Spinal cord compression due to extramedullary hematopoiesis in homozygous thalassemia

1975 ◽  
Vol 42 (2) ◽  
pp. 212-216 ◽  
Author(s):  
Wlllem Luyendijk ◽  
Lodewijk Went ◽  
Hans D.G. Schaad
Keyword(s):  
Spastic Paraparesis ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Surgical Removal ◽  
Pathological Findings ◽  
Hematopoietic Tissue ◽  
Content Type ◽  
Vertebral Canal ◽  
Direct Extension ◽  
Fine Print

✓ The authors report a case of homozygous thalassemia in which a mass of hematopoietic tissue in the vertebral canal caused spastic paraparesis. Surgical removal of the tissue plus radiotherapy were successful. The pathological findings indicated direct extension of hematopoietic tissue from the adjacent bone marrow into the epidural space of the vertebral canal.

Spinal cord compression in a new homozygous variant of beta-thalassemia

1982 ◽  
Vol 57 (6) ◽  
pp. 846-848 ◽  
Author(s):  
Willem F. Luitjes ◽  
Reinder Braakman ◽  
Johannes Abels
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Genetic Variant ◽  
Cord Compression ◽  
Beta Thalassemia ◽  
Surgical Removal ◽  
Hematopoietic Tissue ◽  
Content Type ◽  
Cord Lesion ◽  
Fine Print

✓ A patient is reported with a new genetic variant of beta-thalassemia, who suffered from a progressive partial transverse cord lesion caused by epidural hematopoietic tissue. He recovered after partial surgical removal of this tissue and subsequent radiotherapy.

Progressive paraparesis due to thoracic extramedullary hematopoiesis in myelofibrosis

1993 ◽  
Vol 79 (1) ◽  
pp. 125-127 ◽  
Author(s):  
Nina De Klippel ◽  
Marie F. Dehou ◽  
Claire Bourgain ◽  
Rik Schots ◽  
Jaques De Keyser ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Hematopoietic Tissue ◽  
Content Type ◽  
Radiotherapy Alone ◽  
Progressive Paraparesis ◽  
Fine Print

✓ A patient with myelofibrosis who developed a progressive paraparesis caused by spinal cord compression due to thoracic extramedullary hematopoietic tissue is reported. He recovered well after local radiotherapy alone.

Chondroma of the cervical spine

1987 ◽  
Vol 66 (1) ◽  
pp. 128-130 ◽  
Author(s):  
Gérald Lozes ◽  
Ahmad Fawaz ◽  
Harry Perper ◽  
Philippe Devos ◽  
Pascal Benoit ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cervical Spine ◽  
Spinal Cord Compression ◽  
Vertebral Column ◽  
Cord Compression ◽  
Neurological Recovery ◽  
Surgical Removal ◽  
Content Type ◽  
Fine Print

✓ The authors report a case of cervical chondroma presenting with a syndrome of spinal cord compression in a 76-year-old woman. Total surgical removal of the lesion was followed by partial neurological recovery. Chondromas of the vertebral column are rarely reported in the literature.

Osteochondroma with spinal cord compression

1980 ◽  
Vol 52 (6) ◽  
pp. 842-845 ◽  
Author(s):  
F. John Palmer ◽  
Peter W. Blum
Keyword(s):  
Spinal Cord ◽  
Clinical Result ◽  
Neurological Complications ◽  
Cord Compression ◽  
Surgical Removal ◽  
Neural Arch ◽  
Content Type ◽  
Bone Dysplasias ◽  
The Relationship ◽  
Fine Print

✓ Multiple osteochondromatosis is the most common of the bone dysplasias, but neurological complications are rare. Osteochondromas of the spine usually arise from the neural arch. Tomography and myelography are useful in determining the site of origin and the relationship to the spinal cord. The tumor is benign, and surgical removal produces an excellent clinical result. Three cases are described illustrating the clinical and radiological manifestations of these tumors.

Nonsurgical approach to paraparesis due to extramedullary hematopoiesis

1995 ◽  
Vol 82 (4) ◽  
pp. 657-660 ◽  
Author(s):  
Khosrov Parsa ◽  
Ahmad Oreizy
Keyword(s):  
Spinal Cord ◽  
Radiation Therapy ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
The Other ◽  
Blood Transfusions ◽  
Therapeutic Tool ◽  
Content Type ◽  
Fine Print

✓ Two cases of spinal cord compression due to extradural extramedullary hematopoiesis are reported and the non-surgical means used for their diagnosis and treatment are presented. One patient was treated with blood transfusions and radiation therapy, the other with blood transfusions alone. Both patients have made almost complete clinical recoveries from spinal cord compression. A mechanism is proposed to explain how blood transfusions can serve as an important diagnostic, as well as a therapeutic, tool in the management of this entity.

A viable residual spinal hydatid cyst cured with albendazole

2000 ◽  
Vol 93 (1) ◽  
pp. 142-144 ◽  
Author(s):  
M. Kemali Baykaner ◽  
Fikret Doğulu ◽  
Gülyüz Öztürk ◽  
Naci Edali ◽  
Turgut Tali
Keyword(s):  
Hydatid Disease ◽  
Single Case ◽  
Cord Compression ◽  
Acute Onset ◽  
Neurological Deficits ◽  
Surgical Removal ◽  
Lower Extremity Weakness ◽  
Content Type ◽  
One Year ◽  
Fine Print

✓ Spinal hydatid disease is a rare entity that frequently yields to severe, acute-onset neurological deficits. Although the gold standard treatment is total surgical removal of the cysts without inducing any spillage, it may not be possible to perform this in patients with multiple and fragile cysts. In such cases, the neural structures should be adequately decompressed and albendazole should be administered promptly. The authors describe the case of a 13-year-old girl who was admitted with a history of back pain and acute-onset lower-extremity weakness. Magnetic resonance imaging scans demonstrated severe spinal cord compression caused by multiple cysts involving T-4 and the mediastinum. The patient underwent surgery, and the cysts were removed, except for one cyst that was hardly exposed. Following histopathological confirmation of spinal hydatid disease, she was treated with albendazole for 1 year. One year postoperatively, the residual cyst had gradually shrunk and had almost disappeared. Although a single case is not sufficiently promising, we believe that administration of albendazole is efficient to prevent recurrences in cases in which it is not possible to obtain total removal of the cysts without inducing spillage.

Gamma knife radiosurgery in the management of cavernous sinus meningiomas

2000 ◽  
Vol 93 (supplement_3) ◽  
pp. 68-73 ◽  
Author(s):  
Pierre-Hugues Roche ◽  
Jean Régis ◽  
Henry Dufour ◽  
Henri-Dominique Fournier ◽  
Christine Delsanti ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Tumor Growth ◽  
Gamma Knife ◽  
Cavernous Sinus ◽  
Gamma Knife Radiosurgery ◽  
Surgical Removal ◽  
Content Type ◽  
Cavernous Sinus Meningioma ◽  
The Mean ◽  
Fine Print

Object. The authors sought to assess the functional tolerance and tumor control rate of cavernous sinus meningiomas treated by gamma knife radiosurgery (GKS). Methods. Between July 1992 and October 1998, 92 patients harboring benign cavernous sinus meningiomas underwent GKS. The present study is concerned with the first 80 consecutive patients (63 women and 17 men). Gamma knife radiosurgery was performed as an alternative to surgical removal in 50 cases and as an adjuvant to microsurgery in 30 cases. The mean patient age was 49 years (range 6–71 years). The mean tumor volume was 5.8 cm3 (range 0.9–18.6 cm3). On magnetic resonance (MR) imaging the tumor was confined in 66 cases and extensive in 14 cases. The mean prescription dose was 28 Gy (range 12–50 Gy), delivered with an average of eight isocenters (range two–18). The median peripheral isodose was 50% (range 30–70%). Patients were evaluated at 6 months, and at 1, 2, 3, 5, and 7 years after GKS. The median follow-up period was 30.5 months (range 12–79 months). Tumor stabilization after GKS was noted in 51 patients, tumor shrinkage in 25 patients, and enlargement in four patients requiring surgical removal in two cases. The 5-year actuarial progression-free survival was 92.8%. No new oculomotor deficit was observed. Among the 54 patients with oculomotor nerve deficits, 15 improved, eight recovered, and one worsened. Among the 13 patients with trigeminal neuralgia, one worsened (contemporary of tumor growing), five remained unchanged, four improved, and three recovered. In a patient with a remnant surrounding the optic nerve and preoperative low vision (3/10) the decision was to treat the lesion and deliberately sacrifice the residual visual acuity. Only one transient unexpected optic neuropathy has been observed. One case of delayed intracavernous carotid artery occlusion occurred 3 months after GKS, without permanent deficit. Another patient presented with partial complex seizures 18 months after GKS. All cases of tumor growth and neurological deficits observed after GKS occurred before the use of GammaPlan. Since the initiation of systematic use of stereotactic MR imaging and computer-assisted modern dose planning, no more side effects or cases of tumor growth have occurred. Conclusions. Gamma knife radiosurgery was found to be an effective low morbidity—related tool for the treatment of cavernous sinus meningioma. In a significant number of patients, oculomotor functional restoration was observed. The treatment appears to be an alternative to surgical removal of confined enclosed cavernous sinus meningioma and should be proposed as an adjuvant to surgery in case of extensive meningiomas.

Preoperative and postoperative cognitive functioning in patients with frontal meningiomas

2003 ◽  
Vol 98 (1) ◽  
pp. 21-31 ◽  
Author(s):  
Oliver Tucha ◽  
Christian Smely ◽  
Michael Preier ◽  
Georg Becker ◽  
Geraldine M. Paul ◽  
...  
Keyword(s):  
Executive Functions ◽  
Cognitive Functioning ◽  
Time Course ◽  
Lesion Size ◽  
Test Battery ◽  
Surgical Removal ◽  
Specific Information ◽  
Content Type ◽  
Before And After ◽  
Fine Print

Object. There is presently no specific information available concerning the nature and course of cognitive deficits caused by intracranial meningiomas. In this prospective study the authors examined the cognitive functioning of patients with frontal meningiomas. Methods. Fifty-four patients with frontal meningiomas were examined neuropsychologically before and after neurosurgery. The test battery consisted of standardized instruments including those assessing memory, attention, visuoconstructive abilities, and executive functions. The time period between pre-and postoperative assessment ranged from 4 to 9 months. The patients' performance was compared with the results in 54 healthy adults who were also assessed twice by using the same test battery in a period ranging from 4 to 9 months. In addition, the effect on cognition of meningioma lateralization, localization, lesion size, edema, brain compression, time course, and the occurrence of preoperative seizures was analyzed. Conclusions. Except in the case of working memory, comparisons of pre- and postoperative assessments of cognition revealed no differences in memory, visuoconstructive abilities, or executive functions, although a postoperative improvement in attentional functions was observed. The results of this study indicate that the surgical removal of frontal meningiomas does not impair patients' cognitive functioning. Furthermore, improvements in attentional functions may occur in these patients.

Hemangiopericytoma of the spinal canal

1978 ◽  
Vol 49 (6) ◽  
pp. 914-920 ◽  
Author(s):  
Darrell J. Harris ◽  
Victor L. Fornasier ◽  
Kenneth E. Livingston
Keyword(s):  
Endothelial Cells ◽  
Differential Diagnosis ◽  
High Risk ◽  
Spinal Canal ◽  
Vertebral Column ◽  
Soft Tissues ◽  
Surgical Removal ◽  
Vascular Neoplasm ◽  
Content Type ◽  
Fine Print

✓ Hemangiopericytoma is a vascular neoplasm consisting of capillaries outlined by an intact basement membrane that separates the endothelial cells of the capillaries from the spindle-shaped tumor cells in the extravascular area. These neoplasms are found in soft tissues but have rarely been shown to involve the spinal canal. This is a report of three such cases. Surgical removal of the tumor from the spinal canal was technically difficult. A high risk of recurrence has been reported but in these three cases adjunctive radiotherapy appeared to be of benefit in controlling the progression of the disease. These cases, added to the six cases in the literature, confirm the existence of hemangiopericytoma involving the vertebral column with extension into the spinal canal. This entity should be included in the differential diagnosis of lesions of the spinal canal. The risk of intraoperative hemorrhage should be anticipated.

Surgical removal of bilateral papillomas of the choroid plexus of the lateral ventricles with resolution of hydrocephalus

1979 ◽  
Vol 50 (5) ◽  
pp. 677-681 ◽  
Author(s):  
Steven K. Gudeman ◽  
Humbert G. Sullivan ◽  
Michael J. Rosner ◽  
Donald P. Becker
Keyword(s):  
Cerebrospinal Fluid ◽  
Choroid Plexus ◽  
Large Volume ◽  
Surgical Removal ◽  
Tumor Removal ◽  
Content Type ◽  
Lateral Ventricles ◽  
Csf Diversion ◽  
Csf Production ◽  
Fine Print

✓ The authors report a patient with bilateral papillomas of the choroid plexus of the lateral ventricles with documentation of cerebrospinal fluid (CSF) hypersecretion causing hydrocephalus. Special attention is given to the large volume of CSF produced by these tumors (removal of one tumor reduced CSF outflow by one-half) and to the fact that CSF diversion was not required after both tumors were removed. Since tumor removal alone was sufficient to stop the progression of hydrocephalus, we feel that this case supports the concept that elevated CSF production by itself is sufficient to cause hydrocephalus in patients with papillomas of the choroid plexus.

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