
◽  

Extramedullary (extraosseous) plasmacytoma represents a rare disease that accounts for less 5% of plasma cell neoplasms. It commonly occurs in the upper respiratory tract, with 80% of cases involving the paranasal sinuses, nasopharynx, or nasal cavity. Plasmacytomas of the eyelid are very rare with only ten cases having been reported in the literature so far. We present the clinical and histopathologic findings from a case of plasmacytoma of the eyelid and discuss its histopathologic differential diagnoses. To our knowledge, this is the first case of plasmacytoma of the eyelid in an HIV-positive patient in the English literature


Author(s):  
David C. Schulz ◽  
Sachin K. Pandey ◽  
Lulu L.C.D. Bursztyn

N-methyl-D-aspartate receptor (NMDA) encephalitis is a recently described autoimmune disease that typically presents with prodromal symptoms including upper respiratory tract infection, headache, fever, nausea, vomiting and diarrhea. Psychiatric symptoms follow within weeks, including anxiety, insomnia, mania, paranoia and grandiose delusions. The diagnosis is confirmed by the detection of NMDA antibodies in the serum or cerebrospinal fluid (CSF).1 Tumours, especially teratomas, are frequently associated with NMDA encephalitis; however, only 5% of male patients older than 18 years have been found to have an underlying tumour. Optic neuropathy associated with NMDA encephalitis is being increasingly recognised in the literature2–6 and was reviewed most recently by Mugavin et al.2 in 2017. In this report, we present a case of bilateral optic neuropathy in a young man diagnosed with NMDA receptor encephalitis.


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