Magnetic resonance image evaluation of pallidotomy lesions: a volumetric and shape analysis

Determination of acute pallidotomy-produced lesion volumes, pre- and postpallidotomy globus pallidus (GP) volumes, and assessment of lesion shape using magnetic resonance (MR) imaging-based computerized segmentation (contouring) and three-dimensional rendering was made in 19 patients. Magnetic resonance image slice thickness (1.5 mm or 6 mm) was not found to be a significant factor influencing contour-based pallidotomy lesion volume estimates. Previously reported lesion volumes produced by pallidotomy have often been estimated using the ellipsoid volume formula. Using 1.5-mm-thick MR sections, contour-based pallidotomy-produced lesion volumes were significantly different from those volumes estimated by the ellipsoid formula. Globus pallidus volumes, estimated by contouring T2-weighted MR images, were bilaterally similar (2.4 ± 0.37 ml [right]; 2.2 ± 0.45 ml [left]). Postoperative GP volumes were found on the contralateral, unlesioned side to be 2 ± 0.45 ml and on the lesioned side to be 1.25 ± 0.45 ml. Using the contralateral, unlesioned side as a reference volume, approximately 39 ± 14% of the GP was visibly affected on the lesioned side. Seventeen of 18 patients had a favorable outcome with reduced dyskinesias and "off" time with improvement in parkinsonian symptoms. Analysis of computerized three-dimensional rendering of pallidotomy-produced lesions based on MR images showed no relationship between lesioning technique and resulting lesion shape. Important factors in the volumetric analysis of pallidotomy lesions are identified and allow reasonable assessment of the pallidotomy lesion volume and shape and the extent of the affected GP.

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Open Source Applications for Image Visualization and Processing in Neuroimaging Training

Human-Computer Interaction ◽

10.4018/978-1-4666-8789-9.ch064 ◽

2015 ◽

pp. 1319-1332

Author(s):

Juan A. Juanes ◽

Pablo Ruisoto ◽

Alberto Prats-Galino ◽

Andrés Framiñán

Keyword(s):

Magnetic Resonance ◽

Medical Imaging ◽

Open Source ◽

Medical Images ◽

Three Dimensional ◽

Mr Images ◽

Image Visualization ◽

3D Slicer ◽

Volumetric Reconstruction ◽

Key Features

The aim of this paper is to demonstrate the major role and potential of three of the most powerful open source computerized tools for the advanced processing of medical images, in the study of neuroanatomy. DICOM images were acquired with radiodiagnostic equipment using 1.5 Tesla Magnetic Resonance (MR) images. Images were further processed using the following applications: first, OsiriXTM version 4.0 32 bits for OS; Second, 3D Slicer version 4.3; and finally, MRIcron, version 6. Advanced neuroimaging processing requires two key features: segmentation and three-dimensional or volumetric reconstruction. Examples of identification and reconstruction of some of the most complex neuroimaging elements such vascular ones and tractographies are included in this paper. The three selected applications represent some of the most versatile technologies within the field of medical imaging.

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A LARGE NEURINOMA ORIGINATING FROM THE ANTERIOR INTEROSSEOUS NERVE

Hand Surgery ◽

10.1142/s0218810412720355 ◽

2012 ◽

Vol 17 (03) ◽

pp. 375-377

Author(s):

Tomoo Inukai ◽

Kenzo Uchida ◽

Hisatoshi Baba

Keyword(s):

Magnetic Resonance ◽

Surgical Planning ◽

Three Dimensional ◽

Interesting Case ◽

3D Ct ◽

Mr Images ◽

Anterior Interosseous Artery ◽

Anterior Interosseous Nerve ◽

3D Ct Angiography ◽

Interosseous Artery

We report an interesting case of a neurinoma originating from the anterior interosseous nerve. Magnetic resonance (MR) images showed an egg-shaped, well-circumscribed mass on the volar side of the forearm. On the enhanced three-dimensional computer tomography (3D-CT), it was clearly demonstrated that the tumour had arterial feeding from the anterior interosseous artery. The enhanced 3D-CT angiography was useful in the pre-operative diagnosis and surgical planning of peripheral neurinomas.

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Conventional and Arthrographic Magnetic Resonance Techniques for Hip Evaluation: What the Radiologist Should Know

Seminars in Musculoskeletal Radiology ◽

10.1055/s-0039-1678729 ◽

2019 ◽

Vol 23 (03) ◽

pp. 227-251 ◽

Cited By ~ 5

Author(s):

Florian Schmaranzer ◽

Luis Cerezal ◽

Eva Llopis

Keyword(s):

Magnetic Resonance ◽

Sports Injuries ◽

Imaging Techniques ◽

Three Dimensional ◽

Pain Syndrome ◽

Volumetric Analysis ◽

Computer Assisted ◽

Current Standard ◽

Increasing Demand ◽

Magnetic Resonance Imaging Mri

AbstractOver the last 2 decades, the definition of pathomechanical concepts that link osseous deformities to chondrolabral damage and expose young and active patients to the risk of early osteoarthritis has led to a tremendous increase in the number of joint-preserving surgeries performed. The rise in arthroscopic procedures has led to an increasing demand for comprehensive preoperative magnetic resonance imaging (MRI) assessment of the hip joint. This includes conventional MRI for the assessment of extra-articular and periarticular pathologies such as greater trochanteric pain, deep gluteal pain syndrome, and sports injuries. Magnetic resonance arthrography with or without traction is reserved for the accurate evaluation of deformities associated with impingement and hip instability and for detecting the resulting intra-articular lesions. This article summarizes the current standard imaging techniques that the radiologist should know. It also explores the potential of computer-assisted analysis of three-dimensional MRI for virtual impingement simulation and volumetric analysis of cartilage composition and geometry.

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Application of three-dimensional magnetic resonance image registration for monitoring hip joint diseases

Magnetic Resonance Imaging ◽

10.1016/j.mri.2005.02.002 ◽

2005 ◽

Vol 23 (5) ◽

pp. 665-670 ◽

Cited By ~ 10

Author(s):

Masaki Takao ◽

Nobuhiko Sugano ◽

Takashi Nishii ◽

Hisahi Tanaka ◽

Jun Masumoto ◽

...

Keyword(s):

Magnetic Resonance ◽

Image Registration ◽

Hip Joint ◽

Magnetic Resonance Image ◽

Three Dimensional ◽

Joint Diseases

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A three-dimensional graph searching technique for cardiac border detection in sequential images and its application to magnetic resonance image data

[1990] Proceedings Computers in Cardiology ◽

10.1109/cic.1990.144164 ◽

2002 ◽

Cited By ~ 8

Author(s):

D.R. Thedens ◽

D.J. Skorton ◽

S.R. Fleagle

Keyword(s):

Magnetic Resonance ◽

Magnetic Resonance Image ◽

Three Dimensional ◽

Image Data ◽

Graph Searching ◽

Border Detection ◽

Sequential Images ◽

Dimensional Graph ◽

Magnetic Resonance Image Data

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Effect of slice thickness on brain magnetic resonance image texture analysis

BioMedical Engineering OnLine ◽

10.1186/1475-925x-9-60 ◽

2010 ◽

Vol 9 (1) ◽

pp. 60 ◽

Cited By ~ 23

Author(s):

Sami J Savio ◽

Lara CV Harrison ◽

Tiina Luukkaala ◽

Tomi Heinonen ◽

Prasun Dastidar ◽

...

Keyword(s):

Magnetic Resonance ◽

Texture Analysis ◽

Magnetic Resonance Image ◽

Image Texture ◽

Slice Thickness ◽

Image Texture Analysis ◽

Brain Magnetic Resonance Image

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Volumetric analysis of regional left ventricular function with real-time three-dimensional echocardiography: validation by magnetic resonance and clinical utility testing

Heart ◽

10.1136/hrt.2006.096040 ◽

2007 ◽

Vol 93 (5) ◽

pp. 572-578 ◽

Cited By ~ 50

Author(s):

H. Jaochim Nesser ◽

L. Sugeng ◽

C. Corsi ◽

L. Weinert ◽

J. Niel ◽

...

Keyword(s):

Magnetic Resonance ◽

Left Ventricular Function ◽

Ventricular Function ◽

Clinical Utility ◽

Three Dimensional ◽

Volumetric Analysis ◽

Left Ventricular ◽

Regional Left Ventricular Function ◽

Dimensional Echocardiography ◽

Three Dimensional Echocardiography

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Velopharyngeal Anatomy in 22q11.2 Deletion Syndrome: A Three-Dimensional Cephalometric Analysis

The Cleft Palate-Craniofacial Journal ◽

10.1597/04-193.1 ◽

2006 ◽

Vol 43 (4) ◽

pp. 446-456 ◽

Cited By ~ 36

Author(s):

Rachel A. Ruotolo ◽

Nestor A. Veitia ◽

Aaron Corbin ◽

Joseph McDonough ◽

Cynthia B. Solot ◽

...

Keyword(s):

Magnetic Resonance ◽

Tertiary Care ◽

Three Dimensional ◽

22Q11.2 Deletion Syndrome ◽

Magnetic Resonance Images ◽

Deletion Syndrome ◽

Control Group ◽

Study Group ◽

Slice Thickness ◽

22Q11.2 Deletion

Objective 22q11.2 deletion syndrome is the most common genetic cause of velopharyngeal dysfunction (VPD). Magnetic resonance imaging (MRI) is a promising method for noninvasive, three-dimensional (3D) assessment of velopharyngeal (VP) anatomy. The purpose of this study was to assess VP structure in patients with 22q11.2 deletion syndrome by using 3D MRI analysis. Design This was a retrospective analysis of magnetic resonance images obtained in patients with VPD associated with a 22q11.2 deletion compared with a normal control group. Setting This study was conducted at The Children's Hospital of Philadelphia, a pediatric tertiary care center. Patients, Participants The study group consisted of 5 children between the ages of 2.9 and 7.9 years, with 22q11.2 deletion syndrome confirmed by fluorescence in situ hybridization analysis. All had VPD confirmed by nasendoscopy or videofluoroscopy. The control population consisted of 123 unaffected patients who underwent MRI for reasons other than VP assessment. Interventions Axial and sagittal T1- and T2-weighted magnetic resonance images with 3-mm slice thickness were obtained from the orbit to the larynx in all patients by using a 1.5T Siemens Visions system. Outcome Measures Linear, angular, and volumetric measurements of VP structures were obtained from the magnetic resonance images with VIDA image-processing software. Results The study group demonstrated greater anterior and posterior cranial base and atlanto-dental angles. They also demonstrated greater pharyngeal cavity volume and width and lesser tonsillar and adenoid volumes. Conclusion Patients with a 22q11.2 deletion demonstrate significant alterations in VP anatomy that may contribute to VPD.

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Localization of stimulating electrodes in patients with Parkinson disease by using a three-dimensional atlas—magnetic resonance imaging coregistration method

Journal of Neurosurgery ◽

10.3171/jns.2003.99.1.0089 ◽

2003 ◽

Vol 99 (1) ◽

pp. 89-99 ◽

Cited By ~ 137

Author(s):

Jérôme Yelnik ◽

Philippe Damier ◽

Sophie Demeret ◽

David Gervais ◽

Eric Bardinet ◽

...

Keyword(s):

Magnetic Resonance ◽

Mr Imaging ◽

Parkinson Disease ◽

Three Dimensional ◽

Zona Incerta ◽

Mr Images ◽

Content Type ◽

Anatomical Localization ◽

Stimulating Electrodes ◽

Fine Print

Object. The aim of this study was to correlate the clinical improvement in patients with Parkinson disease (PD) treated using deep brain stimulation (DBS) of the subthalamic nucleus (STN) with the precise anatomical localization of stimulating electrodes. Methods. Localization was determined by superimposing figures from an anatomical atlas with postoperative magnetic resonance (MR) images obtained in each patient. This approach was validated by an analysis of experimental and clinical MR images of the electrode, and the development of a three-dimensional (3D) atlas—MR imaging coregistration method. The PD motor score was assessed through two contacts for each of two electrodes implanted in 10 patients: the “therapeutic contact” and the “distant contact” (that is, the next but one to the therapeutic contact). Seventeen therapeutic contacts were located within or on the border of the STN, most of which were associated with significant improvement of the four PD symptoms tested. Therapeutic contacts located in other structures (zona incerta, lenticular fasciculus, or midbrain reticular formation) were also linked to a significant positive effect. Stimulation applied through distant contacts located in the STN improved symptoms of PD, whereas that delivered through distant contacts in the remaining structures had variable effects ranging from worsening of symptoms to their improvement. Conclusions. The authors have demonstrated that 3D atlas—MR imaging coregistration is a reliable method for the precise localization of DBS electrodes on postoperative MR images. In addition, they have confirmed that although the STN is the main target during DBS treatment for PD, stimulation of surrounding regions, particularly the zona incerta or the lenticular fasciculus, can also improve symptoms of PD.

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